| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.250561 |
| LDHA | lactate dehydrogenase A | 0.084723 |
| ZNF292 | zinc finger protein 292 | 0.0769332 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0719239 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0676909 |
| NUP58 | nucleoporin 58 | 0.0667265 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0648347 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0633768 |
| SMYD3 | SET and MYND domain containing 3 | 0.0620821 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0603808 |
| PKM | pyruvate kinase, muscle | 0.0581334 |
| RBM39 | RNA binding motif protein 39 | 0.0512833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0508764 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0501885 |
| CENPF | centromere protein F, 350/400kDa | 0.0477871 |
| ENO1 | enolase 1, (alpha) | 0.0451713 |
| SETD5 | SET domain containing 5 | 0.044287 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.043978 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0438783 |
| YAP1 | Yes-associated protein 1 | 0.0436019 |
| CEP250 | centrosomal protein 250kDa | 0.0433454 |
| TPX2 | TPX2, microtubule-associated | 0.0422025 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0419564 |
| GOLGA4 | golgin A4 | 0.0418117 |
| OXSR1 | oxidative stress responsive 1 | 0.0404676 |
| HELZ | helicase with zinc finger | 0.0403109 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0395558 |
| SPAG9 | sperm associated antigen 9 | 0.0392969 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0386774 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0386416 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0383624 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0371313 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0370919 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0370887 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0370354 |
| TMEM123 | transmembrane protein 123 | 0.0369849 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.036812 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0367609 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0366802 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0357514 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0356795 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0350502 |
| DIAPH3 | diaphanous-related formin 3 | 0.0349969 |
| TXNRD1 | thioredoxin reductase 1 | 0.0348785 |
| ECT2 | epithelial cell transforming 2 | 0.0340014 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0334861 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0333414 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0330737 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0325488 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0324534 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0322878 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0322545 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321441 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0321115 |
| CLTC | clathrin, heavy chain (Hc) | 0.0319928 |
| TBK1 | TANK-binding kinase 1 | 0.0318418 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0314016 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0313013 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0312413 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0309592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0309253 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0306408 |
| CANX | calnexin | 0.0305878 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0304945 |
| NBAS | neuroblastoma amplified sequence | 0.0304475 |
| PHF21A | PHD finger protein 21A | 0.0302642 |
| PCBP2 | poly(rC) binding protein 2 | 0.0300845 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0299085 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0298654 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0296348 |
| SEPTIN2 | septin 2 | 0.0294967 |
| KIF5B | kinesin family member 5B | 0.0293752 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0289916 |
| COG5 | component of oligomeric golgi complex 5 | 0.0289758 |
| ANLN | anillin, actin binding protein | 0.0287322 |
| CUL5 | cullin 5 | 0.0283479 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0283088 |
| MSN | moesin | 0.0282924 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0276535 |
| PHF20 | PHD finger protein 20 | 0.0274597 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0272782 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.027228 |
| TNRC6B | trinucleotide repeat containing 6B | 0.027116 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0268558 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.026846 |
| COG6 | component of oligomeric golgi complex 6 | 0.0265032 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0264981 |
| KLHL24 | kelch-like family member 24 | 0.0263742 |
| CUL3 | cullin 3 | 0.026308 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.026277 |
| JMJD1C | jumonji domain containing 1C | 0.0262642 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0262367 |
| ANXA5 | annexin A5 | 0.0261292 |
| RPLP0 | ribosomal protein, large, P0 | 0.0261092 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0261012 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0259142 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0258444 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0258251 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.025818 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0257368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | -0.084863 |
| TMSB10 | thymosin beta 10 | -0.0745579 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0689893 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0651812 |
| ANGPTL4 | angiopoietin-like 4 | -0.0609381 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0555911 |
| PRR16 | proline rich 16 | -0.0472906 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0457051 |
| RIGI | RNA sensor RIG-I | -0.0447176 |
| VIM | vimentin | -0.0383362 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0379482 |
| DST | dystonin | -0.0373314 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0369073 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367349 |
| RAI14 | retinoic acid induced 14 | -0.0351499 |
| PCED1B | PC-esterase domain containing 1B | -0.0342957 |
| MT2A | metallothionein 2A | -0.0342815 |
| GPC5 | glypican 5 | -0.032897 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0325682 |
| CD44 | CD44 molecule (Indian blood group) | -0.0325365 |
| PODXL | podocalyxin-like | -0.0324662 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0324301 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0317764 |
| COL5A1 | collagen, type V, alpha 1 | -0.0316306 |
| PRSS23 | protease, serine, 23 | -0.0315489 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0313676 |
| SDC4 | syndecan 4 | -0.0313321 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0299592 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0292582 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.029057 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0285791 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0272937 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0261989 |
| RPL19 | ribosomal protein L19 | -0.0261176 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0254643 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.025443 |
| MYO9B | myosin IXB | -0.025273 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0248451 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244229 |
| SVIL | supervillin | -0.023995 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0234689 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0233392 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0232972 |
| STXBP1 | syntaxin binding protein 1 | -0.0227933 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0222691 |
| NALCN | sodium leak channel, non selective | -0.0220977 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0220304 |
| S100A10 | S100 calcium binding protein A10 | -0.0220127 |
| CAVIN1 | caveolae associated protein 1 | -0.0218831 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0217023 |
| FMN1 | formin 1 | -0.0216712 |
| HLA-B | major histocompatibility complex, class I, B | -0.0215516 |
| IGF2 | insulin-like growth factor 2 | -0.0215078 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.021494 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0213271 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0212226 |
| ZFHX3 | zinc finger homeobox 3 | -0.0211605 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0208783 |
| PLEK2 | pleckstrin 2 | -0.0207819 |
| RIN2 | Ras and Rab interactor 2 | -0.0207759 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0205809 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0203518 |
| HLA-C | major histocompatibility complex, class I, C | -0.020281 |
| NPAS2 | neuronal PAS domain protein 2 | -0.020257 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0200366 |
| CCND1 | cyclin D1 | -0.0198116 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0196487 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0190841 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0189463 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0188958 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0187515 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0185346 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | -0.0182269 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0180415 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0180162 |
| NAV3 | neuron navigator 3 | -0.0179217 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0177886 |
| THBS1 | thrombospondin 1 | -0.0177516 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0176139 |
| RPS14 | ribosomal protein S14 | -0.0173984 |
| JUN | jun proto-oncogene | -0.0173934 |
| RPL9 | ribosomal protein L9 | -0.0172103 |
| NRG1 | neuregulin 1 | -0.0171535 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0169677 |
| MYO10 | myosin X | -0.0169545 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | -0.016682 |
| TBCA | tubulin folding cofactor A | -0.0165185 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0164869 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0164207 |
| EGR1 | early growth response 1 | -0.0163383 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.01632 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0162689 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.016148 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0159741 |
| RPS27A | ribosomal protein S27a | -0.01597 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0159425 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0157094 |
| ANXA2 | annexin A2 | -0.0156243 |
| NLK | nemo-like kinase | -0.015537 |
| JAK1 | Janus kinase 1 | -0.0154991 |
