Skin Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A skin cancer that is located_in tissues of the skin and develops from epithelial cells. (Human Disease Ontology, DOID_3451)
External Link https://www.disgenet.org/browser/0/1/0/C0699893
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Genes

127 genes associated with the disease Skin Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CABIN1 calcineurin binding protein 1
CCND1 cyclin D1
CCR4 chemokine (C-C motif) receptor 4
CD24 CD24 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX2 caudal type homeobox 2
CLPTM1L CLPTM1-like
COX2
CRABP2 cellular retinoic acid binding protein 2
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DMKN dermokine
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EPHA1 EPH receptor A1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
FAS Fas cell surface death receptor
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FHIT fragile histidine triad
FOXO3 forkhead box O3
GLI2 GLI family zinc finger 2
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPX4 glutathione peroxidase 4
GRHL3 grainyhead-like 3 (Drosophila)
GSTA4 glutathione S-transferase alpha 4
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAL histidine ammonia-lyase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HMGA1 high mobility group AT-hook 1
HPGDS hematopoietic prostaglandin D synthase
HRAS Harvey rat sarcoma viral oncogene homolog
HRH2 histamine receptor H2
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IL10 interleukin 10
IL4R interleukin 4 receptor
INPP5K inositol polyphosphate-5-phosphatase K
IRF4 interferon regulatory factor 4
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLK6 kallikrein-related peptidase 6
KRT19 keratin 19, type I
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP11 matrix metallopeptidase 11
MRC1 mannose receptor, C type 1
MSC musculin
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NLRP1 NLR family, pyrin domain containing 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
PDCD1 programmed cell death 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAT plasminogen activator, tissue
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNA2 plexin A2
PTAFR platelet-activating factor receptor
PTCH1 patched 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RBP2 retinol binding protein 2, cellular
RCE1 Ras converting CAAX endopeptidase 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRBP1 ribosome binding protein 1
SASH1 SAM and SH3 domain containing 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHARPIN SHANK-associated RH domain interactor
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SNW1 SNW domain containing 1
SPHKAP SPHK1 interactor, AKAP domain containing
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF410 zinc finger protein 410