Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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386 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABHD16A abhydrolase domain containing 16A
ABI1 abl-interactor 1
ABT1 activator of basal transcription 1
ADAD2 adenosine deaminase domain containing 2
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADGRG5 adhesion G protein-coupled receptor G5
ADM adrenomedullin
ADRBK1 adrenergic, beta, receptor kinase 1
AIP aryl hydrocarbon receptor interacting protein
AKR7L aldo-keto reductase family 7-like (gene/pseudogene)
AMT aminomethyltransferase
ANGPTL3 angiopoietin-like 3
ANKRD13D ankyrin repeat domain 13 family, member D
ANKRD30B ankyrin repeat domain 30B
ANKRD30BL ankyrin repeat domain 30B-like
ANKRD30BP2 ankyrin repeat domain 30B pseudogene 2
ANKRD37 ankyrin repeat domain 37
ANO9 anoctamin 9
ANXA3 annexin A3
APOC2 apolipoprotein C-II
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMC3 armadillo repeat containing 3
ARMCX2 armadillo repeat containing, X-linked 2
ATAD3C ATPase family, AAA domain containing 3C
ATF6B activating transcription factor 6 beta
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
BEGAIN brain-enriched guanylate kinase-associated
BHLHE40 basic helix-loop-helix family, member e40
BPHL biphenyl hydrolase-like (serine hydrolase)
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTF3L4 basic transcription factor 3-like 4
BTN2A1 butyrophilin, subfamily 2, member A1
BTN2A2 butyrophilin, subfamily 2, member A2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C10ORF76 chromosome 10 open reading frame 76
C10ORF90 chromosome 10 open reading frame 90
C11ORF80 chromosome 11 open reading frame 80
C18ORF25 chromosome 18 open reading frame 25
C2 complement component 2
C3ORF38 chromosome 3 open reading frame 38
C5ORF34 chromosome 5 open reading frame 34
C8ORF46 chromosome 8 open reading frame 46
CA6 carbonic anhydrase VI
CABP4 calcium binding protein 4
CACUL1 CDK2-associated, cullin domain 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASQ2 calsequestrin 2 (cardiac muscle)
CATSPER2 cation channel, sperm associated 2
CATSPERG catsper channel auxiliary subunit gamma
CCDC154 coiled-coil domain containing 154
CCDC155 coiled-coil domain containing 155
CCDC183 coiled-coil domain containing 183
CCND1 cyclin D1
CCNDBP1 cyclin D-type binding-protein 1
CCNL1 cyclin L1
CCR10 chemokine (C-C motif) receptor 10
CD244 CD244 molecule, natural killer cell receptor 2B4
CEP192 centrosomal protein 192kDa
CEP57 centrosomal protein 57kDa
CHDH choline dehydrogenase
CHMP4C charged multivesicular body protein 4C
CKMT1A creatine kinase, mitochondrial 1A
CKMT1B creatine kinase, mitochondrial 1B
CLDN7 claudin 7
CLEC5A C-type lectin domain family 5, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTF ciliary neurotrophic factor
CNTNAP3 contactin associated protein-like 3
COL6A4P1 collagen, type VI, alpha 4 pseudogene 1
CORO1B coronin, actin binding protein, 1B
CPEB4 cytoplasmic polyadenylation element binding protein 4
CSDE1 cold shock domain containing E1, RNA-binding
CTAG1B cancer/testis antigen 1B
CTAG2 cancer/testis antigen 2
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1
DCC DCC netrin 1 receptor
DCDC2 doublecortin domain containing 2
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDIT4 DNA-damage-inducible transcript 4
DEK DEK proto-oncogene
DENND1A DENN/MADD domain containing 1A
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DMKN dermokine
DSCR9 Down syndrome critical region 9 (non-protein coding)
DTNBP1 dystrobrevin binding protein 1
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
EAF1 ELL associated factor 1
ECHDC2 enoyl CoA hydratase domain containing 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
ELMO3 engulfment and cell motility 3
ENOSF1 enolase superfamily member 1
EPHA8 EPH receptor A8
ERICH1 glutamate-rich 1
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ETV7 ets variant 7
EWSAT1 Ewing sarcoma associated transcript 1
FADD Fas (TNFRSF6)-associated via death domain
FAM157B family with sequence similarity 157, member B
FAM161A family with sequence similarity 161, member A
FAM196B family with sequence similarity 196, member B
FAM50B family with sequence similarity 50, member B
FAM86C1 family with sequence similarity 86, member C1
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FBLN7 fibulin 7
FBXO27 F-box protein 27
FGF22 fibroblast growth factor 22
FSD1L fibronectin type III and SPRY domain containing 1-like
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GBP4 guanylate binding protein 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDF15 growth differentiation factor 15
GFOD1 glucose-fructose oxidoreductase domain containing 1
GH2 growth hormone 2
GLCE glucuronic acid epimerase
GNL1 guanine nucleotide binding protein-like 1
GOLT1A golgi transport 1A
GPR152 G protein-coupled receptor 152
GPR158 G protein-coupled receptor 158
GPR27 G protein-coupled receptor 27
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAPLN3 hyaluronan and proteoglycan link protein 3
HCP5 HLA complex P5 (non-protein coding)
HIST1H3I histone cluster 1, H3i
HIST1H4B histone cluster 1, H4b
HIST2H2AB histone cluster 2, H2ab
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HMG20B high mobility group 20B
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HORMAD1 HORMA domain containing 1
HSF4 heat shock transcription factor 4
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5L immediate early response 5-like
IFITM4P interferon induced transmembrane protein 4 pseudogene
IL17RE interleukin 17 receptor E
IL18BP interleukin 18 binding protein
INPP5F inositol polyphosphate-5-phosphatase F
IQCH IQ motif containing H
IRX6 iroquois homeobox 6
ISL1 ISL LIM homeobox 1
ITLN2 intelectin 2
KAAG1 kidney associated antigen 1
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDM2A lysine (K)-specific demethylase 2A
KIAA1328 KIAA1328
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLK10 kallikrein-related peptidase 10
KREMEN2 kringle containing transmembrane protein 2
KRT8 keratin 8, type II
KRTAP20-4 keratin associated protein 20-4
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae)
LAMP3 lysosomal-associated membrane protein 3
LCN10 lipocalin 10
LEMD1 LEM domain containing 1
LGSN lengsin, lens protein with glutamine synthetase domain
LINGO4 leucine rich repeat and Ig domain containing 4
LOC100130872 uncharacterized LOC100130872
LOC100132287 uncharacterized LOC100132287
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRRC16A leucine rich repeat containing 16A
LRRC75A leucine rich repeat containing 75A
LRRK2 leucine-rich repeat kinase 2
LRRN2 leucine rich repeat neuronal 2
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
LYPD5 LY6/PLAUR domain containing 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAG myelin associated glycoprotein
MED30 mediator complex subunit 30
MEGF6 multiple EGF-like-domains 6
MEI1 meiosis inhibitor 1
METTL4 methyltransferase like 4
MEX3C mex-3 RNA binding family member C
MFAP1 microfibrillar-associated protein 1
MICB MHC class I polypeptide-related sequence B
MRPS30 mitochondrial ribosomal protein S30
MTMR9LP myotubularin related protein 9-like, pseudogene
MXI1 MAX interactor 1, dimerization protein
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCNOS MYCN opposite strand
MYH4 myosin, heavy chain 4, skeletal muscle
MYSM1 Myb-like, SWIRM and MPN domains 1
MYT1L myelin transcription factor 1-like
N4BP3 NEDD4 binding protein 3
NADSYN1 NAD synthetase 1
NALCN sodium leak channel, non selective
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NEURL3 neuralized E3 ubiquitin protein ligase 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOBOX NOBOX oogenesis homeobox
NOL7 nucleolar protein 7, 27kDa
NOXA1 NADPH oxidase activator 1
NPHP4 nephronophthisis 4
NQO2 NAD(P)H dehydrogenase, quinone 2
NRBP2 nuclear receptor binding protein 2
NSG1 neuron specific gene family member 1
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
OARD1 O-acyl-ADP-ribose deacylase 1
ODF3L2 outer dense fiber of sperm tails 3-like 2
OPTN optineurin
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2A5 olfactory receptor, family 2, subfamily A, member 5
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR56A3 olfactory receptor, family 56, subfamily A, member 3
OR56A4 olfactory receptor, family 56, subfamily A, member 4
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR5B12 olfactory receptor, family 5, subfamily B, member 12
OR5T3 olfactory receptor, family 5, subfamily T, member 3
OR7E5P olfactory receptor, family 7, subfamily E, member 5 pseudogene
OR8G5 olfactory receptor, family 8, subfamily G, member 5
ORAOV1 oral cancer overexpressed 1
PAGE2 P antigen family, member 2 (prostate associated)
PC pyruvate carboxylase
PCDHGA3 protocadherin gamma subfamily A, 3
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PGBD2 piggyBac transposable element derived 2
PGK2 phosphoglycerate kinase 2
PHACTR1 phosphatase and actin regulator 1
PHF1 PHD finger protein 1
PICK1 protein interacting with PRKCA 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1P1 phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PNMA5 paraneoplastic Ma antigen family member 5
POC1A POC1 centriolar protein A
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRG3 proteoglycan 3
PRPF4B pre-mRNA processing factor 4B
PRRT4 proline-rich transmembrane protein 4
PRSS21 protease, serine, 21 (testisin)
PRSS30P protease, serine, 30, pseudogene
PRSS41 protease, serine, 41
PRSS45 protease, serine, 45
PSEN1 presenilin 1
PSG3 pregnancy specific beta-1-glycoprotein 3
PSG4 pregnancy specific beta-1-glycoprotein 4
PSG5 pregnancy specific beta-1-glycoprotein 5
PSG6 pregnancy specific beta-1-glycoprotein 6
PSG8 pregnancy specific beta-1-glycoprotein 8
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PXDC1 PX domain containing 1
RADIL Ras association and DIL domains
RAG1 recombination activating gene 1
RAP2B RAP2B, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASAL1 RAS protein activator like 1 (GAP1 like)
RASD1 RAS, dexamethasone-induced 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBM18 RNA binding motif protein 18
RCE1 Ras converting CAAX endopeptidase 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RGS21 regulator of G-protein signaling 21
RGS7 regulator of G-protein signaling 7
RHOD ras homolog family member D
RHPN1 rhophilin, Rho GTPase binding protein 1
RHPN2 rhophilin, Rho GTPase binding protein 2
RIC3 RIC3 acetylcholine receptor chaperone
RING1 ring finger protein 1
RNF121 ring finger protein 121
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPAP3 RNA polymerase II associated protein 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSBN1 round spermatid basic protein 1
SCP2 sterol carrier protein 2
SEH1L SEH1-like (S. cerevisiae)
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERTAD4-AS1 SERTAD4 antisense RNA 1
SH3D21 SH3 domain containing 21
SIK1 salt-inducible kinase 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKINTL Skint-like, pseudogene
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A20 solute carrier family 22, member 20
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9
SLC6A10P solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLFN13 schlafen family member 13
SNORA15 small nucleolar RNA, H/ACA box 15
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA8 small nucleolar RNA, H/ACA box 8
SPERT spermatid associated
SPIRE1 spire-type actin nucleation factor 1
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SSH3 slingshot protein phosphatase 3
ST20 suppressor of tumorigenicity 20
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STAT5A signal transducer and activator of transcription 5A
STK19 serine/threonine kinase 19
STRC stereocilin
SUMO4 small ubiquitin-like modifier 4
SYNE4 spectrin repeat containing, nuclear envelope family member 4
SYT5 synaptotagmin V
SYTL2 synaptotagmin-like 2
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TDP2 tyrosyl-DNA phosphodiesterase 2
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TGIF1 TGFB-induced factor homeobox 1
TGM5 transglutaminase 5
THAP1 THAP domain containing, apoptosis associated protein 1
TM4SF19 transmembrane 4 L six family member 19
TMEM134 transmembrane protein 134
TMEM14C transmembrane protein 14C
TMEM61 transmembrane protein 61
TMPRSS3 transmembrane protease, serine 3
TP53BP1 tumor protein p53 binding protein 1
TPD52L1 tumor protein D52-like 1
TRIM38 tripartite motif containing 38
TRIM39 tripartite motif containing 39
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TSPAN15 tetraspanin 15
TSPO2 translocator protein 2
TTC3 tetratricopeptide repeat domain 3
TYMS thymidylate synthetase
UBXN10 UBX domain protein 10
UNC5CL unc-5 homolog C (C. elegans)-like
VANGL1 VANGL planar cell polarity protein 1
VN1R5 vomeronasal 1 receptor 5 (gene/pseudogene)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WNK2 WNK lysine deficient protein kinase 2
XXYLT1 xyloside xylosyltransferase 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YPEL4 yippee-like 4 (Drosophila)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF257 zinc finger protein 257
ZNF460 zinc finger protein 460
ZNF534 zinc finger protein 534
ZNF702P zinc finger protein 702, pseudogene
ZNF705A zinc finger protein 705A
ZNF705D zinc finger protein 705D
ZYG11B zyg-11 family member B, cell cycle regulator

low expression

Symbol Name
DGCR8 DGCR8 microprocessor complex subunit
EIF1AD eukaryotic translation initiation factor 1A domain containing