| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0325751 |
| RRM2 | ribonucleotide reductase M2 | 0.0270327 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0255327 |
| INTS6 | integrator complex subunit 6 | 0.0241709 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0221135 |
| WWOX | WW domain containing oxidoreductase | 0.0184303 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0176759 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0155673 |
| CCNL1 | cyclin L1 | 0.015416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0151416 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0148808 |
| PCM1 | pericentriolar material 1 | 0.0147301 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0144774 |
| RPS4X | ribosomal protein S4, X-linked | 0.0143453 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0135571 |
| EPHA6 | EPH receptor A6 | 0.0134488 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0133007 |
| HELLS | helicase, lymphoid-specific | 0.0130675 |
| FLNA | filamin A, alpha | 0.0128772 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0126939 |
| MGAT4C | MGAT4 family, member C | 0.0125109 |
| PHF3 | PHD finger protein 3 | 0.0125057 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0124528 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0123976 |
| CPOX | coproporphyrinogen oxidase | 0.0120572 |
| NEGR1 | neuronal growth regulator 1 | 0.0118348 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0116945 |
| CCDC88A | coiled-coil domain containing 88A | 0.0115931 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0115724 |
| YAP1 | Yes-associated protein 1 | 0.0113909 |
| ZNF292 | zinc finger protein 292 | 0.010932 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0109223 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.010669 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0105144 |
| ZNF638 | zinc finger protein 638 | 0.0103692 |
| BRD2 | bromodomain containing 2 | 0.0102566 |
| IFT80 | intraflagellar transport 80 | 0.0100216 |
| NFIB | nuclear factor I/B | 0.00987179 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0098144 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00967058 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.00958965 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00949293 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00947271 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00925041 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00924844 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00922506 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00920833 |
| FLNB | filamin B, beta | 0.00913355 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0090608 |
| OXR1 | oxidation resistance 1 | 0.00904939 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00901018 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00893716 |
| IPMK | inositol polyphosphate multikinase | 0.00882716 |
| PEG10 | paternally expressed 10 | 0.00879476 |
| POLK | polymerase (DNA directed) kappa | 0.0087034 |
| MMS22L | MMS22-like, DNA repair protein | 0.00867659 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00867377 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00864729 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00864252 |
| WDR26 | WD repeat domain 26 | 0.0086284 |
| DENND5A | DENN/MADD domain containing 5A | 0.00862356 |
| NKTR | natural killer cell triggering receptor | 0.00856345 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00854747 |
| MSH6 | mutS homolog 6 | 0.00851521 |
| SFTPA2 | surfactant protein A2 | 0.00847028 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00841876 |
| SMC6 | structural maintenance of chromosomes 6 | 0.00838866 |
| CLSPN | claspin | 0.00837701 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00835708 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.00832152 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.00831782 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.00830293 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.00828247 |
| RAD51B | RAD51 paralog B | 0.00827259 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.00823611 |
| HELZ | helicase with zinc finger | 0.00823376 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00821616 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.00820584 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00817151 |
| POU2F1 | POU class 2 homeobox 1 | 0.00815352 |
| CCDC14 | coiled-coil domain containing 14 | 0.00814756 |
| OGA | O-GlcNAcase | 0.00809861 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0080649 |
| PLEC | plectin | 0.0080409 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00804056 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.00799284 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.00794263 |
| YBX3 | Y box binding protein 3 | 0.00789632 |
| MACROD2 | MACRO domain containing 2 | 0.00787929 |
| STYK1 | serine/threonine/tyrosine kinase 1 | 0.00783748 |
| STRN | striatin, calmodulin binding protein | 0.0077661 |
| CEP70 | centrosomal protein 70kDa | 0.00775869 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.00775237 |
| FBXO38 | F-box protein 38 | 0.00773404 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.00761884 |
| NCKAP1 | NCK-associated protein 1 | 0.00761785 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.00761768 |
| PRELID2 | PRELI domain containing 2 | 0.00750393 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.00750201 |
| PER1 | period circadian clock 1 | 0.00748717 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.205964 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.163924 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131565 |
| NLGN1 | neuroligin 1 | -0.105005 |
| PTMA | prothymosin, alpha | -0.0925343 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0917524 |
| MMP12 | matrix metallopeptidase 12 | -0.0668763 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.066217 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0621964 |
| ACTG1 | actin gamma 1 | -0.0603043 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0591202 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0578051 |
| EHBP1 | EH domain binding protein 1 | -0.056621 |
| RASAL2 | RAS protein activator like 2 | -0.0566055 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0515823 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0498952 |
| TMSB10 | thymosin beta 10 | -0.0480267 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0478507 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0478256 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0472237 |
| TMEM41B | transmembrane protein 41B | -0.0467354 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0459361 |
| SLC38A1 | solute carrier family 38, member 1 | -0.045251 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0451318 |
| USP34 | ubiquitin specific peptidase 34 | -0.0443534 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0441419 |
| ASPH | aspartate beta-hydroxylase | -0.0430949 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0430529 |
| BCHE | butyrylcholinesterase | -0.0412885 |
| RPL35A | ribosomal protein L35a | -0.0412107 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.041203 |
| NHSL1 | NHS-like 1 | -0.0400656 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0392699 |
| CLDN1 | claudin 1 | -0.0382108 |
| ENO1 | enolase 1, (alpha) | -0.0363817 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0363146 |
| JMJD1C | jumonji domain containing 1C | -0.0362941 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0358898 |
| RPS8 | ribosomal protein S8 | -0.0355998 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0352576 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0350897 |
| CMIP | c-Maf inducing protein | -0.0330746 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0329909 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0329171 |
| ANXA1 | annexin A1 | -0.0329135 |
| FTL | ferritin, light polypeptide | -0.0328808 |
| ZNF804A | zinc finger protein 804A | -0.0326689 |
| MKI67 | marker of proliferation Ki-67 | -0.0304116 |
| S100A6 | S100 calcium binding protein A6 | -0.0303553 |
| CALR | calreticulin | -0.0300682 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0300422 |
| PCDH7 | protocadherin 7 | -0.029264 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0291611 |
| NAV3 | neuron navigator 3 | -0.029127 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0288414 |
| LMO7 | LIM domain 7 | -0.0284251 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0280021 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276455 |
| TPM4 | tropomyosin 4 | -0.0275406 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0273378 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0272366 |
| EDARADD | EDAR-associated death domain | -0.0270115 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0263936 |
| RPS29 | ribosomal protein S29 | -0.0263158 |
| VMP1 | vacuole membrane protein 1 | -0.0262525 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0258113 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0257808 |
| RPL37A | ribosomal protein L37a | -0.0257262 |
| RPS27A | ribosomal protein S27a | -0.0256555 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0254382 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0252202 |
| NEBL | nebulette | -0.0250309 |
| RPS13 | ribosomal protein S13 | -0.0249902 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0249749 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0246584 |
| CUX1 | cut-like homeobox 1 | -0.0245578 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0245116 |
| EGR1 | early growth response 1 | -0.0244874 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.024477 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0240479 |
| MAP4 | microtubule-associated protein 4 | -0.0240026 |
| CANX | calnexin | -0.0237466 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0235977 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0230454 |
| TUBA1B | tubulin, alpha 1b | -0.0229432 |
| NF1 | neurofibromin 1 | -0.022813 |
| LDHA | lactate dehydrogenase A | -0.0227942 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0222773 |
| RPL37 | ribosomal protein L37 | -0.022235 |
| TGM2 | transglutaminase 2 | -0.0215683 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0215212 |
| HSPB1 | heat shock 27kDa protein 1 | -0.021476 |
| PGK1 | phosphoglycerate kinase 1 | -0.0211103 |
| RPS3 | ribosomal protein S3 | -0.0208375 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0208261 |
| S100A10 | S100 calcium binding protein A10 | -0.0207404 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0207075 |
| TMEM123 | transmembrane protein 123 | -0.0206226 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0205345 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0204139 |
