Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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295 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTA2 actin, alpha 2, smooth muscle, aorta
ACVRL1 activin A receptor type II-like 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
AHRR aryl-hydrocarbon receptor repressor
AHSP alpha hemoglobin stabilizing protein
AOC3 amine oxidase, copper containing 3
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOL5 apolipoprotein L, 5
AQP12A aquaporin 12A
AQP12B aquaporin 12B
AQP7 aquaporin 7
ARHGAP23 Rho GTPase activating protein 23
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATRN attractin
AZU1 azurocidin 1
C14ORF180 chromosome 14 open reading frame 180
C15ORF56 chromosome 15 open reading frame 56
C20ORF194 chromosome 20 open reading frame 194
C20ORF202 chromosome 20 open reading frame 202
C2ORF50 chromosome 2 open reading frame 50
C6 complement component 6
C7 complement component 7
CA1 carbonic anhydrase I
CA8 carbonic anhydrase VIII
CABLES2 Cdk5 and Abl enzyme substrate 2
CCM2L cerebral cavernous malformation 2-like
CCNDBP1 cyclin D-type binding-protein 1
CD300LG CD300 molecule-like family member g
CD34 CD34 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP250 centrosomal protein 250kDa
CEP68 centrosomal protein 68kDa
CHD6 chromodomain helicase DNA binding protein 6
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CLASP1 cytoplasmic linker associated protein 1
CLEC14A C-type lectin domain family 14, member A
CLEC3B C-type lectin domain family 3, member B
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNN1 calponin 1, basic, smooth muscle
COMMD7 COMM domain containing 7
CPNE2 copine II
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRAMP1L Crm, cramped-like (Drosophila)
CRNKL1 crooked neck pre-mRNA splicing factor 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CSRP2BP CSRP2 binding protein
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CXORF36 chromosome X open reading frame 36
CYFIP1 cytoplasmic FMR1 interacting protein 1
DAPK1 death-associated protein kinase 1
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCAF8 DDB1 and CUL4 associated factor 8
DEFA1B defensin, alpha 1B
DEFA4 defensin, alpha 4, corticostatin
DEFB132 defensin, beta 132
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DKFZP434H168 uncharacterized LOC26077
DOPEY2 dopey family member 2
DPT dermatopontin
DSCR3 Down syndrome critical region 3
DSTN destrin (actin depolymerizing factor)
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDN1 endothelin 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELANE elastase, neutrophil expressed
ELMO2 engulfment and cell motility 2
ELN elastin
EPB42 erythrocyte membrane protein band 4.2
ESPNL espin-like
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FAM110D family with sequence similarity 110, member D
FAM205BP transmembrane protein C9orf144B pseudogene
FAM213B family with sequence similarity 213, member B
FAM219B family with sequence similarity 219, member B
FAM53B family with sequence similarity 53, member B
FAM65A family with sequence similarity 65, member A
FASTKD5 FAST kinase domains 5
FGD5 FYVE, RhoGEF and PH domain containing 5
FN1 fibronectin 1
FOXD4L3 forkhead box D4-like 3
FOXD4L6 forkhead box D4-like 6
FOXS1 forkhead box S1
FUCA1 fucosidase, alpha-L- 1, tissue
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GATA1 GATA binding protein 1 (globin transcription factor 1)
GGT5 gamma-glutamyltransferase 5
GID8 GID complex subunit 8
GJD3 gap junction protein, delta 3, 31.9kDa
GLP2R glucagon-like peptide 2 receptor
GLYAT glycine-N-acyltransferase
GPR157 G protein-coupled receptor 157
GYPB glycophorin B (MNS blood group)
GZF1 GDNF-inducible zinc finger protein 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HBD hemoglobin, delta
HBM hemoglobin, mu
HCAR1 hydroxycarboxylic acid receptor 1
HCG9 HLA complex group 9 (non-protein coding)
HIST2H3D histone cluster 2, H3d
HIST2H4A histone cluster 2, H4a
HIST3H2A histone cluster 3, H2a
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFT52 intraflagellar transport 52
IL6R interleukin 6 receptor
INMT indolethylamine N-methyltransferase
INSC inscuteable homolog (Drosophila)
ITGAD integrin, alpha D
ITPKB inositol-trisphosphate 3-kinase B
ITSN1 intersectin 1 (SH3 domain protein)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KIAA1462 KIAA1462
KIAA1614 KIAA1614
KIF3B kinesin family member 3B
KIRREL kin of IRRE like (Drosophila)
KLB klotho beta
KLF13 Kruppel-like factor 13
KLHL33 kelch-like family member 33
KRTAP19-8 keratin associated protein 19-8
LAMA5 laminin, alpha 5
LMOD1 leiomodin 1 (smooth muscle)
LOC388242 coiled-coil domain containing 101 pseudogene
LRRC3 leucine rich repeat containing 3
LRRC43 leucine rich repeat containing 43
LRRK1 leucine-rich repeat kinase 1
LY6G6F lymphocyte antigen 6 complex, locus G6F
MAGEL2 melanoma antigen family L2
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MAVS mitochondrial antiviral signaling protein
MCM3AP minichromosome maintenance complex component 3 associated protein
MFAP4 microfibrillar-associated protein 4
MKL2 MKL/myocardin-like 2
MME membrane metallo-endopeptidase
MMP23B matrix metallopeptidase 23B
MMRN1 multimerin 1
MOCS3 molybdenum cofactor synthesis 3
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MPO myeloperoxidase
MRGPRF MAS-related GPR, member F
MRVI1 murine retrovirus integration site 1 homolog
MUSTN1 musculoskeletal, embryonic nuclear protein 1
MX1 MX dynamin-like GTPase 1
MYCT1 myc target 1
MYH11 myosin, heavy chain 11, smooth muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYL9 myosin, light chain 9, regulatory
MYOCD myocardin
MYOZ1 myozenin 1
N4BP1 NEDD4 binding protein 1
N4BP3 NEDD4 binding protein 3
NCK2 NCK adaptor protein 2
NCOA4 nuclear receptor coactivator 4
NCOA6 nuclear receptor coactivator 6
NDN necdin, melanoma antigen (MAGE) family member
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NOL4L nucleolar protein 4-like
NPFFR1 neuropeptide FF receptor 1
NRIP2 nuclear receptor interacting protein 2
OLFML1 olfactomedin-like 1
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OR9K2 olfactory receptor, family 9, subfamily K, member 2
PANK2 pantothenate kinase 2
PARD3B par-3 family cell polarity regulator beta
PARP6 poly (ADP-ribose) polymerase family, member 6
PBLD phenazine biosynthesis-like protein domain containing
PCDH1 protocadherin 1
PCDHGB6 protocadherin gamma subfamily B, 6
PCNT pericentrin
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PEAR1 platelet endothelial aggregation receptor 1
PF4 platelet factor 4
PGF placental growth factor
PGM5 phosphoglucomutase 5
PHF20 PHD finger protein 20
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLAGL2 pleiomorphic adenoma gene-like 2
PLCB2 phospholipase C, beta 2
PLCG1 phospholipase C, gamma 1
PLCL2 phospholipase C-like 2
PLIN1 perilipin 1
PLXNA1 plexin A1
PLXND1 plexin D1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRTG protogenin
PRTN3 proteinase 3
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTCH2 patched 2
PTPRA protein tyrosine phosphatase, receptor type, A
PYGB phosphorylase, glycogen; brain
PYGM phosphorylase, glycogen, muscle
RAI2 retinoic acid induced 2
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBBP9 retinoblastoma binding protein 9
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBM38 RNA binding motif protein 38
RFTN1 raftlin, lipid raft linker 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIPK4 receptor-interacting serine-threonine kinase 4
RNF24 ring finger protein 24
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RRP1B ribosomal RNA processing 1B
SAMHD1 SAM domain and HD domain 1
SCAMP5 secretory carrier membrane protein 5
SCN4A sodium channel, voltage gated, type IV alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHE Src homology 2 domain containing E
SIAH1 siah E3 ubiquitin protein ligase 1
SIRPB1 signal-regulatory protein beta 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLIT3 slit homolog 3 (Drosophila)
SMAD6 SMAD family member 6
SMOC2 SPARC related modular calcium binding 2
SNN stannin
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNPH syntaphilin
SNTA1 syntrophin, alpha 1
SNX5 sorting nexin 5
SOGA1 suppressor of glucose, autophagy associated 1
SOX12 SRY (sex determining region Y)-box 12
SOX18 SRY (sex determining region Y)-box 18
SRL sarcalumenin
STAB2 stabilin 2
STK35 serine/threonine kinase 35
SUSD1 sushi domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYS1 Sys1 golgi trafficking protein
TADA2B transcriptional adaptor 2B
TAGLN transgelin
TBC1D20 TBC1 domain family, member 20
TBC1D2B TBC1 domain family, member 2B
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TJP1 tight junction protein 1
TLR5 toll-like receptor 5
TMEM119 transmembrane protein 119
TMEM132C transmembrane protein 132C
TMEM240 transmembrane protein 240
TMPRSS2 transmembrane protease, serine 2
TRAPPC10 trafficking protein particle complex 10
TRIM8 tripartite motif containing 8
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTPAL tocopherol (alpha) transfer protein-like
TTTY5 testis-specific transcript, Y-linked 5 (non-protein coding)
TYRO3 TYRO3 protein tyrosine kinase
USHBP1 Usher syndrome 1C binding protein 1
VWF von Willebrand factor
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBTB42 zinc finger and BTB domain containing 42
ZCCHC3 zinc finger, CCHC domain containing 3
ZFP64 ZFP64 zinc finger protein
ZNF343 zinc finger protein 343
ZNF366 zinc finger protein 366
ZNF496 zinc finger protein 496
ZNF552 zinc finger protein 552
ZNF592 zinc finger protein 592
ZNF710 zinc finger protein 710
ZNFX1 zinc finger, NFX1-type containing 1
ZSWIM3 zinc finger, SWIM-type containing 3
ZYG11A zyg-11 family member A, cell cycle regulator