Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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332 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTL7A actin-like 7A
ACTN2 actinin, alpha 2
ACTR3BP2 ACTR3B pseudogene 2
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADRBK1 adrenergic, beta, receptor kinase 1
AGO2 argonaute RISC catalytic component 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK3 alpha-kinase 3
AMOT angiomotin
AMT aminomethyltransferase
AOAH acyloxyacyl hydrolase (neutrophil)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP42 Rho GTPase activating protein 42
ARRB1 arrestin, beta 1
ASB16 ankyrin repeat and SOCS box containing 16
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
AURKA aurora kinase A
AURKC aurora kinase C
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BANF1 barrier to autointegration factor 1
C11ORF24 chromosome 11 open reading frame 24
C11ORF30 chromosome 11 open reading frame 30
C1ORF226 chromosome 1 open reading frame 226
C1ORF74 chromosome 1 open reading frame 74
C2CD3 C2 calcium-dependent domain containing 3
C2CD4D C2 calcium-dependent domain containing 4D
C3ORF30 chromosome 3 open reading frame 30
CACUL1 CDK2-associated, cullin domain 1
CACYBP calcyclin binding protein
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CATSPER1 cation channel, sperm associated 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNYL1 cyclin Y-like 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCSAP centriole, cilia and spindle-associated protein
CD300LF CD300 molecule-like family member f
CD68 CD68 molecule
CD84 CD84 molecule
CDC6 cell division cycle 6
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP295 centrosomal protein 295kDa
CEP57 centrosomal protein 57kDa
CES3 carboxylesterase 3
CFL1 cofilin 1 (non-muscle)
CHDH choline dehydrogenase
CHKA choline kinase alpha
CHMP4C charged multivesicular body protein 4C
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CKLF chemokine-like factor
CKS1B CDC28 protein kinase regulatory subunit 1B
CLDN11 claudin 11
CLEC4E C-type lectin domain family 4, member E
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLTC clathrin, heavy chain (Hc)
CMYA5 cardiomyopathy associated 5
CNTN1 contactin 1
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COL2A1 collagen, type II, alpha 1
COMMD7 COMM domain containing 7
COQ6 coenzyme Q6 monooxygenase
CORO1B coronin, actin binding protein, 1B
CPT1C carnitine palmitoyltransferase 1C
CRACR2B calcium release activated channel regulator 2B
CTSC cathepsin C
CTSG cathepsin G
CTSH cathepsin H
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYBB cytochrome b-245, beta polypeptide
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DDIAS DNA damage-induced apoptosis suppressor
DPP3 dipeptidyl-peptidase 3
DPYSL4 dihydropyrimidinase-like 4
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP10 dual specificity phosphatase 10
EED embryonic ectoderm development
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGF epidermal growth factor
EIF1AD eukaryotic translation initiation factor 1A domain containing
ELMO2 engulfment and cell motility 2
ELMO3 engulfment and cell motility 3
ENAM enamelin
ENDOD1 endonuclease domain containing 1
ENO3 enolase 3 (beta, muscle)
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPHA2 EPH receptor A2
EPHA4 EPH receptor A4
EPHX2 epoxide hydrolase 2, cytoplasmic
ESYT1 extended synaptotagmin-like protein 1
FADD Fas (TNFRSF6)-associated via death domain
FASN fatty acid synthase
FCAR Fc fragment of IgA receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FNIP2 folliculin interacting protein 2
FOXA3 forkhead box A3
FPR3 formyl peptide receptor 3
FSCN2 fascin actin-bundling protein 2, retinal
FTH1 ferritin, heavy polypeptide 1
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
FUCA1 fucosidase, alpha-L- 1, tissue
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAL3ST3 galactose-3-O-sulfotransferase 3
GALE UDP-galactose-4-epimerase
GALM galactose mutarotase (aldose 1-epimerase)
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBX2 gastrulation brain homeobox 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GK2 glycerol kinase 2
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1
GPR141 G protein-coupled receptor 141
GPR84 G protein-coupled receptor 84
GSR glutathione reductase
GSS glutathione synthetase
HIST1H1A histone cluster 1, H1a
HOXD1 homeobox D1
HSPA1A heat shock 70kDa protein 1A
HTRA4 HtrA serine peptidase 4
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICOSLG inducible T-cell co-stimulator ligand
IFNLR1 interferon, lambda receptor 1
IGSF6 immunoglobulin superfamily, member 6
IL10RB interleukin 10 receptor, beta
INPPL1 inositol polyphosphate phosphatase-like 1
INSL4 insulin-like 4 (placenta)
IPO9 importin 9
ITPKB inositol-trisphosphate 3-kinase B
IVNS1ABP influenza virus NS1A binding protein
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KCTD14 potassium channel tetramerization domain containing 14
KDM2A lysine (K)-specific demethylase 2A
KDM4D lysine (K)-specific demethylase 4D
KLC2 kinesin light chain 2
KLHL30 kelch-like family member 30
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LCN15 lipocalin 15
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00051 long intergenic non-protein coding RNA 51
LINC00111 long intergenic non-protein coding RNA 111
LINC00112 long intergenic non-protein coding RNA 112
LINC00479 long intergenic non-protein coding RNA 479
LINC01553 long intergenic non-protein coding RNA 1553
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPT2 lipoyl(octanoyl) transferase 2 (putative)
LOC100130093 uncharacterized LOC100130093
LOC100133669 uncharacterized LOC100133669
LOC100134368 uncharacterized LOC100134368
LOC441454 prothymosin, alpha pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LOC81691 exonuclease NEF-sp
LOXL4 lysyl oxidase-like 4
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5 low density lipoprotein receptor-related protein 5
LY6E lymphocyte antigen 6 complex, locus E
MAGEL2 melanoma antigen family L2
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MB21D1 Mab-21 domain containing 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED17 mediator complex subunit 17
MEF2D myocyte enhancer factor 2D
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MICU1 mitochondrial calcium uptake 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP25 matrix metallopeptidase 25
MOAP1 modulator of apoptosis 1
MRC1 mannose receptor, C type 1
MRPL11 mitochondrial ribosomal protein L11
MS4A13 membrane-spanning 4-domains, subfamily A, member 13
MSN moesin
MST1R macrophage stimulating 1 receptor
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTMR2 myotubularin related protein 2
MUS81 MUS81 structure-specific endonuclease subunit
MYO18B myosin XVIIIB
MYO1C myosin IC
MYO1D myosin ID
MYOZ1 myozenin 1
NCALD neurocalcin delta
NCF2 neutrophil cytosolic factor 2
NCOA3 nuclear receptor coactivator 3
NEU3 sialidase 3 (membrane sialidase)
NINJ2 ninjurin 2
NNT nicotinamide nucleotide transhydrogenase
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NSG1 neuron specific gene family member 1
NUMA1 nuclear mitotic apparatus protein 1
OIT3 oncoprotein induced transcript 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSGIN2 oxidative stress induced growth inhibitor family member 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAAF1 proteasomal ATPase-associated factor 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAGE2 P antigen family, member 2 (prostate associated)
PANX1 pannexin 1
PAPOLA poly(A) polymerase alpha
PARP1 poly (ADP-ribose) polymerase 1
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PELI3 pellino E3 ubiquitin protein ligase family member 3
PGAM4 phosphoglycerate mutase family member 4
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PHOX2A paired-like homeobox 2a
PIANP PILR alpha associated neural protein
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPID peptidylprolyl isomerase D
PPME1 protein phosphatase methylesterase 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDX1 peroxiredoxin 1
PROKR1 prokineticin receptor 1
PRX periaxin
PSD pleckstrin and Sec7 domain containing
PTAFR platelet-activating factor receptor
PTPRO protein tyrosine phosphatase, receptor type, O
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB1B RAB1B, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB42 RAB42, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAI1 retinoic acid induced 1
RBM4 RNA binding motif protein 4
RCE1 Ras converting CAAX endopeptidase 1
RELT RELT tumor necrosis factor receptor
RGS1 regulator of G-protein signaling 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RLN2 relaxin 2
RNF115 ring finger protein 115
RNF169 ring finger protein 169
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPN2 ribophorin II
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSPO4 R-spondin 4
SART1 squamous cell carcinoma antigen recognized by T cells
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SESN3 sestrin 3
SF3B2 splicing factor 3b, subunit 2, 145kDa
SIRPB2 signal-regulatory protein beta 2
SLAMF8 SLAM family member 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC51B solute carrier family 51, beta subunit
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOGA1 suppressor of glucose, autophagy associated 1
SOX13 SRY (sex determining region Y)-box 13
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRP68 signal recognition particle 68kDa
SSH3 slingshot protein phosphatase 3
STBD1 starch binding domain 1
STIP1 stress-induced phosphoprotein 1
SYT13 synaptotagmin XIII
TBX18 T-box 18
TDRKH tudor and KH domain containing
TFRC transferrin receptor
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TLDC2 TBC/LysM-associated domain containing 2
TMEM106A transmembrane protein 106A
TMEM134 transmembrane protein 134
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TONSL tonsoku-like, DNA repair protein
TOR1AIP1 torsin A interacting protein 1
TOR1AIP2 torsin A interacting protein 2
TPD52 tumor protein D52
TREML4 triggering receptor expressed on myeloid cells-like 4
TRIB1 tribbles pseudokinase 1
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM67 tripartite motif containing 67
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN14 tetraspanin 14
TSPY26P testis specific protein, Y-linked 26, pseudogene
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTC7B tetratricopeptide repeat domain 7B
TTI1 TELO2 interacting protein 1
TUBA8 tubulin, alpha 8
TULP2 tubby like protein 2
TXNRD1 thioredoxin reductase 1
TYR tyrosinase
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UHMK1 U2AF homology motif (UHM) kinase 1
UNC13D unc-13 homolog D (C. elegans)
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WNK1 WNK lysine deficient protein kinase 1
WNK3 WNK lysine deficient protein kinase 3
XRRA1 X-ray radiation resistance associated 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB8B zinc finger and BTB domain containing 8B
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF217 zinc finger protein 217
ZNF252P zinc finger protein 252, pseudogene
ZNF503 zinc finger protein 503
ZNF620 zinc finger protein 620
ZNF706 zinc finger protein 706
ZNF827 zinc finger protein 827

low expression

Symbol Name
CCDC174 coiled-coil domain containing 174
SMIM7 small integral membrane protein 7