| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sivelestat (sodium tetrahydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sivelestat (sodium tetrahydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.33975 |
| NRG1 | neuregulin 1 | 0.167655 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.164393 |
| CANX | calnexin | 0.148482 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.131588 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.125992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123488 |
| SQSTM1 | sequestosome 1 | 0.11164 |
| ASPH | aspartate beta-hydroxylase | 0.108832 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0932093 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0891283 |
| GLIS3 | GLIS family zinc finger 3 | 0.0827041 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0719432 |
| STC2 | stanniocalcin 2 | 0.0711741 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0701286 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0690506 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.063872 |
| ITGA1 | integrin, alpha 1 | 0.0625206 |
| SYT1 | synaptotagmin I | 0.0611152 |
| AHR | aryl hydrocarbon receptor | 0.0601473 |
| CD109 | CD109 molecule | 0.0588156 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0575099 |
| NRP1 | neuropilin 1 | 0.0563177 |
| SFTPA2 | surfactant protein A2 | 0.0560641 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0557971 |
| ENO1 | enolase 1, (alpha) | 0.0551503 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0546167 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0541182 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0526748 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0519939 |
| RUNX2 | runt-related transcription factor 2 | 0.051901 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0507656 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0501497 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0485703 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0467269 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0459458 |
| VCL | vinculin | 0.0448274 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0438407 |
| LOC112694756 | uncharaterized LOC112694756 | 0.043525 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0435014 |
| PGK1 | phosphoglycerate kinase 1 | 0.0429594 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.042535 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0422365 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0415451 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0412531 |
| EFNA5 | ephrin-A5 | 0.0410457 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0405799 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0404602 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0400218 |
| TXNIP | thioredoxin interacting protein | 0.0398803 |
| PKM | pyruvate kinase, muscle | 0.0394589 |
| GLUL | glutamate-ammonia ligase | 0.0390481 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0389018 |
| HDLBP | high density lipoprotein binding protein | 0.0387546 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0381003 |
| CALR | calreticulin | 0.0379465 |
| RNF213 | ring finger protein 213 | 0.0376824 |
| ACTN4 | actinin, alpha 4 | 0.0374218 |
| HLA-B | major histocompatibility complex, class I, B | 0.0372132 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0371484 |
| TXNRD1 | thioredoxin reductase 1 | 0.037101 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0370635 |
| RTN4 | reticulon 4 | 0.0363196 |
| PRELID2 | PRELI domain containing 2 | 0.0362508 |
| PLIN2 | perilipin 2 | 0.0362392 |
| RAI14 | retinoic acid induced 14 | 0.0361626 |
| DST | dystonin | 0.0357057 |
| HMGA2 | high mobility group AT-hook 2 | 0.0356319 |
| ETV6 | ets variant 6 | 0.0351163 |
| COPA | coatomer protein complex, subunit alpha | 0.0347608 |
| CALU | calumenin | 0.0347514 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0339049 |
| RBM39 | RNA binding motif protein 39 | 0.0334163 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0329516 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0322538 |
| LDHA | lactate dehydrogenase A | 0.0321107 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0319935 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0317329 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0317189 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0316737 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0313797 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0313127 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.031263 |
| FBXO11 | F-box protein 11 | 0.0311698 |
| AEBP2 | AE binding protein 2 | 0.0310847 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0310431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030841 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0303817 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0296347 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0295907 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0293938 |
| PTK2 | protein tyrosine kinase 2 | 0.0293794 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0292955 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0292478 |
| HPCAL1 | hippocalcin-like 1 | 0.0292185 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291788 |
| EZR | ezrin | 0.0290829 |
| AHNAK | AHNAK nucleoprotein | 0.0288897 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0288761 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.028875 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.111171 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0559855 |
| RPS12 | ribosomal protein S12 | -0.0536217 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.046114 |
| RPL37A | ribosomal protein L37a | -0.0411021 |
| RPS6 | ribosomal protein S6 | -0.0378146 |
| VIM | vimentin | -0.0376695 |
| RPL9 | ribosomal protein L9 | -0.037389 |
| RPL26 | ribosomal protein L26 | -0.0364781 |
| CENPF | centromere protein F, 350/400kDa | -0.0350347 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0316929 |
| B2M | beta-2-microglobulin | -0.0310617 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0282926 |
| TMEM165 | transmembrane protein 165 | -0.0282785 |
| RPS19 | ribosomal protein S19 | -0.0266407 |
| RPL12 | ribosomal protein L12 | -0.025883 |
| RPS2 | ribosomal protein S2 | -0.0257719 |
| RPS8 | ribosomal protein S8 | -0.0255085 |
| RPS3 | ribosomal protein S3 | -0.0249407 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0248643 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0243409 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0222301 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022159 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0216988 |
| S100A6 | S100 calcium binding protein A6 | -0.0204607 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0203546 |
| RPL37 | ribosomal protein L37 | -0.0202926 |
| RPLP1 | ribosomal protein, large, P1 | -0.0198756 |
| RPS16 | ribosomal protein S16 | -0.01981 |
| RPLP2 | ribosomal protein, large, P2 | -0.0196597 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0187397 |
| RPS27A | ribosomal protein S27a | -0.018625 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0185046 |
| RPL11 | ribosomal protein L11 | -0.0178363 |
| CBX3 | chromobox homolog 3 | -0.0174386 |
| RNF145 | ring finger protein 145 | -0.0157909 |
| RPS27 | ribosomal protein S27 | -0.0153311 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0152308 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0151983 |
| RPL36 | ribosomal protein L36 | -0.0151606 |
| RPS29 | ribosomal protein S29 | -0.0149974 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0148814 |
| RPL19 | ribosomal protein L19 | -0.0148176 |
| RPS17 | ribosomal protein S17 | -0.0143623 |
| LDHB | lactate dehydrogenase B | -0.0137081 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0137043 |
| RPL18 | ribosomal protein L18 | -0.013591 |
| HDGF | hepatoma-derived growth factor | -0.013559 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0135156 |
| SERF2 | small EDRK-rich factor 2 | -0.0133831 |
| RPL7A | ribosomal protein L7a | -0.0131703 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0131471 |
| RPL7 | ribosomal protein L7 | -0.0129008 |
| RPL5 | ribosomal protein L5 | -0.012855 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0125182 |
| RPL21 | ribosomal protein L21 | -0.0124937 |
| RPL30 | ribosomal protein L30 | -0.0124342 |
| PPHLN1 | periphilin 1 | -0.012353 |
| RBM25 | RNA binding motif protein 25 | -0.0122118 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0121409 |
| CD44 | CD44 molecule (Indian blood group) | -0.0121179 |
| FOSL1 | FOS-like antigen 1 | -0.012103 |
| PDCD5 | programmed cell death 5 | -0.0120643 |
| SET | SET nuclear proto-oncogene | -0.0119474 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.0119283 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0119244 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0118462 |
| RPS25 | ribosomal protein S25 | -0.011839 |
| RPS20 | ribosomal protein S20 | -0.0117888 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0117054 |
| PNN | pinin, desmosome associated protein | -0.0116856 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.01154 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0114925 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0114132 |
| NUP58 | nucleoporin 58 | -0.0114019 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0113536 |
| RO60 | Ro60, Y RNA binding protein | -0.0113237 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0112558 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.011241 |
| RPL8 | ribosomal protein L8 | -0.0111103 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0109469 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.010899 |
| RPL27 | ribosomal protein L27 | -0.0107928 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0107408 |
| RPS21 | ribosomal protein S21 | -0.0105181 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0102706 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0102019 |
| CSNK1E | casein kinase 1, epsilon | -0.00997037 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00996025 |
| RPS23 | ribosomal protein S23 | -0.00991299 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.00985727 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.00981377 |
| RPL38 | ribosomal protein L38 | -0.00978969 |
| S100A9 | S100 calcium binding protein A9 | -0.00948028 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00944973 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.00926385 |
| TMF1 | TATA element modulatory factor 1 | -0.00925815 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.00925699 |
| ATP5MK | ATP synthase membrane subunit k | -0.00923876 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.00923602 |
