| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.125784 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0588036 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0510788 |
| VCL | vinculin | 0.038263 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0380632 |
| INTS6 | integrator complex subunit 6 | 0.0337139 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0337059 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0330634 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0309181 |
| TGM2 | transglutaminase 2 | 0.0298919 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0297841 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.02943 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0268252 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0266133 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0258361 |
| DUSP5 | dual specificity phosphatase 5 | 0.0241266 |
| RNF145 | ring finger protein 145 | 0.0240474 |
| USP3 | ubiquitin specific peptidase 3 | 0.0237887 |
| RHCG | Rh family, C glycoprotein | 0.0221438 |
| BMP6 | bone morphogenetic protein 6 | 0.0219699 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0218104 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0217894 |
| AADAC | arylacetamide deacetylase | 0.0204215 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0198294 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0193485 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0184678 |
| SMAD3 | SMAD family member 3 | 0.0182449 |
| VEGFA | vascular endothelial growth factor A | 0.0174539 |
| CCNL1 | cyclin L1 | 0.0172867 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0171456 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0170788 |
| KYNU | kynureninase | 0.0169593 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0169284 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0169059 |
| FLNA | filamin A, alpha | 0.016798 |
| FERMT2 | fermitin family member 2 | 0.0165448 |
| LMO7 | LIM domain 7 | 0.0157596 |
| VEGFC | vascular endothelial growth factor C | 0.0156112 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0153763 |
| ETNK1 | ethanolamine kinase 1 | 0.0151383 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0150756 |
| NABP1 | nucleic acid binding protein 1 | 0.0150256 |
| NTN4 | netrin 4 | 0.0149001 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0144842 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0144447 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0140585 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0139865 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0139092 |
| MAP7 | microtubule-associated protein 7 | 0.0138073 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.01352 |
| SEPTIN9 | septin 9 | 0.01346 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.013182 |
| AUTS2 | autism susceptibility candidate 2 | 0.0130949 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0128615 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0125488 |
| ZFP36 | ZFP36 ring finger protein | 0.012459 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0122892 |
| PLEC | plectin | 0.0122066 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0116795 |
| MSN | moesin | 0.0115725 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0114842 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0114813 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0114654 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0113892 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0112583 |
| HELZ | helicase with zinc finger | 0.0112565 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0109512 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0108791 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0107965 |
| RPS2 | ribosomal protein S2 | 0.0107594 |
| ITGB4 | integrin, beta 4 | 0.0106971 |
| HMGA2 | high mobility group AT-hook 2 | 0.0105815 |
| FOSL2 | FOS-like antigen 2 | 0.0105673 |
| CDKL5 | cyclin-dependent kinase-like 5 | 0.010542 |
| TGFB1 | transforming growth factor, beta 1 | 0.0104812 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0103965 |
| PALLD | palladin, cytoskeletal associated protein | 0.0103961 |
| LAMA5 | laminin, alpha 5 | 0.0103003 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0102332 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0101072 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.010078 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0100732 |
| MOSMO | modulator of smoothened | 0.0100028 |
| RSU1 | Ras suppressor protein 1 | 0.00999983 |
| ECT2 | epithelial cell transforming 2 | 0.00983261 |
| NHSL1 | NHS-like 1 | 0.00977444 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00964956 |
| WWC1 | WW and C2 domain containing 1 | 0.00951713 |
| USP53 | ubiquitin specific peptidase 53 | 0.00949315 |
| LOXL2 | lysyl oxidase-like 2 | 0.00926644 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00918422 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00917458 |
| CAPRIN2 | caprin family member 2 | 0.00907204 |
| AGRN | agrin | 0.00891218 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0089085 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0088169 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00878926 |
| GPATCH2L | G patch domain containing 2-like | 0.00872749 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00871423 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.00867613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.230157 |
| VIM | vimentin | -0.221661 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12495 |
| ACTG1 | actin gamma 1 | -0.121485 |
| UBC | ubiquitin C | -0.120878 |
| ANXA2 | annexin A2 | -0.107295 |
| RPS27A | ribosomal protein S27a | -0.100219 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.094605 |
| PTMA | prothymosin, alpha | -0.0932583 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0898177 |
| MT2A | metallothionein 2A | -0.087958 |
| CA12 | carbonic anhydrase XII | -0.0861969 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0850071 |
| ENO1 | enolase 1, (alpha) | -0.0763924 |
| AHNAK | AHNAK nucleoprotein | -0.0744725 |
| RPS19 | ribosomal protein S19 | -0.0744117 |
| KRT81 | keratin 81, type II | -0.07316 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0730712 |
| RPLP1 | ribosomal protein, large, P1 | -0.070181 |
| TXNRD1 | thioredoxin reductase 1 | -0.0691408 |
| RPS16 | ribosomal protein S16 | -0.0690048 |
| S100A6 | S100 calcium binding protein A6 | -0.0687581 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0675697 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0671652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0667615 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0649818 |
| RPL23 | ribosomal protein L23 | -0.0635365 |
| LDHA | lactate dehydrogenase A | -0.062838 |
| FAM107B | family with sequence similarity 107, member B | -0.0616121 |
| RPS24 | ribosomal protein S24 | -0.0573356 |
| RPS6 | ribosomal protein S6 | -0.0572906 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0566004 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0558315 |
| FLNB | filamin B, beta | -0.0529526 |
| OSMR | oncostatin M receptor | -0.0525289 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0522003 |
| RPS3 | ribosomal protein S3 | -0.0501503 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0499471 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0495772 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0484583 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0482004 |
| PGK1 | phosphoglycerate kinase 1 | -0.0477027 |
| RPL12 | ribosomal protein L12 | -0.046287 |
| CANX | calnexin | -0.0458986 |
| FTL | ferritin, light polypeptide | -0.0458129 |
| RPS13 | ribosomal protein S13 | -0.0455298 |
| S100A10 | S100 calcium binding protein A10 | -0.0453232 |
| RPL26 | ribosomal protein L26 | -0.0446511 |
| SBF2 | SET binding factor 2 | -0.0440686 |
| RPL37A | ribosomal protein L37a | -0.043798 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0418126 |
| ASPH | aspartate beta-hydroxylase | -0.0416213 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0414992 |
| PKM | pyruvate kinase, muscle | -0.0398483 |
| RPS8 | ribosomal protein S8 | -0.0397177 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.038993 |
| RPL31 | ribosomal protein L31 | -0.0388817 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0382963 |
| MT1X | metallothionein 1X | -0.0382659 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0379101 |
| EFNA5 | ephrin-A5 | -0.0364309 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0364009 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0363212 |
| TPM4 | tropomyosin 4 | -0.0359688 |
| RPL4 | ribosomal protein L4 | -0.0358403 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0351836 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0351386 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0349307 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0347966 |
| RPL35A | ribosomal protein L35a | -0.0346203 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342767 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0341762 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0339056 |
| TMSB4X | thymosin beta 4, X-linked | -0.0338059 |
| RTN4 | reticulon 4 | -0.0337629 |
| RPL36A | ribosomal protein L36a | -0.0332808 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0328792 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0326228 |
| RRBP1 | ribosome binding protein 1 | -0.0322495 |
| USP34 | ubiquitin specific peptidase 34 | -0.0320839 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0320775 |
| NDRG1 | N-myc downstream regulated 1 | -0.0320428 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0319103 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0317712 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0315519 |
| KRT7 | keratin 7, type II | -0.031417 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0312206 |
| JMJD1C | jumonji domain containing 1C | -0.0310498 |
| RPLP2 | ribosomal protein, large, P2 | -0.0305031 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0304318 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.030084 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0298634 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0298556 |
| RPL8 | ribosomal protein L8 | -0.0295545 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0294833 |
| APP | amyloid beta (A4) precursor protein | -0.0293578 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0293259 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0287931 |
| CALU | calumenin | -0.0286082 |
| ANXA4 | annexin A4 | -0.0280567 |
