Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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450 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACTR3BP2 ACTR3B pseudogene 2
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ACVR1C activin A receptor, type IC
ADAL adenosine deaminase-like
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADAM22 ADAM metallopeptidase domain 22
ADAM7 ADAM metallopeptidase domain 7
ADGRG2 adhesion G protein-coupled receptor G2
AMZ2 archaelysin family metallopeptidase 2
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
ANKRD6 ankyrin repeat domain 6
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANLN anillin, actin binding protein
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGAP26 Rho GTPase activating protein 26
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMT1 acidic residue methyltransferase 1
ASB12 ankyrin repeat and SOCS box containing 12
ASB15 ankyrin repeat and SOCS box containing 15
ASCC1 activating signal cointegrator 1 complex subunit 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ASIC5 acid sensing (proton gated) ion channel family member 5
ASRGL1 asparaginase like 1
ATG3 autophagy related 3
ATOX1 antioxidant 1 copper chaperone
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN7L1 ataxin 7-like 1
AVL9 AVL9 homolog (S. cerevisiase)
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BBS7 Bardet-Biedl syndrome 7
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTG4 B-cell translocation gene 4
C10ORF90 chromosome 10 open reading frame 90
C15ORF54 chromosome 15 open reading frame 54
C1ORF100 chromosome 1 open reading frame 100
C1ORF146 chromosome 1 open reading frame 146
C20ORF173 chromosome 20 open reading frame 173
C21ORF62-AS1 C21orf62 antisense RNA 1
C2ORF27B chromosome 2 open reading frame 27B
C2ORF70 chromosome 2 open reading frame 70
C2ORF78 chromosome 2 open reading frame 78
C7ORF69 chromosome 7 open reading frame 69
C8ORF22 chromosome 8 open reading frame 22
C8ORF31 chromosome 8 open reading frame 31
CA8 carbonic anhydrase VIII
CANT1 calcium activated nucleotidase 1
CAPG capping protein (actin filament), gelsolin-like
CAPN14 calpain 14
CARD14 caspase recruitment domain family, member 14
CAT catalase
CCDC152 coiled-coil domain containing 152
CCDC160 coiled-coil domain containing 160
CCDC163P coiled-coil domain containing 163, pseudogene
CCDC172 coiled-coil domain containing 172
CCDC47 coiled-coil domain containing 47
CCDC54 coiled-coil domain containing 54
CCDC70 coiled-coil domain containing 70
CCDC88A coiled-coil domain containing 88A
CCL17 chemokine (C-C motif) ligand 17
CCL22 chemokine (C-C motif) ligand 22
CCNA1 cyclin A1
CCR4 chemokine (C-C motif) receptor 4
CCR8 chemokine (C-C motif) receptor 8
CD70 CD70 molecule
CDC27 cell division cycle 27
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCA2 cell division cycle associated 2
CDHR3 cadherin-related family member 3
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CELF4 CUGBP, Elav-like family member 4
CEP70 centrosomal protein 70kDa
CFHR4 complement factor H-related 4
CFL1P1 cofilin 1 (non-muscle) pseudogene 1
CIT citron rho-interacting serine/threonine kinase
CKLF chemokine-like factor
CLDN12 claudin 12
CLDN14 claudin 14
CLDN20 claudin 20
CLTC clathrin, heavy chain (Hc)
CMC1 C-x(9)-C motif containing 1
CPA2 carboxypeptidase A2 (pancreatic)
CREB3L2 cAMP responsive element binding protein 3-like 2
CRYBB3 crystallin, beta B3
CSAG2 CSAG family, member 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSH2 chorionic somatomammotropin hormone 2
CSRP2 cysteine and glycine-rich protein 2
CST5 cystatin D
CT55 cancer/testis antigen 55
CTXN2 cortexin 2
CXORF40B chromosome X open reading frame 40B
CXORF58 chromosome X open reading frame 58
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAZL deleted in azoospermia-like
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCLRE1A DNA cross-link repair 1A
DEFB131 defensin, beta 131
DEPDC1B DEP domain containing 1B
DEPDC5 DEP domain containing 5
DFNA5 deafness, autosomal dominant 5
DKFZP434J0226 uncharacterized LOC93429
DMC1 DNA meiotic recombinase 1
DNAH11 dynein, axonemal, heavy chain 11
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DRAM1 DNA-damage regulated autophagy modulator 1
DRD3 dopamine receptor D3
DSCR4 Down syndrome critical region 4
DSCR8 Down syndrome critical region 8
DSCR9 Down syndrome critical region 9 (non-protein coding)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DZIP3 DAZ interacting zinc finger protein 3
EDA2R ectodysplasin A2 receptor
EDDM3B epididymal protein 3B
EEA1 early endosome antigen 1
EID1 EP300 interacting inhibitor of differentiation 1
EIF4A3 eukaryotic translation initiation factor 4A3
ELOVL7 ELOVL fatty acid elongase 7
EMILIN2 elastin microfibril interfacer 2
EML5 echinoderm microtubule associated protein like 5
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ENTHD1 ENTH domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPDR1 ependymin related 1
EPHA2 EPH receptor A2
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ETV4 ets variant 4
EZR ezrin
F13B coagulation factor XIII, B polypeptide
FAM102B family with sequence similarity 102, member B
FAM104A family with sequence similarity 104, member A
FAM133B family with sequence similarity 133, member B
FAM169A family with sequence similarity 169, member A
FAM210A family with sequence similarity 210, member A
FCRLA Fc receptor-like A
FDXR ferredoxin reductase
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FLJ37201 tigger transposable element derived 2 pseudogene
FLJ45079 FLJ45079 protein
FMO3 flavin containing monooxygenase 3
FNTB farnesyltransferase, CAAX box, beta
FOXD4L3 forkhead box D4-like 3
FOXP3 forkhead box P3
FXYD2 FXYD domain containing ion transport regulator 2
FYCO1 FYVE and coiled-coil domain containing 1
GAGE1 G antigen 1
GAGE10 G antigen 10
GAGE13 G antigen 13
GAGE2A G antigen 2A
GAGE2B G antigen 2B
GAGE2C G antigen 2C
GAGE2D G antigen 2D
GAGE4 G antigen 4
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHRHR growth hormone releasing hormone receptor
GHSR growth hormone secretagogue receptor
GLRA3 glycine receptor, alpha 3
GLRX glutaredoxin (thioltransferase)
GLYATL1 glycine-N-acyltransferase-like 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GOLT1A golgi transport 1A
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR137C G protein-coupled receptor 137C
GPR19 G protein-coupled receptor 19
GRB10 growth factor receptor-bound protein 10
GSTO2 glutathione S-transferase omega 2
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTSE1 G-2 and S-phase expressed 1
GTSE1-AS1 GTSE1 antisense RNA 1 (head to head)
GUCY2GP guanylate cyclase 2G, pseudogene
HDAC9 histone deacetylase 9
HESX1 HESX homeobox 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HHAT hedgehog acyltransferase
HLTF helicase-like transcription factor
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA4L heat shock 70kDa protein 4-like
IDI1 isopentenyl-diphosphate delta isomerase 1
IKBIP IKBKB interacting protein
IL1R2 interleukin 1 receptor, type II
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INCENP inner centromere protein antigens 135/155kDa
INS-IGF2 INS-IGF2 readthrough
INTS2 integrator complex subunit 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1
KIAA1161 KIAA1161
KIAA1919 KIAA1919
KRT18 keratin 18, type I
LAT linker for activation of T cells
LCLAT1 lysocardiolipin acyltransferase 1
LIMK1 LIM domain kinase 1
LINC00238 long intergenic non-protein coding RNA 238
LINC00242 long intergenic non-protein coding RNA 242
LINC00305 long intergenic non-protein coding RNA 305
LINC00482 long intergenic non-protein coding RNA 482
LINC00520 long intergenic non-protein coding RNA 520
LINC00526 long intergenic non-protein coding RNA 526
LINC00589 long intergenic non-protein coding RNA 589
LMLN leishmanolysin-like (metallopeptidase M8 family)
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LOC100130691 uncharacterized LOC100130691
LOC151174 uncharacterized LOC151174
LOC152225 uncharacterized LOC152225
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRC34 leucine rich repeat containing 34
LRRC59 leucine rich repeat containing 59
LRRC61 leucine rich repeat containing 61
LRRIQ4 leucine-rich repeats and IQ motif containing 4
LSAMP limbic system-associated membrane protein
LSM12 LSM12 homolog (S. cerevisiae)
LSR lipolysis stimulated lipoprotein receptor
LUZP4 leucine zipper protein 4
LY6G6F lymphocyte antigen 6 complex, locus G6F
LY75 lymphocyte antigen 75
MAGEA2 melanoma antigen family A2
MAGEC3 melanoma antigen family C3
MANBA mannosidase, beta A, lysosomal
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK10 mitogen-activated protein kinase 10
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MASTL microtubule associated serine/threonine kinase-like
MAT1A methionine adenosyltransferase I, alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MCAM melanoma cell adhesion molecule
METTL2A methyltransferase like 2A
MFSD11 major facilitator superfamily domain containing 11
MFSD6L major facilitator superfamily domain containing 6-like
MGAT4C MGAT4 family, member C
MGC15885 uncharacterized protein MGC15885
MGC57346 ADP-ribosylation factor pseudogene
MINPP1 multiple inositol-polyphosphate phosphatase 1
MLH1 mutL homolog 1
MLXIP MLX interacting protein
MMP8 matrix metallopeptidase 8
MMS22L MMS22-like, DNA repair protein
MRGPRX2 MAS-related GPR, member X2
MRPS23 mitochondrial ribosomal protein S23
MSI2 musashi RNA-binding protein 2
MTCP1 mature T-cell proliferation 1
MTIF2 mitochondrial translational initiation factor 2
MTMR4 myotubularin related protein 4
NARS asparaginyl-tRNA synthetase
NCEH1 neutral cholesterol ester hydrolase 1
NEK1 NIMA-related kinase 1
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L3 nuclear factor, erythroid 2-like 3
NGB neuroglobin
NKAPP1 NFKB activating protein pseudogene 1
NKX3-1 NK3 homeobox 1
NLRP11 NLR family, pyrin domain containing 11
NPPC natriuretic peptide C
NT5DC1 5'-nucleotidase domain containing 1
NUP50 nucleoporin 50kDa
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2
OR2M1P olfactory receptor, family 2, subfamily M, member 1 pseudogene
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR2T4 olfactory receptor, family 2, subfamily T, member 4
OR4C12 olfactory receptor, family 4, subfamily C, member 12
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR51V1 olfactory receptor, family 51, subfamily V, member 1
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OSBPL10 oxysterol binding protein-like 10
OSBPL3 oxysterol binding protein-like 3
PAGE3 P antigen family, member 3 (prostate associated)
PAGE4 P antigen family, member 4 (prostate associated)
PAGE5 P antigen family, member 5 (prostate associated)
PARK2 parkin RBR E3 ubiquitin protein ligase
PBK PDZ binding kinase
PBLD phenazine biosynthesis-like protein domain containing
PCNA proliferating cell nuclear antigen
PCNXL4 pecanex-like 4 (Drosophila)
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX26 peroxisomal biogenesis factor 26
PHB prohibitin
PHF7 PHD finger protein 7
PHTF2 putative homeodomain transcription factor 2
PIH1D3 PIH1 domain containing 3
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PKDREJ polycystin (PKD) family receptor for egg jelly
PLA1A phospholipase A1 member A
PLA2G10 phospholipase A2, group X
PLA2G2C phospholipase A2, group IIC
PLAC4 placenta-specific 4
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLS1 plastin 1
PLXNB2 plexin B2
PLXNC1 plexin C1
PMCH pro-melanin-concentrating hormone
POC1B POC1 centriolar protein B
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDM7 PR domain containing 7
PRG3 proteoglycan 3
PRR11 proline rich 11
PRR16 proline rich 16
PRR25 proline rich 25
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS37 protease, serine, 37
PRSS55 protease, serine, 55
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PTCHD4 patched domain containing 4
PTPRK protein tyrosine phosphatase, receptor type, K
PTRH2 peptidyl-tRNA hydrolase 2
PWAR5 Prader Willi/Angelman region RNA 5
PWARSN Prader Willi/Angelman region RNA, SNRPN neighbor
RAB15 RAB15, member RAS oncogene family
RAD51B RAD51 paralog B
RALB v-ral simian leukemia viral oncogene homolog B
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM47 RNA binding motif protein 47
RBMXL3 RNA binding motif protein, X-linked-like 3
REPIN1 replication initiator 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNLS renalase, FAD-dependent amine oxidase
RPA1 replication protein A1, 70kDa
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTKN2 rhotekin 2
RTN4IP1 reticulon 4 interacting protein 1
SCARNA18 small Cajal body-specific RNA 18
SCML4 sex comb on midleg-like 4 (Drosophila)
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFXN1 sideroflexin 1
SH3BP1 SH3-domain binding protein 1
SHPK sedoheptulokinase
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKA2 spindle and kinetochore associated complex subunit 2
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC35F6 solute carrier family 35, member F6
SLC39A11 solute carrier family 39, member 11
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMPX small muscle protein, X-linked
SMYD4 SET and MYND domain containing 4
SNRPN small nuclear ribonucleoprotein polypeptide N
SNURF SNRPN upstream reading frame
SOGA3 SOGA family member 3
SPAG9 sperm associated antigen 9
SPATA2 spermatogenesis associated 2
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SQRDL sulfide quinone reductase-like (yeast)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SSX7 synovial sarcoma, X breakpoint 7
SSX8 synovial sarcoma, X breakpoint 8
STEAP2 STEAP family member 2, metalloreductase
STK39 serine threonine kinase 39
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYNJ2BP synaptojanin 2 binding protein
SYT10 synaptotagmin X
SYTL2 synaptotagmin-like 2
TAAR1 trace amine associated receptor 1
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAS2R39 taste receptor, type 2, member 39
TCAM1P testicular cell adhesion molecule 1, pseudogene
TEX13B testis expressed 13B
TEX9 testis expressed 9
TFAM transcription factor A, mitochondrial
TFB1M transcription factor B1, mitochondrial
TMEM161B transmembrane protein 161B
TMEM217 transmembrane protein 217
TMEM38A transmembrane protein 38A
TMIGD1 transmembrane and immunoglobulin domain containing 1
TMPRSS2 transmembrane protease, serine 2
TMPRSS7 transmembrane protease, serine 7
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOM1L1 target of myb1 (chicken)-like 1
TP53TG3B TP53 target 3B
TP53TG5 TP53 target 5
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TPST1 tyrosylprotein sulfotransferase 1
TRABD2A TraB domain containing 2A
TRIM37 tripartite motif containing 37
TRIM61 tripartite motif containing 61
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TTTY7 testis-specific transcript, Y-linked 7 (non-protein coding)
TULP4 tubby like protein 4
TYMSOS TYMS opposite strand
UBASH3B ubiquitin associated and SH3 domain containing B
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UCMA upper zone of growth plate and cartilage matrix associated
UCN2 urocortin 2
URB1-AS1 URB1 antisense RNA 1 (head to head)
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP53 ubiquitin specific peptidase 53
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
VEZF1 vascular endothelial zinc finger 1
VWA5B1 von Willebrand factor A domain containing 5B1
WDR17 WD repeat domain 17
WDR45B WD repeat domain 45B
WDR49 WD repeat domain 49
WDR72 WD repeat domain 72
WDR76 WD repeat domain 76
ZBBX zinc finger, B-box domain containing
ZBED6CL ZBED6 C-terminal like
ZBTB24 zinc finger and BTB domain containing 24
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF114 zinc finger protein 114
ZNF165 zinc finger protein 165
ZNF215 zinc finger protein 215
ZNF280B zinc finger protein 280B
ZNF460 zinc finger protein 460
ZNF689 zinc finger protein 689
ZNF778 zinc finger protein 778
ZNF789 zinc finger protein 789
ZSCAN5A zinc finger and SCAN domain containing 5A

low expression

Symbol Name
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
SET SET nuclear proto-oncogene