| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.113507 |
| CDH13 | cadherin 13 | 0.110355 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0909066 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.082266 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0777401 |
| COL5A1 | collagen, type V, alpha 1 | 0.0631061 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0551694 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0468022 |
| FN1 | fibronectin 1 | 0.0458226 |
| EGFR | epidermal growth factor receptor | 0.0449021 |
| MAP1B | microtubule-associated protein 1B | 0.0445116 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0442285 |
| FLNA | filamin A, alpha | 0.0365135 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0360268 |
| EFNA5 | ephrin-A5 | 0.034976 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0344967 |
| POTEF | POTE ankyrin domain family, member F | 0.0314778 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0296171 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0287005 |
| CCND1 | cyclin D1 | 0.0286659 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0285929 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0284013 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0279316 |
| PLEC | plectin | 0.0278891 |
| FSTL1 | follistatin-like 1 | 0.0278848 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278288 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0273876 |
| HDAC9 | histone deacetylase 9 | 0.0271387 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269825 |
| PLAT | plasminogen activator, tissue | 0.0264501 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0259903 |
| TPM4 | tropomyosin 4 | 0.025118 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.024785 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0246753 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0243945 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0233935 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0228886 |
| SUCNR1 | succinate receptor 1 | 0.0225851 |
| PLXNA2 | plexin A2 | 0.0218681 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0214612 |
| RND3 | Rho family GTPase 3 | 0.0214334 |
| GOLGB1 | golgin B1 | 0.0210986 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0208631 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0203869 |
| VEGFA | vascular endothelial growth factor A | 0.0202144 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0201563 |
| CENPF | centromere protein F, 350/400kDa | 0.019975 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0189825 |
| CYTH3 | cytohesin 3 | 0.0188158 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0186242 |
| FOSL1 | FOS-like antigen 1 | 0.0184936 |
| MSN | moesin | 0.018428 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0183002 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.017889 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0178461 |
| LMNA | lamin A/C | 0.0175021 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0171022 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0170797 |
| SEPTIN9 | septin 9 | 0.0170526 |
| INTS6 | integrator complex subunit 6 | 0.0165678 |
| ANKRD30B | ankyrin repeat domain 30B | 0.016547 |
| BCL2L1 | BCL2-like 1 | 0.016448 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0164441 |
| MSI2 | musashi RNA-binding protein 2 | 0.0164073 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0160346 |
| CSTB | cystatin B (stefin B) | 0.0159522 |
| ASPH | aspartate beta-hydroxylase | 0.0156605 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0152478 |
| KRT81 | keratin 81, type II | 0.0152305 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0148642 |
| FMN2 | formin 2 | 0.0147342 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0145934 |
| TOX | thymocyte selection-associated high mobility group box | 0.0145473 |
| CUX1 | cut-like homeobox 1 | 0.0144935 |
| RPL35A | ribosomal protein L35a | 0.0143771 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.014254 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0139184 |
| KIAA1549L | KIAA1549-like | 0.0138701 |
| FTL | ferritin, light polypeptide | 0.0136076 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0134862 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.0134205 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0133677 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 0.0133461 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0132288 |
| HM13 | histocompatibility (minor) 13 | 0.0130379 |
| CALD1 | caldesmon 1 | 0.0127196 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0127066 |
| IL7R | interleukin 7 receptor | 0.0124717 |
| TUBB4B | tubulin, beta 4B class IVb | 0.012453 |
| L1CAM | L1 cell adhesion molecule | 0.012413 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0122228 |
| VEGFC | vascular endothelial growth factor C | 0.0122119 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0120674 |
| NCOR2 | nuclear receptor corepressor 2 | 0.011795 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0117118 |
| ACTG1 | actin gamma 1 | 0.0117069 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0114884 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0113591 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0110271 |
| NAV1 | neuron navigator 1 | 0.0109732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.169025 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.15623 |
| FBN1 | fibrillin 1 | -0.133753 |
| COL3A1 | collagen, type III, alpha 1 | -0.121818 |
| TMSB10 | thymosin beta 10 | -0.106699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0972654 |
| MT2A | metallothionein 2A | -0.0958929 |
| COL1A2 | collagen, type I, alpha 2 | -0.0795347 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0795197 |
| LOX | lysyl oxidase | -0.0783083 |
| COL5A2 | collagen, type V, alpha 2 | -0.0717816 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0671636 |
| CD44 | CD44 molecule (Indian blood group) | -0.0651082 |
| OGA | O-GlcNAcase | -0.0580865 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0554281 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0529909 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0522864 |
| VIM | vimentin | -0.0510239 |
| STC1 | stanniocalcin 1 | -0.048896 |
| AHNAK | AHNAK nucleoprotein | -0.0484545 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0455084 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0435115 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.041848 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0416668 |
| APP | amyloid beta (A4) precursor protein | -0.0415758 |
| B2M | beta-2-microglobulin | -0.0408125 |
| ANXA2 | annexin A2 | -0.0388695 |
| SBF2 | SET binding factor 2 | -0.0381054 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.03752 |
| GPC6 | glypican 6 | -0.0369661 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.036501 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0358518 |
| LOXL2 | lysyl oxidase-like 2 | -0.0356342 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0350561 |
| PTMA | prothymosin, alpha | -0.0347889 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0336664 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0332915 |
| MT1X | metallothionein 1X | -0.0332646 |
| ATP13A3 | ATPase type 13A3 | -0.0330004 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0326862 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0313663 |
| AUTS2 | autism susceptibility candidate 2 | -0.0305277 |
| LDHA | lactate dehydrogenase A | -0.0303151 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293961 |
| FLNB | filamin B, beta | -0.0290617 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.028625 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0281215 |
| CD99 | CD99 molecule | -0.0281077 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.028027 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.027963 |
| THBS2 | thrombospondin 2 | -0.0276361 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0271757 |
| XPO1 | exportin 1 | -0.0270282 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0267245 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266342 |
| RPS27A | ribosomal protein S27a | -0.0263888 |
| KIFAP3 | kinesin-associated protein 3 | -0.0263525 |
| TXNIP | thioredoxin interacting protein | -0.0263333 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0260105 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0260052 |
| RBM25 | RNA binding motif protein 25 | -0.0256684 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0252567 |
| ARRDC3 | arrestin domain containing 3 | -0.0249642 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0248535 |
| PCBP2 | poly(rC) binding protein 2 | -0.024439 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0242686 |
| DENND5A | DENN/MADD domain containing 5A | -0.0239392 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.023939 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0237865 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0236991 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0232676 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0229533 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0229249 |
| WTAP | Wilms tumor 1 associated protein | -0.0224853 |
| SDC4 | syndecan 4 | -0.0223612 |
| ACTN4 | actinin, alpha 4 | -0.0219934 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0218553 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.021696 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0215504 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.021407 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.020832 |
| ENO1 | enolase 1, (alpha) | -0.0207614 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0202275 |
| TMOD1 | tropomodulin 1 | -0.0200127 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0198271 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0197973 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0197178 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0197085 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0196108 |
| TRIM56 | tripartite motif containing 56 | -0.0194248 |
| HMGB2 | high mobility group box 2 | -0.0192209 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0191636 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0189665 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0189527 |
| CANX | calnexin | -0.0188826 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0186522 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0185008 |
| TAGLN2 | transgelin 2 | -0.0184477 |
| TMSB4X | thymosin beta 4, X-linked | -0.0183813 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0181143 |