Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MN-06A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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283 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MN-06A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACBD3 acyl-CoA binding domain containing 3
ACO2 aconitase 2, mitochondrial
ACSL5 acyl-CoA synthetase long-chain family member 5
ADSS adenylosuccinate synthase
AFF3 AF4/FMR2 family, member 3
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMOTL2 angiomotin like 2
ANGEL2 angel homolog 2 (Drosophila)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD34B ankyrin repeat domain 34B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
APOL4 apolipoprotein L, 4
ARID1B AT rich interactive domain 1B (SWI1-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATE1 arginyltransferase 1
ATF4 activating transcription factor 4
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVL9 AVL9 homolog (S. cerevisiase)
BAIAP2L2 BAI1-associated protein 2-like 2
BCAS3 breast carcinoma amplified sequence 3
BCYRN1 brain cytoplasmic RNA 1
BPTF bromodomain PHD finger transcription factor
C1ORF100 chromosome 1 open reading frame 100
C1QTNF6 C1q and tumor necrosis factor related protein 6
C8ORF37 chromosome 8 open reading frame 37
CA5B carbonic anhydrase VB, mitochondrial
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBX4 chromobox homolog 4
CBX6 chromobox homolog 6
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC47 coiled-coil domain containing 47
CCNI cyclin I
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDK12 cyclin-dependent kinase 12
CFAP126 cilia and flagella associated protein 126
COG2 component of oligomeric golgi complex 2
COX19 COX19 cytochrome c oxidase assembly factor
CPSF4L cleavage and polyadenylation specific factor 4-like
CRTAC1 cartilage acidic protein 1
CRYGA crystallin, gamma A
CSRP2 cysteine and glycine-rich protein 2
CTIF CBP80/20-dependent translation initiation factor
CTSL cathepsin L
CYCSP52 cytochrome c, somatic pseudogene 52
DDR2 discoidin domain receptor tyrosine kinase 2
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DENND1A DENN/MADD domain containing 1A
DEPDC5 DEP domain containing 5
DESI1 desumoylating isopeptidase 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIEXF digestive organ expansion factor homolog (zebrafish)
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DMXL1 Dmx-like 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAL4 dynein, axonemal, light chain 4
DRD3 dopamine receptor D3
DRG1 developmentally regulated GTP binding protein 1
EDDM3B epididymal protein 3B
EFHB EF-hand domain family, member B
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EP300 E1A binding protein p300
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM126A family with sequence similarity 126, member A
FAM129A family with sequence similarity 129, member A
FAM160B1 family with sequence similarity 160, member B1
FAM20B family with sequence similarity 20, member B
FAM219B family with sequence similarity 219, member B
FAM53B family with sequence similarity 53, member B
FBXO28 F-box protein 28
FBXO7 F-box protein 7
FEM1B fem-1 homolog b (C. elegans)
FMNL2 formin-like 2
FOXF2 forkhead box F2
FOXK1 forkhead box K1
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GARS glycyl-tRNA synthetase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLI2 GLI family zinc finger 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPNMB glycoprotein (transmembrane) nmb
GPR137B G protein-coupled receptor 137B
GPRC5B G protein-coupled receptor, class C, group 5, member B
GTPBP1 GTP binding protein 1
HCG11 HLA complex group 11 (non-protein coding)
HELZ helicase with zinc finger
HIPK2 homeodomain interacting protein kinase 2
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-H major histocompatibility complex, class I, H (pseudogene)
HOXA11 homeobox A11
HOXA4 homeobox A4
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
IDI2-AS1 IDI2 antisense RNA 1
IFNA5 interferon, alpha 5
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IL5 interleukin 5
IQCK IQ motif containing K
IQGAP2 IQ motif containing GTPase activating protein 2
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRS2 insulin receptor substrate 2
IVNS1ABP influenza virus NS1A binding protein
JOSD1 Josephin domain containing 1
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KIF25 kinesin family member 25
KLF11 Kruppel-like factor 11
KLF15 Kruppel-like factor 15
KLHL21 kelch-like family member 21
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LATS1 large tumor suppressor kinase 1
LGALS9B lectin, galactoside-binding, soluble, 9B
LGTN ligatin
LOC115110 uncharacterized LOC115110
LOC285593 uncharacterized LOC285593
LOC340357 uncharacterized LOC340357
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAG myelin associated glycoprotein
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MED1 mediator complex subunit 1
MFAP3L microfibrillar-associated protein 3-like
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIEF1 mitochondrial elongation factor 1
MINK1 misshapen-like kinase 1
MSGN1 mesogenin 1
MSI2 musashi RNA-binding protein 2
MTSS1L metastasis suppressor 1-like
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
MYCNOS MYCN opposite strand
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NATD1 N-acetyltransferase domain containing 1
NHEJ1 nonhomologous end-joining factor 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPTXR neuronal pentraxin receptor
ODF3L1 outer dense fiber of sperm tails 3-like 1
OR10G2 olfactory receptor, family 10, subfamily G, member 2
OR10W1 olfactory receptor, family 10, subfamily W, member 1
OR11L1 olfactory receptor, family 11, subfamily L, member 1
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR5B12 olfactory receptor, family 5, subfamily B, member 12
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCDHGA10 protocadherin gamma subfamily A, 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PER2 period circadian clock 2
PER3 period circadian clock 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PICK1 protein interacting with PRKCA 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PISD phosphatidylserine decarboxylase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLP1 proteolipid protein 1
PLXNC1 plexin C1
POLH polymerase (DNA directed), eta
POM121L2 POM121 transmembrane nucleoporin-like 2
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPBPP2 pro-platelet basic protein pseudogene 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRR14L proline rich 14-like
PRRC2B proline-rich coiled-coil 2B
PRRC2C proline-rich coiled-coil 2C
PTCH1 patched 1
PTEN phosphatase and tensin homolog
R3HCC1L R3H domain and coiled-coil containing 1-like
RBM20 RNA binding motif protein 20
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF38 ring finger protein 38
RPL4 ribosomal protein L4
RPS10P7 ribosomal protein S10 pseudogene 7
RRAGD Ras-related GTP binding D
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SAP30BP SAP30 binding protein
SASH1 SAM and SH3 domain containing 1
SCARNA8 small Cajal body-specific RNA 8
SCYL3 SCY1-like 3 (S. cerevisiae)
SEC63 SEC63 homolog (S. cerevisiae)
SEPT3 septin 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFT2D3 SFT2 domain containing 3
SH3BP4 SH3-domain binding protein 4
SHPK sedoheptulokinase
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC39A11 solute carrier family 39, member 11
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11
SMG7 SMG7 nonsense mediated mRNA decay factor
SNORA4 small nucleolar RNA, H/ACA box 4
SNX25 sorting nexin 25
SOCS7 suppressor of cytokine signaling 7
SPAG9 sperm associated antigen 9
SPATA13 spermatogenesis associated 13
SPATS1 spermatogenesis associated, serine-rich 1
SPIRE1 spire-type actin nucleation factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRP68 signal recognition particle 68kDa
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST20-AS1 ST20 antisense RNA 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAT5A signal transducer and activator of transcription 5A
STK24 serine/threonine kinase 24
STK32A serine/threonine kinase 32A
STRADA STE20-related kinase adaptor alpha
STX6 syntaxin 6
SUN1 Sad1 and UNC84 domain containing 1
SUSD5 sushi domain containing 5
SYN3 synapsin III
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TACR2 tachykinin receptor 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBATA thymus, brain and testes associated
TBC1D16 TBC1 domain family, member 16
TCF20 transcription factor 20 (AR1)
TEF thyrotrophic embryonic factor
THRAP3 thyroid hormone receptor associated protein 3
TLR1 toll-like receptor 1
TMEM11 transmembrane protein 11
TMEM52B transmembrane protein 52B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNRC6C trinucleotide repeat containing 6C
TNS3 tensin 3
TOB2 transducer of ERBB2, 2
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast)
TPCN1 two pore segment channel 1
TRH thyrotropin-releasing hormone
TRIM4 tripartite motif containing 4
TRIM47 tripartite motif containing 47
TRIOBP TRIO and F-actin binding protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TULP4 tubby like protein 4
TXN2 thioredoxin 2
ULK4 unc-51 like kinase 4
UNK unkempt family zinc finger
USP22 ubiquitin specific peptidase 22
USP42 ubiquitin specific peptidase 42
USP54 ubiquitin specific peptidase 54
VAV3 vav 3 guanine nucleotide exchange factor
WDR31 WD repeat domain 31
WDR37 WD repeat domain 37
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB47 zinc finger and BTB domain containing 47
ZC3H11A zinc finger CCCH-type containing 11A
ZC3H7B zinc finger CCCH-type containing 7B
ZIC4 Zic family member 4
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF438 zinc finger protein 438
ZNF672 zinc finger protein 672
ZSCAN21 zinc finger and SCAN domain containing 21
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

low expression

Symbol Name
ECI2 enoyl-CoA delta isomerase 2
PXMP4 peroxisomal membrane protein 4, 24kDa
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
TRIM68 tripartite motif containing 68
UBB ubiquitin B