Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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366 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AACSP1 acetoacetyl-CoA synthetase pseudogene 1
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABHD6 abhydrolase domain containing 6
ACAA1 acetyl-CoA acyltransferase 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACTN1 actinin, alpha 1
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR1 activin A receptor, type I
ACY1 aminoacylase 1
ADAM30 ADAM metallopeptidase domain 30
AGA aspartylglucosaminidase
AGO2 argonaute RISC catalytic component 2
AHNAK AHNAK nucleoprotein
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALMS1P Alstrom syndrome 1 pseudogene
AMBRA1 autophagy/beclin-1 regulator 1
AMDHD2 amidohydrolase domain containing 2
AMOT angiomotin
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANXA3 annexin A3
APEH acylaminoacyl-peptide hydrolase
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
APOOL apolipoprotein O-like
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
APTX aprataxin
ARF4 ADP-ribosylation factor 4
ARHGAP17 Rho GTPase activating protein 17
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASB6 ankyrin repeat and SOCS box containing 6
ASRGL1 asparaginase like 1
ATAD3B ATPase family, AAA domain containing 3B
ATOX1 antioxidant 1 copper chaperone
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATRIP ATR interacting protein
ATXN7 ataxin 7
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAIAP2L1 BAI1-associated protein 2-like 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEST1 bestrophin 1
BHLHE41 basic helix-loop-helix family, member e41
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BPIFB1 BPI fold containing family B, member 1
BPIFB2 BPI fold containing family B, member 2
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BRPF1 bromodomain and PHD finger containing, 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF31 chromosome 11 open reading frame 31
C14ORF169 chromosome 14 open reading frame 169
C1ORF226 chromosome 1 open reading frame 226
C20ORF173 chromosome 20 open reading frame 173
C3ORF14 chromosome 3 open reading frame 14
C3ORF38 chromosome 3 open reading frame 38
C9ORF114 chromosome 9 open reading frame 114
C9ORF91 chromosome 9 open reading frame 91
CA8 carbonic anhydrase VIII
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBWD3 COBW domain containing 3
CCDC66 coiled-coil domain containing 66
CCDC79 coiled-coil domain containing 79
CCNJL cyclin J-like
CD5L CD5 molecule-like
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH7 cadherin 7, type 2
CDK2 cyclin-dependent kinase 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLCN3 chloride channel, voltage-sensitive 3
CPA2 carboxypeptidase A2 (pancreatic)
CPT2 carnitine palmitoyltransferase 2
CREBL2 cAMP responsive element binding protein-like 2
CROCC ciliary rootlet coiled-coil, rootletin
CST2 cystatin SA
CST5 cystatin D
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL1 cullin 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXORF65 chromosome X open reading frame 65
DCP1A decapping mRNA 1A
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DENND6A DENN/MADD domain containing 6A
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DUSP7 dual specificity phosphatase 7
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
ERC1 ELKS/RAB6-interacting/CAST family member 1
EXOSC7 exosome component 7
FADS3 fatty acid desaturase 3
FAM102B family with sequence similarity 102, member B
FAM120AOS family with sequence similarity 120A opposite strand
FAM167B family with sequence similarity 167, member B
FAM208A family with sequence similarity 208, member A
FAM219A family with sequence similarity 219, member A
FAM86DP family with sequence similarity 86, member D, pseudogene
FASN fatty acid synthase
FAXC failed axon connections homolog (Drosophila)
FER fer (fps/fes related) tyrosine kinase
FOCAD focadhesin
FOXO4 forkhead box O4
FRMD4B FERM domain containing 4B
FSTL5 follistatin-like 5
FTH1 ferritin, heavy polypeptide 1
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
FYCO1 FYVE and coiled-coil domain containing 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GATSL2 GATS protein-like 2
GJB1 gap junction protein, beta 1, 32kDa
GLT8D1 glycosyltransferase 8 domain containing 1
GLYCTK glycerate kinase
GMPPB GDP-mannose pyrophosphorylase B
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA4 golgin A4
GXYLT2 glucoside xylosyltransferase 2
GYG2 glycogenin 2
HEMK1 HemK methyltransferase family member 1
HHAT hedgehog acyltransferase
HIATL2 hippocampus abundant transcript-like 2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIST1H2AD histone cluster 1, H2ad
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2BJ histone cluster 1, H2bj
HIST1H3D histone cluster 1, H3d
HIST1H3G histone cluster 1, H3g
HIST2H2BF histone cluster 2, H2bf
HIST2H4A histone cluster 2, H4a
HLA-G major histocompatibility complex, class I, G
HNF1A-AS1 HNF1A antisense RNA 1
HRH2 histamine receptor H2
HRK harakiri, BCL2 interacting protein
HSPA4 heat shock 70kDa protein 4
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IER5L immediate early response 5-like
IFRD2 interferon-related developmental regulator 2
IL17RC interleukin 17 receptor C
INSL4 insulin-like 4 (placenta)
ITLN2 intelectin 2
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KCTD14 potassium channel tetramerization domain containing 14
KCTD6 potassium channel tetramerization domain containing 6
KLC1 kinesin light chain 1
KLHL9 kelch-like family member 9
KRT18 keratin 18, type I
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCMT2 leucine carboxyl methyltransferase 2
LDHAL6B lactate dehydrogenase A-like 6B
LINC00235 long intergenic non-protein coding RNA 235
LOC340357 uncharacterized LOC340357
LOC374443 C-type lectin domain family 2, member D pseudogene
LOC641367 cyclin Y-like 1 pseudogene
LPO lactoperoxidase
LPXN leupaxin
LRRN4CL LRRN4 C-terminal like
LSG1 large 60S subunit nuclear export GTPase 1
LSR lipolysis stimulated lipoprotein receptor
LURAP1 leucine rich adaptor protein 1
LY6E lymphocyte antigen 6 complex, locus E
LYPD1 LY6/PLAUR domain containing 1
MAGEB6 melanoma antigen family B6
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP6D1 MAP6 domain containing 1
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MESTIT1 MEST intronic transcript 1, antisense RNA
MFSD3 major facilitator superfamily domain containing 3
MGAM maltase-glucoamylase
MID1 midline 1
MLANA melan-A
MLIP muscular LMNA-interacting protein
MORF4 mortality factor 4 (pseudogene)
MRPS25 mitochondrial ribosomal protein S25
MRRF mitochondrial ribosome recycling factor
MSANTD3 Myb/SANT-like DNA-binding domain containing 3
MTMR14 myotubularin related protein 14
MYEOV myeloma overexpressed
MYO1E myosin IE
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCKIPSD NCK interacting protein with SH3 domain
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NEK10 NIMA-related kinase 10
NEK4 NIMA-related kinase 4
NKX3-1 NK3 homeobox 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOL9 nucleolar protein 9
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPPC natriuretic peptide C
NUP188 nucleoporin 188kDa
OARD1 O-acyl-ADP-ribose deacylase 1
OMP olfactory marker protein
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OTUD7A OTU deubiquitinase 7A
OXNAD1 oxidoreductase NAD-binding domain containing 1
PBDC1 polysaccharide biosynthesis domain containing 1
PBRM1 polybromo 1
PCDHGA8 protocadherin gamma subfamily A, 8
PDE12 phosphodiesterase 12
PDHB pyruvate dehydrogenase (lipoamide) beta
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHF7 PHD finger protein 7
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G16 phospholipase A2, group XVI
PLEC plectin
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PNPLA4 patatin-like phospholipase domain containing 4
POC1A POC1 centriolar protein A
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POMK protein-O-mannose kinase
PP2D1 protein phosphatase 2C-like domain containing 1
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP4R2 protein phosphatase 4, regulatory subunit 2
PQLC2 PQ loop repeat containing 2
PRB3 proline-rich protein BstNI subfamily 3
PRB4 proline-rich protein BstNI subfamily 4
PRDX1 peroxiredoxin 1
PRH1 proline-rich protein HaeIII subfamily 1
PRH2 proline-rich protein HaeIII subfamily 2
PRKCD protein kinase C, delta
PRM1 protamine 1
PROM1 prominin 1
PSCA prostate stem cell antigen
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PTBP2 polypyrimidine tract binding protein 2
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRU protein tyrosine phosphatase, receptor type, U
PXK PX domain containing serine/threonine kinase
RAB17 RAB17, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP10 RAN binding protein 10
RBM15B RNA binding motif protein 15B
RBM19 RNA binding motif protein 19
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RFT1 RFT1 homolog (S. cerevisiae)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNASEH1 ribonuclease H1
RPH3A rabphilin 3A
RPL29 ribosomal protein L29
RPP14 ribonuclease P/MRP 14kDa subunit
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPUSD3 RNA pseudouridylate synthase domain containing 3
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RSC1A1 regulatory solute carrier protein, family 1, member 1
RYBP RING1 and YY1 binding protein
SCGB3A1 secretoglobin, family 3A, member 1
SEC13 SEC13 homolog (S. cerevisiae)
SETD1B SET domain containing 1B
SETD5 SET domain containing 5
SFMBT1 Scm-like with four mbt domains 1
SHF Src homology 2 domain containing F
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SLAMF7 SLAM family member 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35G1 solute carrier family 35, member G1
SLC37A3 solute carrier family 37, member 3
SLC38A7 solute carrier family 38, member 7
SLC43A3 solute carrier family 43, member 3
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLMAP sarcolemma associated protein
SNORA59B small nucleolar RNA, H/ACA box 59B
SPATA18 spermatogenesis associated 18
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPNS1 spinster homolog 1 (Drosophila)
SQSTM1 sequestosome 1
STRADB STE20-related kinase adaptor beta
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX3 syntaxin 3
STXBP1 syntaxin binding protein 1
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SYT14 synaptotagmin XIV
SYTL2 synaptotagmin-like 2
SZT2 seizure threshold 2 homolog (mouse)
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TCTA T-cell leukemia translocation altered
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TEX264 testis expressed 264
THEM6 thioesterase superfamily member 6
THOC7 THO complex 7
TKT transketolase
TLR4 toll-like receptor 4
TLX3 T-cell leukemia homeobox 3
TMED8 transmembrane emp24 protein transport domain containing 8
TMEM106C transmembrane protein 106C
TMEM110 transmembrane protein 110
TMEM194B transmembrane protein 194B
TMEM215 transmembrane protein 215
TMEM251 transmembrane protein 251
TMF1 TATA element modulatory factor 1
TMPPE transmembrane protein with metallophosphoesterase domain
TNPO1 transportin 1
TPD52 tumor protein D52
TRIM33 tripartite motif containing 33
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIOBP TRIO and F-actin binding protein
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSN translin
TSPAN10 tetraspanin 10
TSPO2 translocator protein 2
TTLL8 tubulin tyrosine ligase-like family member 8
TTYH2 tweety family member 2
TUSC2 tumor suppressor candidate 2
TWF2 twinfilin actin binding protein 2
UBA3 ubiquitin-like modifier activating enzyme 3
UCK1 uridine-cytidine kinase 1
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
ULK4 unc-51 like kinase 4
UNC5CL unc-5 homolog C (C. elegans)-like
USP19 ubiquitin specific peptidase 19
UTS2 urotensin 2
VANGL1 VANGL planar cell polarity protein 1
VGF VGF nerve growth factor inducible
VPRBP Vpr (HIV-1) binding protein
VSIG10 V-set and immunoglobulin domain containing 10
WDR82 WD repeat domain 82
XPC xeroderma pigmentosum, complementation group C
XYLB xylulokinase homolog (H. influenzae)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZDHHC3 zinc finger, DHHC-type containing 3
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF280A zinc finger protein 280A
ZNF398 zinc finger protein 398
ZNF654 zinc finger protein 654
ZNF689 zinc finger protein 689
ZNF717 zinc finger protein 717
ZNF827 zinc finger protein 827
ZNF841 zinc finger protein 841

low expression

Symbol Name
CYTH2 cytohesin 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
WDR59 WD repeat domain 59
ZNF513 zinc finger protein 513