Skin Carcinogenesis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1519346
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Genes

191 genes associated with the disease Skin Carcinogenesis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADA adenosine deaminase
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BCL2 B-cell CLL/lymphoma 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CIRBP cold inducible RNA binding protein
CKAP4 cytoskeleton-associated protein 4
CLU clusterin
CRABP2 cellular retinoic acid binding protein 2
CRISP2 cysteine-rich secretory protein 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DHODH dihydroorotate dehydrogenase (quinone)
DLX3 distal-less homeobox 3
EGFR epidermal growth factor receptor
EI24 etoposide induced 2.4
ELANE elastase, neutrophil expressed
ENG endoglin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FANCD2 Fanconi anemia, complementation group D2
FAT1 FAT atypical cadherin 1
FGFBP1 fibroblast growth factor binding protein 1
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXE1 forkhead box E1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GC group-specific component (vitamin D binding protein)
GDF15 growth differentiation factor 15
GPR55 G protein-coupled receptor 55
GPX1 glutathione peroxidase 1
GSTK1 glutathione S-transferase kappa 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IGF1 insulin-like growth factor 1 (somatomedin C)
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL32 interleukin 32
INSR insulin receptor
IRF6 interferon regulatory factor 6
IRF9 interferon regulatory factor 9
ITGAV integrin, alpha V
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KRT1 keratin 1, type II
LEP leptin
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOR loricrin
LOXL2 lysyl oxidase-like 2
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LTA4H leukotriene A4 hydrolase
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK7 mitogen-activated protein kinase 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MMP26 matrix metallopeptidase 26
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NSD1 nuclear receptor binding SET domain protein 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
ODC1 ornithine decarboxylase 1
OGG1 8-oxoguanine DNA glycosylase
PARD3 par-3 family cell polarity regulator
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PBK PDZ binding kinase
PDPN podoplanin
PEA15 phosphoprotein enriched in astrocytes 15
PGF placental growth factor
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PML promyelocytic leukemia
POLH polymerase (DNA directed), eta
PPARG peroxisome proliferator-activated receptor gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRSS55 protease, serine, 55
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB11A RAB11A, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD18 RAD18 E3 ubiquitin protein ligase
RALBP1 ralA binding protein 1
RALGDS ral guanine nucleotide dissociation stimulator
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP2 retinol binding protein 2, cellular
RIT2 Ras-like without CAAX 2
RMC1 regulator of MON1-CCZ1
RNF7 ring finger protein 7
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPE65 retinal pigment epithelium-specific protein 65kDa
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SNAI1 snail family zinc finger 1
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SPAG11A sperm associated antigen 11A
SPAG11B sperm associated antigen 11B
SPPL2B signal peptide peptidase like 2B
SPZ1 spermatogenic leucine zipper 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBPL1 TBP-like 1
TERF2 telomeric repeat binding factor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TNF tumor necrosis factor
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP53RK TP53 regulating kinase
TP63 tumor protein p63
TRAF1 TNF receptor-associated factor 1
TREX2 three prime repair exonuclease 2
TRIM16 tripartite motif containing 16
TRIM32 tripartite motif containing 32
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TXN thioredoxin
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UVRAG UV radiation resistance associated
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
XPC xeroderma pigmentosum, complementation group C
YAP1 Yes-associated protein 1
ZNF645 zinc finger protein 645