Skin Cutaneous Melanoma_SKCM_TCGA-ER-A193-06A-12R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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330 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-ER-A193-06A-12R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD17C abhydrolase domain containing 17C
ABHD2 abhydrolase domain containing 2
ABLIM2 actin binding LIM protein family, member 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL6 acyl-CoA synthetase long-chain family member 6
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIRF adipogenesis regulatory factor
AGBL3 ATP/GTP binding protein-like 3
AGBL5 ATP/GTP binding protein-like 5
AGO4 argonaute RISC catalytic component 4
AK3 adenylate kinase 3
AK5 adenylate kinase 5
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
ANGEL1 angel homolog 1 (Drosophila)
ANKRD28 ankyrin repeat domain 28
ANKRD29 ankyrin repeat domain 29
ANKRD6 ankyrin repeat domain 6
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANXA3 annexin A3
AOC3 amine oxidase, copper containing 3
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AQP7 aquaporin 7
ARHGAP9 Rho GTPase activating protein 9
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARL17B ADP-ribosylation factor-like 17B
ARMC9 armadillo repeat containing 9
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARPIN actin-related protein 2/3 complex inhibitor
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2A1 BCL2-related protein A1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BEND7 BEN domain containing 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BOC BOC cell adhesion associated, oncogene regulated
BSX brain-specific homeobox
C14ORF180 chromosome 14 open reading frame 180
C15ORF26 chromosome 15 open reading frame 26
C15ORF61 chromosome 15 open reading frame 61
C1ORF146 chromosome 1 open reading frame 146
C2ORF57 chromosome 2 open reading frame 57
C2ORF69 chromosome 2 open reading frame 69
C4ORF36 chromosome 4 open reading frame 36
C6 complement component 6
C7ORF49 chromosome 7 open reading frame 49
CADPS2 Ca++-dependent secretion activator 2
CAND1 cullin-associated and neddylation-dissociated 1
CCDC141 coiled-coil domain containing 141
CCDC3 coiled-coil domain containing 3
CCDC85C coiled-coil domain containing 85C
CDC37L1 cell division cycle 37-like 1
CDK17 cyclin-dependent kinase 17
CEMIP cell migration inducing protein, hyaluronan binding
CEP170B centrosomal protein 170B
CFD complement factor D (adipsin)
CGNL1 cingulin-like 1
CIDEC cell death-inducing DFFA-like effector c
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNRIP1 cannabinoid receptor interacting protein 1
COX5A cytochrome c oxidase subunit Va
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPM carboxypeptidase M
CPXM2 carboxypeptidase X (M14 family), member 2
CRTC3 CREB regulated transcription coactivator 3
CUX1 cut-like homeobox 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DCHS2 dachsous cadherin-related 2
DENND4A DENN/MADD domain containing 4A
DFNA5 deafness, autosomal dominant 5
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIRC3 disrupted in renal carcinoma 3
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DMTN dematin actin binding protein
DPP8 dipeptidyl-peptidase 8
DTNB dystrobrevin, beta
DUSP7 dual specificity phosphatase 7
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EBF4 early B-cell factor 4
EDN1 endothelin 1
EFR3B EFR3 homolog B (S. cerevisiae)
EFTUD1 elongation factor Tu GTP binding domain containing 1
EIF5 eukaryotic translation initiation factor 5
EML5 echinoderm microtubule associated protein like 5
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB1 EPH receptor B1
ESYT2 extended synaptotagmin-like protein 2
EVA1C eva-1 homolog C (C. elegans)
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FAM219B family with sequence similarity 219, member B
FBXO41 F-box protein 41
FBXO44 F-box protein 44
FGF1 fibroblast growth factor 1 (acidic)
FGFBP2 fibroblast growth factor binding protein 2
FHL5 four and a half LIM domains 5
FLJ34503 uncharacterized FLJ34503
FNDC4 fibronectin type III domain containing 4
FOXA1 forkhead box A1
GALP galanin-like peptide
GJA10 gap junction protein, alpha 10, 62kDa
GLCE glucuronic acid epimerase
GLYAT glycine-N-acyltransferase
GOLGA3 golgin A3
GOLGA6L10 golgin A6 family-like 10
GOLGA6L9 golgin A6 family-like 9
GPR45 G protein-coupled receptor 45
GRK1 G protein-coupled receptor kinase 1
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HAR1A highly accelerated region 1A (non-protein coding)
HCG4B HLA complex group 4B (non-protein coding)
HIST1H3F histone cluster 1, H3f
HLX H2.0-like homeobox
HOMER2 homer scaffolding protein 2
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HYKK hydroxylysine kinase
IDO1 indoleamine 2,3-dioxygenase 1
IFRD1 interferon-related developmental regulator 1
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IL12RB2 interleukin 12 receptor, beta 2
IL9R interleukin 9 receptor
INGX inhibitor of growth family, X-linked, pseudogene
IQCH IQ motif containing H
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRX1 iroquois homeobox 1
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KANK2 KN motif and ankyrin repeat domains 2
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCNIP2 Kv channel interacting protein 2
KIAA0754 KIAA0754
KIF23 kinesin family member 23
KIF7 kinesin family member 7
KLB klotho beta
KLHL25 kelch-like family member 25
KLHL3 kelch-like family member 3
LARP6 La ribonucleoprotein domain family, member 6
LBX1 ladybird homeobox 1
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LHFPL4 lipoma HMGIC fusion partner-like 4
LINC00028 long intergenic non-protein coding RNA 28
LINC00159 long intergenic non-protein coding RNA 159
LINC00173 long intergenic non-protein coding RNA 173
LINC00341 long intergenic non-protein coding RNA 341
LIPE lipase, hormone-sensitive
LOC100126784 uncharacterized LOC100126784
LOC100130238 uncharacterized LOC100130238
LOC283731 uncharacterized LOC283731
LPIN3 lipin 3
LRP11 low density lipoprotein receptor-related protein 11
LRRC75A leucine rich repeat containing 75A
LRRK1 leucine-rich repeat kinase 1
LTA4H leukotriene A4 hydrolase
MACF1 microtubule-actin crosslinking factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K5 mitogen-activated protein kinase kinase 5
MDM1 Mdm1 nuclear protein homolog (mouse)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEGF6 multiple EGF-like-domains 6
MESDC1 mesoderm development candidate 1
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MID2 midline 2
MMP13 matrix metallopeptidase 13
MRAS muscle RAS oncogene homolog
MSLN mesothelin
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH11 myosin, heavy chain 11, smooth muscle
MYO5B myosin VB
MYO9A myosin IXA
MYOCD myocardin
MYOM1 myomesin 1
NBPF3 neuroblastoma breakpoint family, member 3
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NGRN neugrin, neurite outgrowth associated
NMT2 N-myristoyltransferase 2
NNMT nicotinamide N-methyltransferase
NOX4 NADPH oxidase 4
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRCAM neuronal cell adhesion molecule
NRROS negative regulator of reactive oxygen species
NT5E 5'-nucleotidase, ecto (CD73)
NUAK1 NUAK family, SNF1-like kinase, 1
NUP107 nucleoporin 107kDa
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR4D6 olfactory receptor, family 4, subfamily D, member 6
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR7A5 olfactory receptor, family 7, subfamily A, member 5
PALD1 phosphatase domain containing, paladin 1
PARD3B par-3 family cell polarity regulator beta
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP16 poly (ADP-ribose) polymerase family, member 16
PARP6 poly (ADP-ribose) polymerase family, member 6
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PBX4 pre-B-cell leukemia homeobox 4
PCDHA10 protocadherin alpha 10
PCDHA13 protocadherin alpha 13
PCDHGB2 protocadherin gamma subfamily B, 2
PDE8A phosphodiesterase 8A
PEX11A peroxisomal biogenesis factor 11 alpha
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PGPEP1 pyroglutamyl-peptidase I
PHF20 PHD finger protein 20
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PIAS1 protein inhibitor of activated STAT, 1
PKP4 plakophilin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCG1 phospholipase C, gamma 1
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLIN1 perilipin 1
PLIN4 perilipin 4
PNPLA2 patatin-like phospholipase domain containing 2
POLG polymerase (DNA directed), gamma
PPARA peroxisome proliferator-activated receptor alpha
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R36 protein phosphatase 1, regulatory subunit 36
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT8 protein arginine methyltransferase 8
PRPH2 peripherin 2 (retinal degeneration, slow)
PTPRG protein tyrosine phosphatase, receptor type, G
RAP1B RAP1B, member of RAS oncogene family
RASEF RAS and EF-hand domain containing
RBP2 retinol binding protein 2, cellular
RBP4 retinol binding protein 4, plasma
RCCD1 RCC1 domain containing 1
RIN3 Ras and Rab interactor 3
RLN1 relaxin 1
RLN2 relaxin 2
RNASE4 ribonuclease, RNase A family, 4
RNF180 ring finger protein 180
RPL23AP64 ribosomal protein L23a pseudogene 64
RPLP1 ribosomal protein, large, P1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPSAP52 ribosomal protein SA pseudogene 52
SCAPER S-phase cyclin A-associated protein in the ER
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SEPT4 septin 4
SEPT7P9 septin 7 pseudogene 9
SERAC1 serine active site containing 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
SIMC1 SUMO-interacting motifs containing 1
SKOR1 SKI family transcriptional corepressor 1
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC35E2 solute carrier family 35, member E2
SLC35E3 solute carrier family 35, member E3
SLC35F5 solute carrier family 35, member F5
SMAD3 SMAD family member 3
SMN1 survival of motor neuron 1, telomeric
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA45A small nucleolar RNA, H/ACA box 45A
SNRPF small nuclear ribonucleoprotein polypeptide F
SOGA1 suppressor of glucose, autophagy associated 1
SPARCL1 SPARC-like 1 (hevin)
SPEF1 sperm flagellar 1
SSPN sarcospan
SSX4 synovial sarcoma, X breakpoint 4
SSX5 synovial sarcoma, X breakpoint 5
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene)
ST20 suppressor of tumorigenicity 20
ST20-AS1 ST20 antisense RNA 1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STK32A serine/threonine kinase 32A
STK39 serine threonine kinase 39
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SUMO3 small ubiquitin-like modifier 3
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYNJ2 synaptojanin 2
SYNPO2 synaptopodin 2
TACR1 tachykinin receptor 1
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TARSL2 threonyl-tRNA synthetase-like 2
TBC1D2B TBC1 domain family, member 2B
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX18 T-box 18
TCF23 transcription factor 23
TESK2 testis-specific kinase 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THAP10 THAP domain containing 10
THBS2 thrombospondin 2
TLE3 transducin-like enhancer of split 3
TMEM132C transmembrane protein 132C
TMEM140 transmembrane protein 140
TNS1 tensin 1
TNXB tenascin XB
TRIM56 tripartite motif containing 56
TTC3 tetratricopeptide repeat domain 3
TTC7B tetratricopeptide repeat domain 7B
TTN titin
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding)
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TUSC5 tumor suppressor candidate 5
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2Q2P1 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1
UCN3 urocortin 3
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
XIRP1 xin actin binding repeat containing 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFR2 zinc finger RNA binding protein 2
ZHX3 zinc fingers and homeoboxes 3
ZNF592 zinc finger protein 592
ZNF683 zinc finger protein 683
ZNF710 zinc finger protein 710

low expression

Symbol Name
SETD6 SET domain containing 6
ZNF786 zinc finger protein 786