| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.226202 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.180896 |
| NRXN3 | neurexin 3 | 0.0804514 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0561907 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0548875 |
| CDH13 | cadherin 13 | 0.0531507 |
| COL5A1 | collagen, type V, alpha 1 | 0.0519103 |
| GLIS3 | GLIS family zinc finger 3 | 0.0499005 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0483179 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0460528 |
| EFNA5 | ephrin-A5 | 0.0426372 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.041051 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0402827 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0398794 |
| DST | dystonin | 0.0394681 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0368552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0357989 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0354072 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0346801 |
| LOXL2 | lysyl oxidase-like 2 | 0.0346163 |
| RAD51B | RAD51 paralog B | 0.0335882 |
| LOX | lysyl oxidase | 0.0329216 |
| EGFR | epidermal growth factor receptor | 0.0320576 |
| VEGFC | vascular endothelial growth factor C | 0.0320531 |
| MAP1B | microtubule-associated protein 1B | 0.0304778 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0290557 |
| COL1A1 | collagen, type I, alpha 1 | 0.0289512 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0275453 |
| FN1 | fibronectin 1 | 0.0273899 |
| RAI14 | retinoic acid induced 14 | 0.0270958 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0269269 |
| OXR1 | oxidation resistance 1 | 0.0269016 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0268199 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0266952 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0266645 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0266394 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0260725 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0249273 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248445 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0244957 |
| ASPH | aspartate beta-hydroxylase | 0.0244828 |
| RASAL2 | RAS protein activator like 2 | 0.0243932 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0243375 |
| NAV1 | neuron navigator 1 | 0.0242439 |
| PRSS23 | protease, serine, 23 | 0.0239701 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0238581 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0232352 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0230382 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0227918 |
| NBAS | neuroblastoma amplified sequence | 0.0225676 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0224177 |
| CALU | calumenin | 0.0223396 |
| SMYD3 | SET and MYND domain containing 3 | 0.0221713 |
| PRELID2 | PRELI domain containing 2 | 0.022148 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0220887 |
| AOPEP | aminopeptidase O (putative) | 0.021556 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0214481 |
| FRMD4A | FERM domain containing 4A | 0.0212397 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0211048 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0207072 |
| MORF4L2 | mortality factor 4 like 2 | 0.0205957 |
| VEGFA | vascular endothelial growth factor A | 0.0203968 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0203241 |
| COL3A1 | collagen, type III, alpha 1 | 0.0202064 |
| VCL | vinculin | 0.0201774 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0201434 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0200582 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0197405 |
| SBF2 | SET binding factor 2 | 0.0197082 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0194861 |
| GSE1 | Gse1 coiled-coil protein | 0.0192722 |
| PDE10A | phosphodiesterase 10A | 0.0192486 |
| ZNF638 | zinc finger protein 638 | 0.0191828 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0191299 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0190288 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0189414 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0189101 |
| HMGA2 | high mobility group AT-hook 2 | 0.0188776 |
| PTK2 | protein tyrosine kinase 2 | 0.0188678 |
| COG5 | component of oligomeric golgi complex 5 | 0.018865 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0188185 |
| MED13L | mediator complex subunit 13-like | 0.0188065 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0186699 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0186403 |
| HDAC9 | histone deacetylase 9 | 0.0185774 |
| PRKCA | protein kinase C, alpha | 0.0185251 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0183656 |
| PDGFC | platelet derived growth factor C | 0.0182474 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.018172 |
| PARD3 | par-3 family cell polarity regulator | 0.0181238 |
| ZNF133 | zinc finger protein 133 | 0.018109 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0179402 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0179198 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0178893 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0178561 |
| JPH2 | junctophilin 2 | 0.0176736 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0176657 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0176467 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0175991 |
| FMNL2 | formin-like 2 | 0.0174779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.249086 |
| MT2A | metallothionein 2A | -0.194462 |
| TMSB10 | thymosin beta 10 | -0.17198 |
| VIM | vimentin | -0.107003 |
| UBC | ubiquitin C | -0.0892971 |
| B2M | beta-2-microglobulin | -0.0707092 |
| SDC4 | syndecan 4 | -0.0639194 |
| FTL | ferritin, light polypeptide | -0.0586135 |
| GRB10 | growth factor receptor-bound protein 10 | -0.050391 |
| CCNI | cyclin I | -0.0487951 |
| PTMA | prothymosin, alpha | -0.0485186 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0446675 |
| ANXA5 | annexin A5 | -0.0444003 |
| SPAG9 | sperm associated antigen 9 | -0.0442774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0418 |
| FNDC3B | fibronectin type III domain containing 3B | -0.040979 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0406517 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0397684 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0383422 |
| TXNIP | thioredoxin interacting protein | -0.0367477 |
| RPL37A | ribosomal protein L37a | -0.0362757 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0360323 |
| RPLP1 | ribosomal protein, large, P1 | -0.0357354 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0356623 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0344782 |
| WTAP | Wilms tumor 1 associated protein | -0.0333275 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0332718 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320712 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0318463 |
| ENO1 | enolase 1, (alpha) | -0.0311126 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0307269 |
| JUN | jun proto-oncogene | -0.0300019 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0299002 |
| S100A10 | S100 calcium binding protein A10 | -0.0296694 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0295236 |
| RPL23 | ribosomal protein L23 | -0.0289233 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0284933 |
| SRPK2 | SRSF protein kinase 2 | -0.0284536 |
| RPL32 | ribosomal protein L32 | -0.0283374 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0283206 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0278548 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0274544 |
| ZNF207 | zinc finger protein 207 | -0.0268212 |
| FLNB | filamin B, beta | -0.0267606 |
| OGA | O-GlcNAcase | -0.0262389 |
| RPL15 | ribosomal protein L15 | -0.0255283 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0252848 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0247159 |
| FLNA | filamin A, alpha | -0.0242226 |
| RPS8 | ribosomal protein S8 | -0.0241741 |
| RTN4 | reticulon 4 | -0.0241648 |
| IL6 | interleukin 6 | -0.023927 |
| RPS25 | ribosomal protein S25 | -0.0236914 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0235267 |
| TOP1 | topoisomerase (DNA) I | -0.0234616 |
| SEC24D | SEC24 family member D | -0.0234229 |
| SEC61G | Sec61 gamma subunit | -0.0234198 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.02316 |
| TPM2 | tropomyosin 2 (beta) | -0.023088 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0228678 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0227761 |
| RPL37 | ribosomal protein L37 | -0.0227226 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0226145 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0225637 |
| RPS6 | ribosomal protein S6 | -0.0224478 |
| RPL28 | ribosomal protein L28 | -0.0223658 |
| MTPN | myotrophin | -0.022289 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0222324 |
| RPS27A | ribosomal protein S27a | -0.0221589 |
| RPS11 | ribosomal protein S11 | -0.0221379 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.022074 |
| MATR3 | matrin 3 | -0.0220437 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0219918 |
| ACVR1 | activin A receptor, type I | -0.0218513 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0216882 |
| H3-3B | H3.3 histone B | -0.021671 |
| HMGB2 | high mobility group box 2 | -0.0216291 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0213729 |
| SEPTIN7 | septin 7 | -0.0212968 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0212233 |
| LMNA | lamin A/C | -0.0211216 |
| GANAB | glucosidase, alpha; neutral AB | -0.0210574 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0208352 |
| AFDN | afadin, adherens junction formation factor | -0.0207559 |
| ABI1 | abl-interactor 1 | -0.0206695 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0206628 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0205846 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0205838 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.020493 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0203707 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0203144 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.020289 |
| FNBP4 | formin binding protein 4 | -0.0201314 |
| ANXA1 | annexin A1 | -0.0201045 |
| FAM3C | family with sequence similarity 3, member C | -0.020077 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0200063 |
| TFG | TRK-fused gene | -0.0199621 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0197932 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0197825 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0197585 |
