Skin Toxicity Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1167791
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Genes

62 genes associated with the disease Skin Toxicity in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ANTXR2 anthrax toxin receptor 2
AREG amphiregulin
ARG1 arginase 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CA14 carbonic anhydrase XIV
CALCR calcitonin receptor
CALR calreticulin
CCND1 cyclin D1
CDA cytidine deaminase
CLDN1 claudin 1
CLDN2 claudin 2
CLDN4 claudin 4
CXCL8 chemokine (C-X-C motif) ligand 8
DCK deoxycytidine kinase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EREG epiregulin
FANCD2 Fanconi anemia, complementation group D2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
GRM5 glutamate receptor, metabotropic 5
GSTA1 glutathione S-transferase alpha 1
GSTP1 glutathione S-transferase pi 1
HCAR2 hydroxycarboxylic acid receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL1B interleukin 1, beta
IL31 interleukin 31
IL33 interleukin 33
IL6 interleukin 6
JAK2 Janus kinase 2
JAZF1 JAZF zinc finger 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LIFR leukemia inhibitory factor receptor alpha
LIG3 ligase III, DNA, ATP-dependent
MAP2K7 mitogen-activated protein kinase kinase 7
MCC mutated in colorectal cancers
MLH1 mutL homolog 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS3 nitric oxide synthase 3 (endothelial cell)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD51 RAD51 recombinase
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOD2 superoxide dismutase 2, mitochondrial
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)