Skin Erosion Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A discontinuity of the skin exhibiting incomplete loss of the epidermis, a lesion that is moist, circumscribed, and usually depressed. (Human Phenotype Ontology, HP_0200041)
External Link https://www.disgenet.org/browser/0/1/0/C3887524
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Genes

209 genes associated with the disease Skin Erosion in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABR active BCR-related
ACR acrosin
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
APOE apolipoprotein E
AREG amphiregulin
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6
ARSD arylsulfatase D
ASCC2 activating signal cointegrator 1 complex subunit 2
ASF1A anti-silencing function 1A histone chaperone
ATM ATM serine/threonine kinase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATR ATR serine/threonine kinase
BEST1 bestrophin 1
BRCA1 breast cancer 1, early onset
CAPG capping protein (actin filament), gelsolin-like
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC103 coiled-coil domain containing 103
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCL8 chemokine (C-C motif) ligand 8
CCN1 cellular communication network factor 1
CCR2 chemokine (C-C motif) receptor 2
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD68 CD68 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRM3 cholinergic receptor, muscarinic 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
CLDN1 claudin 1
CLDN7 claudin 7
CLEC1B C-type lectin domain family 1, member B
CLEC5A C-type lectin domain family 5, member A
CNN2 calponin 2
COL17A1 collagen, type XVII, alpha 1
COL2A1 collagen, type II, alpha 1
COL7A1 collagen, type VII, alpha 1
COMMD1 copper metabolism (Murr1) domain containing 1
COMP cartilage oligomeric matrix protein
CPB1 carboxypeptidase B1 (tissue)
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSF1 colony stimulating factor 1 (macrophage)
CSTA cystatin A (stefin A)
CTSB cathepsin B
CTSK cathepsin K
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CYLD cylindromatosis (turban tumor syndrome)
DMD dystrophin
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
EFL1 elongation factor like GTPase 1
EGF epidermal growth factor
EMP1 epithelial membrane protein 1
EXO1 exonuclease 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOXP3 forkhead box P3
GADD45G growth arrest and DNA-damage-inducible, gamma
GDF15 growth differentiation factor 15
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
H2AX H2A.X variant histone
HAVCR1 hepatitis A virus cellular receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFNL1 interferon, lambda 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL17A interleukin 17A
IL17B interleukin 17B
IL17D interleukin 17D
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL2RB interleukin 2 receptor, beta
IL32 interleukin 32
IL34 interleukin 34
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
IMPACT impact RWD domain protein
IRAK1 interleukin-1 receptor-associated kinase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUP junction plakoglobin
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LMNA lamin A/C
LRP5 low density lipoprotein receptor-related protein 5
MAG myelin associated glycoprotein
MAPK3 mitogen-activated protein kinase 3
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MMUT methylmalonyl-CoA mutase
MPG N-methylpurine-DNA glycosylase
MTX1 metaxin 1
MYDGF myeloid-derived growth factor
NAXE NAD(P)HX epimerase
NBEAL1 neurobeachin-like 1
NCOA5 nuclear receptor coactivator 5
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH1 notch 1
NOX1 NADPH oxidase 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF1 outer dense fiber of sperm tails 1
OMP olfactory marker protein
OSM oncostatin M
PADI4 peptidyl arginine deiminase, type IV
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKP1 plakophilin 1
PLEC plectin
PMEL premelanosome protein
POLG polymerase (DNA directed), gamma
POSTN periostin, osteoblast specific factor
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDM9 PR domain containing 9
PRDX2 peroxiredoxin 2
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51B RAD51 paralog B
RBM45 RNA binding motif protein 45
RMC1 regulator of MON1-CCZ1
RPE65 retinal pigment epithelium-specific protein 65kDa
RTEL1 regulator of telomere elongation helicase 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SH3BP2 SH3-domain binding protein 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SOX5 SRY (sex determining region Y)-box 5
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRI sorcin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STATH statherin
SYK spleen tyrosine kinase
TBPL1 TBP-like 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM5 transglutaminase 5
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TP63 tumor protein p63
TPI1 triosephosphate isomerase 1
TPO thyroid peroxidase
TPX2 TPX2, microtubule-associated
TRAP triiodothyronine receptor auxiliary protein
TSPO translocator protein (18kDa)
TWNK twinkle mtDNA helicase
UBXN11 UBX domain protein 11
UVRAG UV radiation resistance associated
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WIF1 WNT inhibitory factor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZMPSTE24 zinc metallopeptidase STE24