Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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276 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29E-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABHD6 abhydrolase domain containing 6
ACTL10 actin-like 10
ADAM32 ADAM metallopeptidase domain 32
ADORA2B adenosine A2b receptor
AGA aspartylglucosaminidase
AHCYL1 adenosylhomocysteinase-like 1
AK7 adenylate kinase 7
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
AMT aminomethyltransferase
ANTXR1 anthrax toxin receptor 1
AOX2P aldehyde oxidase 2 pseudogene
AP4B1 adaptor-related protein complex 4, beta 1 subunit
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATL1 atlastin GTPase 1
ATP13A5 ATPase type 13A5
ATP1A1-AS1 ATP1A1 antisense RNA 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
AUH AU RNA binding protein/enoyl-CoA hydratase
AURKA aurora kinase A
BACE2 beta-site APP-cleaving enzyme 2
BAMBI BMP and activin membrane-bound inhibitor
BEND7 BEN domain containing 7
BRS3 bombesin-like receptor 3
C12ORF60 chromosome 12 open reading frame 60
C17ORF107 chromosome 17 open reading frame 107
C19ORF71 chromosome 19 open reading frame 71
C20ORF24 chromosome 20 open reading frame 24
C8ORF31 chromosome 8 open reading frame 31
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CALCOCO2 calcium binding and coiled-coil domain 2
CCBL2 cysteine conjugate-beta lyase 2
CCDC151 coiled-coil domain containing 151
CDON cell adhesion associated, oncogene regulated
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CHMP1B charged multivesicular body protein 1B
CHMP4B charged multivesicular body protein 4B
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTD2 cyclin N-terminal domain containing 2
COL5A3 collagen, type V, alpha 3
CRLF2 cytokine receptor-like factor 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSA cathepsin A
CTSL cathepsin L
CTTNBP2 cortactin binding protein 2
CUL1 cullin 1
CYSLTR2 cysteinyl leukotriene receptor 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCAF6 DDB1 and CUL4 associated factor 6
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEPDC7 DEP domain containing 7
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLAT dihydrolipoamide S-acetyltransferase
DLD dihydrolipoamide dehydrogenase
DLG5 discs, large homolog 5 (Drosophila)
DLL1 delta-like 1 (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNER delta/notch-like EGF repeat containing
DPP6 dipeptidyl-peptidase 6
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ELP2 elongator acetyltransferase complex subunit 2
EN2 engrailed homeobox 2
ENOSF1 enolase superfamily member 1
FAM101B family with sequence similarity 101, member B
FAM35DP family with sequence similarity 35, member A pseudogene
FAM83D family with sequence similarity 83, member D
FBXL4 F-box and leucine-rich repeat protein 4
FLJ30679 uncharacterized protein FLJ30679
FOXF1 forkhead box F1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FRK fyn-related Src family tyrosine kinase
FSCN2 fascin actin-bundling protein 2, retinal
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAK cyclin G associated kinase
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GIF gastric intrinsic factor (vitamin B synthesis)
GJD4 gap junction protein, delta 4, 40.1kDa
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GLRX2 glutaredoxin 2
GLUD1 glutamate dehydrogenase 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPHN gephyrin
GPR3 G protein-coupled receptor 3
GPR85 G protein-coupled receptor 85
GRSF1 G-rich RNA sequence binding factor 1
GUCA1A guanylate cyclase activator 1A (retina)
GUF1 GUF1 GTPase homolog (S. cerevisiae)
H2AFJ H2A histone family, member J
HACL1 2-hydroxyacyl-CoA lyase 1
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HEATR5A HEAT repeat containing 5A
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HRASLS HRAS-like suppressor
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTRA1 HtrA serine peptidase 1
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
IQGAP2 IQ motif containing GTPase activating protein 2
ISCA1 iron-sulfur cluster assembly 1
ISCA1P1 iron-sulfur cluster assembly 1 pseudogene 1
ITGA7 integrin, alpha 7
KCNK10 potassium channel, two pore domain subfamily K, member 10
KGFLP1 fibroblast growth factor 7 pseudogene
KIF3B kinesin family member 3B
KLF9 Kruppel-like factor 9
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMA1 laminin, alpha 1
LDHC lactate dehydrogenase C
LOC100132111 uncharacterized LOC100132111
LOC284661 uncharacterized LOC284661
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR2 lysophosphatidic acid receptor 2
LRRC2 leucine rich repeat containing 2
LRRC6 leucine rich repeat containing 6
LRRC8D leucine rich repeat containing 8 family, member D
LYPD1 LY6/PLAUR domain containing 1
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator
MCF2 MCF.2 cell line derived transforming sequence
MCTP2 multiple C2 domains, transmembrane 2
MCTS2P malignant T cell amplified sequence 2, pseudogene
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MFSD7 major facilitator superfamily domain containing 7
MGC2889 uncharacterized protein MGC2889
MGST1 microsomal glutathione S-transferase 1
MMD monocyte to macrophage differentiation-associated
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MOCOS molybdenum cofactor sulfurase
MRPS31 mitochondrial ribosomal protein S31
MTCL1 microtubule crosslinking factor 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NDC80 NDC80 kinetochore complex component
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NLRP6 NLR family, pyrin domain containing 6
NNMT nicotinamide N-methyltransferase
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NUP93 nucleoporin 93kDa
NXPH3 neurexophilin 3
OAT ornithine aminotransferase
ONECUT1 one cut homeobox 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR4F21 olfactory receptor, family 4, subfamily F, member 21
OSBPL5 oxysterol binding protein-like 5
OSGIN2 oxidative stress induced growth inhibitor family member 2
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAH phenylalanine hydroxylase
PAM peptidylglycine alpha-amidating monooxygenase
PAPL iron/zinc purple acid phosphatase-like protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAQR3 progestin and adipoQ receptor family member III
PCDHGA3 protocadherin gamma subfamily A, 3
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PF4 platelet factor 4
PF4V1 platelet factor 4 variant 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGM1 phosphoglucomutase 1
PGPEP1L pyroglutamyl-peptidase I-like
PHB prohibitin
PHLDB2 pleckstrin homology-like domain, family B, member 2
PHYH phytanoyl-CoA 2-hydroxylase
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLBD2 phospholipase B domain containing 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRDX3 peroxiredoxin 3
PRSS42 protease, serine, 42
PRUNE2 prune homolog 2 (Drosophila)
PTDSS1 phosphatidylserine synthase 1
PTH2R parathyroid hormone 2 receptor
PTPRU protein tyrosine phosphatase, receptor type, U
QPCTL glutaminyl-peptide cyclotransferase-like
RAB40B RAB40B, member RAS oncogene family
RASD2 RASD family, member 2
RASEF RAS and EF-hand domain containing
RB1 retinoblastoma 1
RBM45 RNA binding motif protein 45
RBM47 RNA binding motif protein 47
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDH8 retinol dehydrogenase 8 (all-trans)
RFK riboflavin kinase
RIPK2 receptor-interacting serine-threonine kinase 2
RPN2 ribophorin II
RTCA RNA 3'-terminal phosphate cyclase
SAMD12 sterile alpha motif domain containing 12
SAMD5 sterile alpha motif domain containing 5
SAR1A secretion associated, Ras related GTPase 1A
SCARA5 scavenger receptor class A, member 5
SCCPDH saccharopine dehydrogenase (putative)
SCYL1 SCY1-like 1 (S. cerevisiae)
SDF4 stromal cell derived factor 4
SETD3 SET domain containing 3
SFT2D2 SFT2 domain containing 2
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
SHCBP1 SHC SH2-domain binding protein 1
SIAE sialic acid acetylesterase
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLAIN1 SLAIN motif family, member 1
SLC16A6 solute carrier family 16, member 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35B1 solute carrier family 35, member B1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMAD2 SMAD family member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNF8 SNF8, ESCRT-II complex subunit
SPHK1 sphingosine kinase 1
SPON2 spondin 2, extracellular matrix protein
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STRIP2 striatin interacting protein 2
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SURF4 surfeit 4
SYCE3 synaptonemal complex central element protein 3
SYT5 synaptotagmin V
TBX19 T-box 19
TCTN3 tectonic family member 3
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2
THEMIS2 thymocyte selection associated family member 2
TIGD2 tigger transposable element derived 2
TLDC2 TBC/LysM-associated domain containing 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM132D transmembrane protein 132D
TMEM169 transmembrane protein 169
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TMEM233 transmembrane protein 233
TMEM71 transmembrane protein 71
TNPO2 transportin 2
TOMM34 translocase of outer mitochondrial membrane 34
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPCN1 two pore segment channel 1
TPX2 TPX2, microtubule-associated
TRIM62 tripartite motif containing 62
TTTY5 testis-specific transcript, Y-linked 5 (non-protein coding)
UBE2Z ubiquitin-conjugating enzyme E2Z
USP27X ubiquitin specific peptidase 27, X-linked
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VAMP4 vesicle-associated membrane protein 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WIPI1 WD repeat domain, phosphoinositide interacting 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZKSCAN2 zinc finger with KRAB and SCAN domains 2
ZNF652 zinc finger protein 652
ZNF823 zinc finger protein 823

low expression

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
CUL4B cullin 4B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
UBAC2 UBA domain containing 2