Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
Similar Terms
Downloads & Tools


342 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
ACYP2 acylphosphatase 2, muscle type
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY1 adenylate cyclase 1 (brain)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRB2 adhesion G protein-coupled receptor B2
ADIG adipogenin
ADPRH ADP-ribosylarginine hydrolase
AIM1 absent in melanoma 1
ALLC allantoicase
ANKRD6 ankyrin repeat domain 6
ANXA1 annexin A1
ANXA4 annexin A4
AQP8 aquaporin 8
ARHGAP21 Rho GTPase activating protein 21
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33
ARMC9 armadillo repeat containing 9
ARSJ arylsulfatase family, member J
ASPA aspartoacylase
ASTN2 astrotactin 2
ATRN attractin
ATRNL1 attractin-like 1
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
B9D1 B9 protein domain 1
BBS12 Bardet-Biedl syndrome 12
BCAR1 breast cancer anti-estrogen resistance 1
BMP15 bone morphogenetic protein 15
BMP8A bone morphogenetic protein 8a
BMPR1B bone morphogenetic protein receptor, type IB
BOC BOC cell adhesion associated, oncogene regulated
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C15ORF52 chromosome 15 open reading frame 52
C16ORF86 chromosome 16 open reading frame 86
C17ORF64 chromosome 17 open reading frame 64
C19ORF35 chromosome 19 open reading frame 35
C1ORF216 chromosome 1 open reading frame 216
C5ORF15 chromosome 5 open reading frame 15
C9ORF3 chromosome 9 open reading frame 3
C9ORF50 chromosome 9 open reading frame 50
CALHM1 calcium homeostasis modulator 1
CBR1 carbonyl reductase 1
CC2D1A coiled-coil and C2 domain containing 1A
CCDC158 coiled-coil domain containing 158
CCDC7 coiled-coil domain containing 7
CCKBR cholecystokinin B receptor
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC14B cell division cycle 14B
CDC14C cell division cycle 14C
CDKN2B-AS1 CDKN2B antisense RNA 1
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding)
CELP carboxyl ester lipase pseudogene
CFAP20 cilia and flagella associated protein 20
CHDH choline dehydrogenase
CHUK conserved helix-loop-helix ubiquitous kinase
CIAO1 cytosolic iron-sulfur assembly component 1
CMYA5 cardiomyopathy associated 5
COA3 cytochrome c oxidase assembly factor 3
COMMD3 COMM domain containing 3
COPZ2 coatomer protein complex, subunit zeta 2
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPNE5 copine V
CRYM crystallin, mu
CST1 cystatin SN
CST4 cystatin S
CTHRC1 collagen triple helix repeat containing 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CUTC cutC copper transporter
CXXC5 CXXC finger protein 5
CYB5D2 cytochrome b5 domain containing 2
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAKD dephospho-CoA kinase domain containing
DDO D-aspartate oxidase
DHRS11 dehydrogenase/reductase (SDR family) member 11
DKFZP779M0652 uncharacterized DKFZp779M0652
DNAH9 dynein, axonemal, heavy chain 9
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRC1 dynein regulatory complex subunit 1
DYNLL2 dynein, light chain, LC8-type 2
DZIP1L DAZ interacting zinc finger protein 1-like
EFCAB3 EF-hand calcium binding domain 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EMC8 ER membrane protein complex subunit 8
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
EPDR1 ependymin related 1
ERLIN1 ER lipid raft associated 1
ESR1 estrogen receptor 1
ESYT2 extended synaptotagmin-like protein 2
EXTL1 exostosin-like glycosyltransferase 1
FAIM Fas apoptotic inhibitory molecule
FAM138E family with sequence similarity 138, member E
FAM180B family with sequence similarity 180, member B
FAM183A family with sequence similarity 183, member A
FAM185A family with sequence similarity 185, member A
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM225A family with sequence similarity 225, member A (non-protein coding)
FAM225B family with sequence similarity 225, member B (non-protein coding)
FAM47E family with sequence similarity 47, member E
FAM86DP family with sequence similarity 86, member D, pseudogene
FAP fibroblast activation protein, alpha
FBXO44 F-box protein 44
FBXW4 F-box and WD repeat domain containing 4
FGF1 fibroblast growth factor 1 (acidic)
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOLR1 folate receptor 1 (adult)
FRMPD2B FERM and PDZ domain containing 2B, pseudogene
FUCA2 fucosidase, alpha-L- 2, plasma
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GEMIN8P4 gem (nuclear organelle) associated protein 8 pseudogene 4
GJB1 gap junction protein, beta 1, 32kDa
GLOD4 glyoxalase domain containing 4
GLT8D1 glycosyltransferase 8 domain containing 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR155 G protein-coupled receptor 155
GRB10 growth factor receptor-bound protein 10
GSAP gamma-secretase activating protein
GSN gelsolin
GUCA1B guanylate cyclase activator 1B (retina)
HABP4 hyaluronan binding protein 4
HCG9 HLA complex group 9 (non-protein coding)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA10 homeobox A10
HOXA4 homeobox A4
HPS1 Hermansky-Pudlak syndrome 1
HSPA12A heat shock 70kDa protein 12A
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IDUA iduronidase, alpha-L-
IL27RA interleukin 27 receptor, alpha
IRAK3 interleukin-1 receptor-associated kinase 3
IRX1 iroquois homeobox 1
ITGA6 integrin, alpha 6
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCTD10 potassium channel tetramerization domain containing 10
KIAA0513 KIAA0513
KIAA1549L KIAA1549-like
KIFC3 kinesin family member C3
KLC1 kinesin light chain 1
KLF14 Kruppel-like factor 14
KLHL30 kelch-like family member 30
KLHL36 kelch-like family member 36
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRCC1 lysine-rich coiled-coil 1
L3MBTL4 l(3)mbt-like 4 (Drosophila)
LCTL lactase-like
LGSN lengsin, lens protein with glutamine synthetase domain
LINC00244 long intergenic non-protein coding RNA 244
LINC00341 long intergenic non-protein coding RNA 341
LINC00852 long intergenic non-protein coding RNA 852
LINGO1 leucine rich repeat and Ig domain containing 1
LINGO2 leucine rich repeat and Ig domain containing 2
LMF1 lipase maturation factor 1
LOC113230 uncharacterized protein LOC113230
LOH12CR2 loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
LOXL3 lysyl oxidase-like 3
LRP11 low density lipoprotein receptor-related protein 11
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC75A leucine rich repeat containing 75A
LRRC8D leucine rich repeat containing 8 family, member D
LZTS2 leucine zipper, putative tumor suppressor 2
M1AP meiosis 1 associated protein
MACF1 microtubule-actin crosslinking factor 1
MAGED2 melanoma antigen family D2
MAN1B1 mannosidase, alpha, class 1B, member 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARCH5 membrane-associated ring finger (C3HC4) 5
MARVELD1 MARVEL domain containing 1
MATN2 matrilin 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MEF2A myocyte enhancer factor 2A
MEGF9 multiple EGF-like-domains 9
MIA melanoma inhibitory activity
MILR1 mast cell immunoglobulin-like receptor 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLYCD malonyl-CoA decarboxylase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP27 matrix metallopeptidase 27
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MORN4 MORN repeat containing 4
MPG N-methylpurine-DNA glycosylase
MPZ myelin protein zero
MRAS muscle RAS oncogene homolog
MREG melanoregulin
MRO maestro
MRPL43 mitochondrial ribosomal protein L43
MRPS6 mitochondrial ribosomal protein S6
MSX1 msh homeobox 1
MTFR1L mitochondrial fission regulator 1-like
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYOF myoferlin
NACAD NAC alpha domain containing
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NKX2-5 NK2 homeobox 5
NKX3-2 NK3 homeobox 2
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NRXN3 neurexin 3
ODF1 outer dense fiber of sperm tails 1
OLMALINC oligodendrocyte maturation-associated long intergenic non-coding RNA
OR4F5 olfactory receptor, family 4, subfamily F, member 5
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAGE5 P antigen family, member 5 (prostate associated)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARD6G par-6 family cell polarity regulator gamma
PAX4 paired box 4
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PCDHGC3 protocadherin gamma subfamily C, 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDLIM4 PDZ and LIM domain 4
PDZD7 PDZ domain containing 7
PFN4 profilin family, member 4
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLXNB3 plexin B3
PMP2 peripheral myelin protein 2
PMP22 peripheral myelin protein 22
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PON2 paraoxonase 2
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP3R2 protein phosphatase 3, regulatory subunit B, beta
PQLC3 PQ loop repeat containing 3
PREP prolyl endopeptidase
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSPH phosphoserine phosphatase
PTCH1 patched 1
QDPR quinoid dihydropteridine reductase
RAB18 RAB18, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
REP15 RAB15 effector protein
RGS11 regulator of G-protein signaling 11
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIMBP3C RIMS binding protein 3C
RNF215 ring finger protein 215
RNF32 ring finger protein 32
RTKN rhotekin
RXRG retinoid X receptor, gamma
S100A4 S100 calcium binding protein A4
S100B S100 calcium binding protein B
SAP30 Sin3A-associated protein, 30kDa
SASH1 SAM and SH3 domain containing 1
SCARB2 scavenger receptor class B, member 2
SCFD2 sec1 family domain containing 2
SCML4 sex comb on midleg-like 4 (Drosophila)
SCRG1 stimulator of chondrogenesis 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFXN3 sideroflexin 3
SGCE sarcoglycan, epsilon
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC25A47 solute carrier family 25, member 47
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35G1 solute carrier family 35, member G1
SLC35G2 solute carrier family 35, member G2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOBP sine oculis binding protein homolog (Drosophila)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPHK2 sphingosine kinase 2
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STBD1 starch binding domain 1
SUMF1 sulfatase modifying factor 1
SUMF2 sulfatase modifying factor 2
SUSD1 sushi domain containing 1
TBC1D10A TBC1 domain family, member 10A
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL3 transcription elongation factor A (SII)-like 3
TCEAL4 transcription elongation factor A (SII)-like 4
TCEAL5 transcription elongation factor A (SII)-like 5
TCEAL6 transcription elongation factor A (SII)-like 6
TCTA T-cell leukemia translocation altered
TCTN3 tectonic family member 3
TEF thyrotrophic embryonic factor
TEX12 testis expressed 12
TGFBR1 transforming growth factor, beta receptor 1
TGM4 transglutaminase 4
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TIAM1 T-cell lymphoma invasion and metastasis 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM9SF3 transmembrane 9 superfamily member 3
TMEM121 transmembrane protein 121
TMEM17 transmembrane protein 17
TMEM229B transmembrane protein 229B
TMSB4Y thymosin beta 4, Y-linked
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNC tenascin C
TP53I3 tumor protein p53 inducible protein 3
TPST1 tyrosylprotein sulfotransferase 1
TRIM74 tripartite motif containing 74
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRUB2 TruB pseudouridine (psi) synthase family member 2
TTLL13P tubulin tyrosine ligase-like family member 13, pseudogene
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TUBB2A tubulin, beta 2A class IIa
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBTD1 ubiquitin domain containing 1
UFSP2 UFM1-specific peptidase 2
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UIMC1 ubiquitin interaction motif containing 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
ZDHHC16 zinc finger, DHHC-type containing 16
ZDHHC7 zinc finger, DHHC-type containing 7
ZFYVE27 zinc finger, FYVE domain containing 27
ZMYND12 zinc finger, MYND-type containing 12
ZNF287 zinc finger protein 287
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZSWIM7 zinc finger, SWIM-type containing 7

low expression

Symbol Name
BRAP BRCA1 associated protein
CCSER2 coiled-coil serine-rich protein 2
FAM35A family with sequence similarity 35, member A
FAM35BP family with sequence similarity 35, member A pseudogene
GHITM growth hormone inducible transmembrane protein
GLUD1 glutamate dehydrogenase 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
MBD1 methyl-CpG binding domain protein 1
PCBP2 poly(rC) binding protein 2
PUM1 pumilio RNA-binding family member 1
RNF10 ring finger protein 10
TMBIM6 transmembrane BAX inhibitor motif containing 6