| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0821423 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0793265 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0687084 |
| MSN | moesin | 0.0685265 |
| NAV2 | neuron navigator 2 | 0.0591648 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0497164 |
| PLEC | plectin | 0.0457308 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0408627 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0399406 |
| PAX8 | paired box 8 | 0.0391889 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0389389 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0380722 |
| VEGFA | vascular endothelial growth factor A | 0.0379853 |
| TPM3 | tropomyosin 3 | 0.0378056 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0374 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0373854 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0366032 |
| SEPTIN9 | septin 9 | 0.0359554 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0353938 |
| TGM2 | transglutaminase 2 | 0.0330521 |
| RND3 | Rho family GTPase 3 | 0.0313409 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0300447 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0295166 |
| FMNL2 | formin-like 2 | 0.0294938 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0291393 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0289553 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0284067 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0278171 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0275585 |
| NOTCH2 | notch 2 | 0.0262664 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0258251 |
| CADM1 | cell adhesion molecule 1 | 0.0250095 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0247598 |
| OPTN | optineurin | 0.0237047 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0225086 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0224993 |
| COG6 | component of oligomeric golgi complex 6 | 0.0223851 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223348 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0219774 |
| FLNA | filamin A, alpha | 0.0219366 |
| TLN1 | talin 1 | 0.0218641 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0216476 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0209377 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0208452 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0206668 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0205645 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0204805 |
| HDGF | hepatoma-derived growth factor | 0.0202046 |
| POTEF | POTE ankyrin domain family, member F | 0.0197338 |
| COL5A1 | collagen, type V, alpha 1 | 0.0194213 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0189978 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0186716 |
| HDAC9 | histone deacetylase 9 | 0.0185784 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0184404 |
| EGFR | epidermal growth factor receptor | 0.01806 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0179055 |
| MYADM | myeloid-associated differentiation marker | 0.0178286 |
| COPA | coatomer protein complex, subunit alpha | 0.0178029 |
| SETD5 | SET domain containing 5 | 0.0174503 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0174385 |
| STOM | stomatin | 0.0174281 |
| TNS1 | tensin 1 | 0.0173777 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0173491 |
| CDK6 | cyclin-dependent kinase 6 | 0.0173324 |
| XPO1 | exportin 1 | 0.0173254 |
| RPL3 | ribosomal protein L3 | 0.0170111 |
| SPAG9 | sperm associated antigen 9 | 0.0167317 |
| PGM3 | phosphoglucomutase 3 | 0.0166191 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0165062 |
| PML | promyelocytic leukemia | 0.0164349 |
| AHNAK | AHNAK nucleoprotein | 0.0163491 |
| RUNX1 | runt-related transcription factor 1 | 0.0161784 |
| INTS6 | integrator complex subunit 6 | 0.016139 |
| SUCO | SUN domain containing ossification factor | 0.0160522 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0160361 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0159321 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0159319 |
| GSPT1 | G1 to S phase transition 1 | 0.0159086 |
| BRD4 | bromodomain containing 4 | 0.0158316 |
| HYOU1 | hypoxia up-regulated 1 | 0.0157872 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0157651 |
| FBRS | fibrosin | 0.0157328 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0156113 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0155247 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0154078 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0153742 |
| MCL1 | myeloid cell leukemia 1 | 0.0153301 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0151662 |
| ANO6 | anoctamin 6 | 0.0150352 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0149882 |
| ATP13A3 | ATPase type 13A3 | 0.0149268 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.014881 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0148325 |
| MNT | MAX network transcriptional repressor | 0.0146783 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0146589 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0146393 |
| CTBP2 | C-terminal binding protein 2 | 0.0145873 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0145622 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0145412 |
| USP47 | ubiquitin specific peptidase 47 | 0.0145223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.151088 |
| VIM | vimentin | -0.125842 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114263 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.111283 |
| FTL | ferritin, light polypeptide | -0.109691 |
| TMSB10 | thymosin beta 10 | -0.106807 |
| HLA-B | major histocompatibility complex, class I, B | -0.0935505 |
| GLIS3 | GLIS family zinc finger 3 | -0.0929685 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0815129 |
| CP | ceruloplasmin (ferroxidase) | -0.0792708 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0723822 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0698783 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0618835 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0602586 |
| TXNRD1 | thioredoxin reductase 1 | -0.0580414 |
| RRBP1 | ribosome binding protein 1 | -0.0574877 |
| CA12 | carbonic anhydrase XII | -0.0561517 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0539218 |
| B2M | beta-2-microglobulin | -0.0531768 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0511734 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0472512 |
| STK17A | serine/threonine kinase 17a | -0.0466989 |
| UBC | ubiquitin C | -0.0457591 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.045353 |
| MT2A | metallothionein 2A | -0.0436333 |
| RPL26 | ribosomal protein L26 | -0.043616 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0410685 |
| RPS24 | ribosomal protein S24 | -0.0406304 |
| CD44 | CD44 molecule (Indian blood group) | -0.0396754 |
| TGFA | transforming growth factor, alpha | -0.0396621 |
| OSMR | oncostatin M receptor | -0.0395887 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0395762 |
| ARF1 | ADP-ribosylation factor 1 | -0.0392789 |
| FRMD4A | FERM domain containing 4A | -0.0392031 |
| PTMA | prothymosin, alpha | -0.0381784 |
| RPL35A | ribosomal protein L35a | -0.0374999 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0374383 |
| RPS6 | ribosomal protein S6 | -0.0371737 |
| ACTG1 | actin gamma 1 | -0.03712 |
| GDF15 | growth differentiation factor 15 | -0.0368551 |
| RPL31 | ribosomal protein L31 | -0.0367337 |
| LDHA | lactate dehydrogenase A | -0.0365195 |
| PALLD | palladin, cytoskeletal associated protein | -0.0363709 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0357569 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0355425 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0354503 |
| RPL12 | ribosomal protein L12 | -0.0354404 |
| RPL34 | ribosomal protein L34 | -0.0350798 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0345942 |
| RPLP2 | ribosomal protein, large, P2 | -0.0344472 |
| RPS8 | ribosomal protein S8 | -0.0343969 |
| APOL1 | apolipoprotein L, 1 | -0.0343013 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0341677 |
| HLA-C | major histocompatibility complex, class I, C | -0.0340752 |
| RPL23 | ribosomal protein L23 | -0.034031 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0339027 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0337374 |
| RPS19 | ribosomal protein S19 | -0.0331182 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324945 |
| LOXL2 | lysyl oxidase-like 2 | -0.0324094 |
| NF1 | neurofibromin 1 | -0.0323796 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0323044 |
| CAVIN1 | caveolae associated protein 1 | -0.0316108 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0311848 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0308575 |
| RPS5 | ribosomal protein S5 | -0.0308298 |
| RPL30 | ribosomal protein L30 | -0.0306177 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305663 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0305377 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0295225 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -0.0293393 |
| MTDH | metadherin | -0.0292251 |
| EHBP1 | EH domain binding protein 1 | -0.02903 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0285459 |
| RPS27A | ribosomal protein S27a | -0.0283354 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0274097 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0272838 |
| GNAS | GNAS complex locus | -0.0272491 |
| ETV6 | ets variant 6 | -0.0272121 |
| FUS | FUS RNA binding protein | -0.0270594 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0269716 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0269495 |
| H3-3B | H3.3 histone B | -0.0265147 |
| PTGR1 | prostaglandin reductase 1 | -0.0262615 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0260247 |
| RPL37 | ribosomal protein L37 | -0.0254858 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0254149 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0251893 |
| RPL37A | ribosomal protein L37a | -0.0250998 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0250186 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0247596 |
| RPL7 | ribosomal protein L7 | -0.0247078 |
| CD63 | CD63 molecule | -0.0247057 |
| RBM39 | RNA binding motif protein 39 | -0.0246447 |
| RPL36A | ribosomal protein L36a | -0.0245538 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0244944 |
| RPL38 | ribosomal protein L38 | -0.0243237 |
| RPS21 | ribosomal protein S21 | -0.0242119 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0241188 |
