Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AF-06A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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221 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AF-06A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACAT1 acetyl-CoA acetyltransferase 1
ACOT1 acyl-CoA thioesterase 1
ACOT2 acyl-CoA thioesterase 2
AEN apoptosis enhancing nuclease
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AKAP4 A kinase (PRKA) anchor protein 4
ALG9 ALG9, alpha-1,2-mannosyltransferase
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
AMDHD2 amidohydrolase domain containing 2
AMPH amphiphysin
ANGEL1 angel homolog 1 (Drosophila)
ANO8 anoctamin 8
ANXA4 annexin A4
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APEH acylaminoacyl-peptide hydrolase
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARPIN actin-related protein 2/3 complex inhibitor
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ARSD arylsulfatase D
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ASL argininosuccinate lyase
ATF6B activating transcription factor 6 beta
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BPHL biphenyl hydrolase-like (serine hydrolase)
BTBD9 BTB (POZ) domain containing 9
C16ORF62 chromosome 16 open reading frame 62
C19ORF25 chromosome 19 open reading frame 25
C19ORF40 chromosome 19 open reading frame 40
C19ORF71 chromosome 19 open reading frame 71
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF31 chromosome 7 open reading frame 31
C9ORF24 chromosome 9 open reading frame 24
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CARD16 caspase recruitment domain family, member 16
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CATSPER4 cation channel, sperm associated 4
CCDC163P coiled-coil domain containing 163, pseudogene
CD99L2 CD99 molecule-like 2
CDC16 cell division cycle 16
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP41 centrosomal protein 41kDa
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CIT citron rho-interacting serine/threonine kinase
CLYBL citrate lyase beta like
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CREB3L2 cAMP responsive element binding protein 3-like 2
CRTC3 CREB regulated transcription coactivator 3
CUL7 cullin 7
DALRD3 DALR anticodon binding domain containing 3
DCAF11 DDB1 and CUL4 associated factor 11
DCPS decapping enzyme, scavenger
DDB2 damage-specific DNA binding protein 2, 48kDa
DET1 de-etiolated homolog 1 (Arabidopsis)
DFNA5 deafness, autosomal dominant 5
DNAAF3 dynein, axonemal, assembly factor 3
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
DUSP10 dual specificity phosphatase 10
DVL2 dishevelled segment polarity protein 2
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EI24 etoposide induced 2.4
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ESD esterase D
ETHE1 ethylmalonic encephalopathy 1
EXD2 exonuclease 3'-5' domain containing 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM149A family with sequence similarity 149, member A
FAM185A family with sequence similarity 185, member A
FAM201A family with sequence similarity 201, member A
FAM86B2 family with sequence similarity 86, member B2
FOXR1 forkhead box R1
GADL1 glutamate decarboxylase-like 1
GALM galactose mutarotase (aldose 1-epimerase)
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GCDH glutaryl-CoA dehydrogenase
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNPDA1 glucosamine-6-phosphate deaminase 1
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
HADH hydroxyacyl-CoA dehydrogenase
HDDC3 HD domain containing 3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HELT helt bHLH transcription factor
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHLA2 HERV-H LTR-associating 2
HIST1H4L histone cluster 1, H4l
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
HSPB2 heat shock 27kDa protein 2
HYKK hydroxylysine kinase
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IPO5 importin 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0100 KIAA0100
KIAA0141 KIAA0141
KIAA0391 KIAA0391
KIAA1549L KIAA1549-like
KLRC3 killer cell lectin-like receptor subfamily C, member 3
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LHFPL4 lipoma HMGIC fusion partner-like 4
LINC00323 long intergenic non-protein coding RNA 323
LOC644936 actin, beta pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC16A leucine rich repeat containing 16A
LSAMP limbic system-associated membrane protein
LY6G5C lymphocyte antigen 6 complex, locus G5C
MALSU1 mitochondrial assembly of ribosomal large subunit 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MCF2 MCF.2 cell line derived transforming sequence
MCTS1 malignant T cell amplified sequence 1
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MFSD12 major facilitator superfamily domain containing 12
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MIPEP mitochondrial intermediate peptidase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS11 mitochondrial ribosomal protein S11
MYO1D myosin ID
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NICN1 nicolin 1
NOP9 NOP9 nucleolar protein
NOX3 NADPH oxidase 3
NRL neural retina leucine zipper
NT5M 5',3'-nucleotidase, mitochondrial
NUDCD3 NudC domain containing 3
OIT3 oncoprotein induced transcript 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR10K1 olfactory receptor, family 10, subfamily K, member 1
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR6K6 olfactory receptor, family 6, subfamily K, member 6
OR8A1 olfactory receptor, family 8, subfamily A, member 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PARP4 poly (ADP-ribose) polymerase family, member 4
PCDHA10 protocadherin alpha 10
PCDHA13 protocadherin alpha 13
PCDHB8 protocadherin beta 8
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGB2 protocadherin gamma subfamily B, 2
PEX11A peroxisomal biogenesis factor 11 alpha
PHYH phytanoyl-CoA 2-hydroxylase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLD1 phospholipase D1, phosphatidylcholine-specific
PNPO pyridoxamine 5'-phosphate oxidase
POLG polymerase (DNA directed), gamma
POMZP3 POM121 and ZP3 fusion
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPT2 palmitoyl-protein thioesterase 2
PTPRH protein tyrosine phosphatase, receptor type, H
PYGL phosphorylase, glycogen, liver
RAD51D RAD51 paralog D
RENBP renin binding protein
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RMI2 RecQ mediated genome instability 2
RNF182 ring finger protein 182
RTN2 reticulon 2
RTP2 receptor (chemosensory) transporter protein 2
SCML4 sex comb on midleg-like 4 (Drosophila)
SCO1 SCO1 cytochrome c oxidase assembly protein
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SKA3 spindle and kinetochore associated complex subunit 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17
SMC1A structural maintenance of chromosomes 1A
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
SRI sorcin
SRR serine racemase
STAT5A signal transducer and activator of transcription 5A
STOML1 stomatin (EPB72)-like 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYT5 synaptotagmin V
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
TBX6 T-box 6
TDRD3 tudor domain containing 3
TECPR1 tectonin beta-propeller repeat containing 1
TECPR2 tectonin beta-propeller repeat containing 2
TFRC transferrin receptor
TM9SF1 transmembrane 9 superfamily member 1
TMEM145 transmembrane protein 145
TMEM164 transmembrane protein 164
TMEM63A transmembrane protein 63A
TMEM86A transmembrane protein 86A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNNI3 troponin I type 3 (cardiac)
TSSK6 testis-specific serine kinase 6
TYR tyrosinase
UBAC2 UBA domain containing 2
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UHRF1BP1 UHRF1 binding protein 1
ULK3 unc-51 like kinase 3
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VARS2 valyl-tRNA synthetase 2, mitochondrial
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
ZBED3 zinc finger, BED-type containing 3
ZDHHC4 zinc finger, DHHC-type containing 4
ZNF689 zinc finger protein 689
ZNF837 zinc finger protein 837

low expression

Symbol Name
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
SETD6 SET domain containing 6
WDR33 WD repeat domain 33