Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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346 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADCY5 adenylate cyclase 5
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AFF3 AF4/FMR2 family, member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPS alkylglycerone phosphate synthase
AHCYL2 adenosylhomocysteinase-like 2
AKIRIN1 akirin 1
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANAPC1 anaphase promoting complex subunit 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APIP APAF1 interacting protein
APOC1 apolipoprotein C-I
APOC1P1 apolipoprotein C-I pseudogene 1
APOC2 apolipoprotein C-II
APOC4 apolipoprotein C-IV
APOE apolipoprotein E
AQP12A aquaporin 12A
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARL1 ADP-ribosylation factor-like 1
ARMT1 acidic residue methyltransferase 1
ASB7 ankyrin repeat and SOCS box containing 7
ASB9 ankyrin repeat and SOCS box containing 9
ASTL astacin-like metallo-endopeptidase (M12 family)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BAG5 BCL2-associated athanogene 5
BBX bobby sox homolog (Drosophila)
BEND3 BEN domain containing 3
BHLHE41 basic helix-loop-helix family, member e41
BHMT2 betaine--homocysteine S-methyltransferase 2
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC6 baculoviral IAP repeat containing 6
BLM Bloom syndrome, RecQ helicase-like
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BMP2K BMP2 inducible kinase
BRAP BRCA1 associated protein
C10ORF82 chromosome 10 open reading frame 82
C14ORF39 chromosome 14 open reading frame 39
C1S complement component 1, s subcomponent
C2 complement component 2
C3ORF17 chromosome 3 open reading frame 17
C3ORF30 chromosome 3 open reading frame 30
C7ORF61 chromosome 7 open reading frame 61
CA5B carbonic anhydrase VB, mitochondrial
CALCA calcitonin-related polypeptide alpha
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CCDC27 coiled-coil domain containing 27
CCNC cyclin C
CCNI cyclin I
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD47 CD47 molecule
CD5L CD5 molecule-like
CDV3 CDV3 homolog (mouse)
CELA2B chymotrypsin-like elastase family, member 2B
CEP135 centrosomal protein 135kDa
CHD4 chromodomain helicase DNA binding protein 4
CLCN5 chloride channel, voltage-sensitive 5
CLDN20 claudin 20
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNOT7 CCR4-NOT transcription complex, subunit 7
COMMD9 COMM domain containing 9
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COX19 COX19 cytochrome c oxidase assembly factor
CPA2 carboxypeptidase A2 (pancreatic)
CRTC3 CREB regulated transcription coactivator 3
CRX cone-rod homeobox
CUL1 cullin 1
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
DAO D-amino-acid oxidase
DCAF4 DDB1 and CUL4 associated factor 4
DCDC2 doublecortin domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DERA deoxyribose-phosphate aldolase (putative)
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1
DICER1 dicer 1, ribonuclease type III
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DOC2A double C2-like domains, alpha
DPEP1 dipeptidase 1 (renal)
DSCR9 Down syndrome critical region 9 (non-protein coding)
DSG2 desmoglein 2
DSPP dentin sialophosphoprotein
DZIP3 DAZ interacting zinc finger protein 3
ECHDC1 ethylmalonyl-CoA decarboxylase 1
ECT2 epithelial cell transforming 2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4E1B eukaryotic translation initiation factor 4E family member 1B
EIF5 eukaryotic translation initiation factor 5
ENOPH1 enolase-phosphatase 1
EPHX4 epoxide hydrolase 4
ERC1 ELKS/RAB6-interacting/CAST family member 1
EWSAT1 Ewing sarcoma associated transcript 1
EXOC5 exocyst complex component 5
FAM102B family with sequence similarity 102, member B
FAM199X family with sequence similarity 199, X-linked
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM46D family with sequence similarity 46, member D
FBXO33 F-box protein 33
FEM1B fem-1 homolog b (C. elegans)
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FNTB farnesyltransferase, CAAX box, beta
FTCD formimidoyltransferase cyclodeaminase
FYTTD1 forty-two-three domain containing 1
GAS2L3 growth arrest-specific 2 like 3
GLB1L2 galactosidase, beta 1-like 2
GLCE glucuronic acid epimerase
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GPR27 G protein-coupled receptor 27
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTSE1 G-2 and S-phase expressed 1
GUCY2GP guanylate cyclase 2G, pseudogene
GYG2 glycogenin 2
HBS1L HBS1-like translational GTPase
HHIPL1 HHIP-like 1
HINT3 histidine triad nucleotide binding protein 3
HIPK2 homeodomain interacting protein kinase 2
HLA-G major histocompatibility complex, class I, G
HOOK1 hook microtubule-tethering protein 1
HOXD12 homeobox D12
HPS3 Hermansky-Pudlak syndrome 3
HPVC1 human papillomavirus (type 18) E5 central sequence-like 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HYALP1 hyaluronoglucosaminidase pseudogene 1
IFT57 intraflagellar transport 57
IL3 interleukin 3
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IREB2 iron-responsive element binding protein 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDM5C lysine (K)-specific demethylase 5C
KDM6A lysine (K)-specific demethylase 6A
KIAA1524 KIAA1524
KIF23 kinesin family member 23
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KLRG2 killer cell lectin-like receptor subfamily G, member 2
KRT8 keratin 8, type II
L3MBTL4 l(3)mbt-like 4 (Drosophila)
LARP4 La ribonucleoprotein domain family, member 4
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LHX6 LIM homeobox 6
LIMS3-LOC440895 LIMS3-LOC440895 readthrough
LIN28A lin-28 homolog A (C. elegans)
LINC00593 long intergenic non-protein coding RNA 593
LINS lines homolog (Drosophila)
LOC283332 uncharacterized LOC283332
LOC285740 uncharacterized LOC285740
LOC653653 adaptor-related protein complex 1, sigma 2 subunit pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRC3 leucine rich repeat containing 3
LZIC leucine zipper and CTNNBIP1 domain containing
MAP10 microtubule-associated protein 10
MAPK10 mitogen-activated protein kinase 10
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MEF2A myocyte enhancer factor 2A
MET MET proto-oncogene, receptor tyrosine kinase
METTL2B methyltransferase like 2B
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIS18BP1 MIS18 binding protein 1
MITF microphthalmia-associated transcription factor
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MOSPD1 motile sperm domain containing 1
MPDZ multiple PDZ domain protein
MPZ myelin protein zero
MSI1 musashi RNA-binding protein 1
MTF2 metal response element binding transcription factor 2
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NADK NAD kinase
NGRN neugrin, neurite outgrowth associated
NHSL2 NHS-like 2
NKX3-1 NK3 homeobox 1
NPFFR1 neuropeptide FF receptor 1
NPHP4 nephronophthisis 4
NPSR1 neuropeptide S receptor 1
NRROS negative regulator of reactive oxygen species
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NUP205 nucleoporin 205kDa
OR11H6 olfactory receptor, family 11, subfamily H, member 6
OR2A5 olfactory receptor, family 2, subfamily A, member 5
OR5W2 olfactory receptor, family 5, subfamily W, member 2
OR6B3 olfactory receptor, family 6, subfamily B, member 3
OR6K2 olfactory receptor, family 6, subfamily K, member 2
OR7E5P olfactory receptor, family 7, subfamily E, member 5 pseudogene
OSBPL8 oxysterol binding protein-like 8
PADI3 peptidyl arginine deiminase, type III
PAPOLA poly(A) polymerase alpha
PAQR5 progestin and adipoQ receptor family member V
PARPBP PARP1 binding protein
PCDHGB7 protocadherin gamma subfamily B, 7
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDHX pyruvate dehydrogenase complex, component X
PIAS1 protein inhibitor of activated STAT, 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PITPNB phosphatidylinositol transfer protein, beta
PKP4 plakophilin 4
PLXNA1 plexin A1
PLXNC1 plexin C1
PLXND1 plexin D1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNLIPRP2 pancreatic lipase-related protein 2
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPARA peroxisome proliferator-activated receptor alpha
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRC1 protein regulator of cytokinesis 1
PRKG2 protein kinase, cGMP-dependent, type II
PRTG protogenin
PSKH2 protein serine kinase H2
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
RAB11A RAB11A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD23B RAD23 homolog B (S. cerevisiae)
RANBP2 RAN binding protein 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBM38 RNA binding motif protein 38
RCCD1 RCC1 domain containing 1
RCOR1 REST corepressor 1
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RHEB Ras homolog enriched in brain
RLIM ring finger protein, LIM domain interacting
ROPN1 rhophilin associated tail protein 1
RP1L1 retinitis pigmentosa 1-like 1
RPL4 ribosomal protein L4
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas)
RXFP4 relaxin/insulin-like family peptide receptor 4
RXRA retinoid X receptor, alpha
RYBP RING1 and YY1 binding protein
SARDH sarcosine dehydrogenase
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAF8 SR-related CTD-associated factor 8
SCAPER S-phase cyclin A-associated protein in the ER
SEC16A SEC16 homolog A (S. cerevisiae)
SEPT11 septin 11
SERAC1 serine active site containing 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD8 SET domain containing (lysine methyltransferase) 8
SETX senataxin
SHE Src homology 2 domain containing E
SHISA2 shisa family member 2
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SHROOM2 shroom family member 2
SI sucrase-isomaltase (alpha-glucosidase)
SIN3A SIN3 transcription regulator family member A
SLC18B1 solute carrier family 18, subfamily B, member 1
SLC25A47 solute carrier family 25, member 47
SLC30A6 solute carrier family 30 (zinc transporter), member 6
SLC37A3 solute carrier family 37, member 3
SLC38A1 solute carrier family 38, member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SMIM24 small integral membrane protein 24
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNORA24 small nucleolar RNA, H/ACA box 24
SNORA45B small nucleolar RNA, H/ACA box 45B
SNORA79 small nucleolar RNA, H/ACA box 79
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPATA13 spermatogenesis associated 13
SPESP1 sperm equatorial segment protein 1
SSH1 slingshot protein phosphatase 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT1 signal transducer and activator of transcription 1, 91kDa
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SURF4 surfeit 4
SUSD2 sushi domain containing 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TDRD9 tudor domain containing 9
TFF3 trefoil factor 3 (intestinal)
THAP10 THAP domain containing 10
THRAP3 thyroid hormone receptor associated protein 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM165 transmembrane protein 165
TMEM181 transmembrane protein 181
TMEM237 transmembrane protein 237
TMEM263 transmembrane protein 263
TMX1 thioredoxin-related transmembrane protein 1
TNPO3 transportin 3
TPD52L1 tumor protein D52-like 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC3L trafficking protein particle complex 3-like
TRIM44 tripartite motif containing 44
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSN translin
TTK TTK protein kinase
TULP4 tubby like protein 4
TXLNG taxilin gamma
UBE3C ubiquitin protein ligase E3C
UBL3 ubiquitin-like 3
UBXN10 UBX domain protein 10
UNC45A unc-45 homolog A (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
URI1 URI1, prefoldin-like chaperone
USP51 ubiquitin specific peptidase 51
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VWA9 von Willebrand factor A domain containing 9
WASL Wiskott-Aldrich syndrome-like
WDR5 WD repeat domain 5
WNK3 WNK lysine deficient protein kinase 3
WWC3 WWC family member 3
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XPO4 exportin 4
ZBTB2 zinc finger and BTB domain containing 2
ZBTB24 zinc finger and BTB domain containing 24
ZBTB43 zinc finger and BTB domain containing 43
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFX zinc finger protein, X-linked
ZFYVE9 zinc finger, FYVE domain containing 9
ZIC4 Zic family member 4
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF12 zinc finger protein 12
ZNF229 zinc finger protein 229
ZNF267 zinc finger protein 267
ZNF268 zinc finger protein 268
ZNF280A zinc finger protein 280A
ZNF295-AS1 ZNF295 antisense RNA 1
ZNF407 zinc finger protein 407
ZNF410 zinc finger protein 410
ZNF516 zinc finger protein 516
ZNF541 zinc finger protein 541
ZNF710 zinc finger protein 710
ZNF761 zinc finger protein 761
ZNF813 zinc finger protein 813
ZWILCH zwilch kinetochore protein