| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.0701763 |
| INTS6 | integrator complex subunit 6 | 0.0688243 |
| CEP250 | centrosomal protein 250kDa | 0.058712 |
| CDK12 | cyclin-dependent kinase 12 | 0.0525136 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0466485 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0457479 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0431361 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0420306 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0413254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0393198 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0384061 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0377751 |
| MCL1 | myeloid cell leukemia 1 | 0.0368401 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0331148 |
| DTNA | dystrobrevin, alpha | 0.0328549 |
| PLSCR2 | phospholipid scramblase 2 | 0.0321031 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0310333 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0300286 |
| PTK2 | protein tyrosine kinase 2 | 0.029876 |
| VCL | vinculin | 0.0268996 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0265774 |
| FAM168A | family with sequence similarity 168, member A | 0.026318 |
| SP100 | SP100 nuclear antigen | 0.026133 |
| VEGFA | vascular endothelial growth factor A | 0.0261297 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0259158 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0256341 |
| VCP | valosin containing protein | 0.0249231 |
| STXBP4 | syntaxin binding protein 4 | 0.024894 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0245359 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0244018 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0240496 |
| DENND1A | DENN/MADD domain containing 1A | 0.0239096 |
| PRELID2 | PRELI domain containing 2 | 0.0230703 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0230242 |
| KRT86 | keratin 86, type II | 0.0230113 |
| PLEC | plectin | 0.0230107 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0229892 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0228437 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0224537 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0220799 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.021916 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0214024 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212978 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0212404 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.021108 |
| RAD51B | RAD51 paralog B | 0.0209453 |
| GOLGB1 | golgin B1 | 0.0206955 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0206573 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0205637 |
| DENND5A | DENN/MADD domain containing 5A | 0.0205111 |
| KRT18 | keratin 18, type I | 0.0205051 |
| RPL37A | ribosomal protein L37a | 0.0204589 |
| RCOR1 | REST corepressor 1 | 0.0204484 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0201597 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0200553 |
| VMP1 | vacuole membrane protein 1 | 0.0200493 |
| AEBP2 | AE binding protein 2 | 0.0198106 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0197543 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0197466 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0196833 |
| CCNY | cyclin Y | 0.0196787 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0196754 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0195392 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0193474 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.019312 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0191543 |
| YAP1 | Yes-associated protein 1 | 0.0190967 |
| ADIPOR2 | adiponectin receptor 2 | 0.0188529 |
| PARD3 | par-3 family cell polarity regulator | 0.0188459 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0186509 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0185499 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0183423 |
| RTN3 | reticulon 3 | 0.0182668 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0181217 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0180983 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0180669 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0180019 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0177042 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0174733 |
| CDK13 | cyclin-dependent kinase 13 | 0.0172872 |
| USO1 | USO1 vesicle transport factor | 0.0172442 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.017144 |
| EXOC4 | exocyst complex component 4 | 0.017088 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0170434 |
| SBF2 | SET binding factor 2 | 0.0169967 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0169779 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0168775 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.01684 |
| UBAP2 | ubiquitin associated protein 2 | 0.0168086 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0166433 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0165983 |
| FOXO3 | forkhead box O3 | 0.0165541 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0165323 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0164516 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0162336 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0162111 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0161775 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0159093 |
| MED13 | mediator complex subunit 13 | 0.0158909 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.015685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.115538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.074205 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0524772 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0467402 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0444161 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0405373 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0404769 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0386983 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0383623 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0365031 |
| TMSB10 | thymosin beta 10 | -0.036228 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0356902 |
| OSMR | oncostatin M receptor | -0.0354616 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0353983 |
| LDHA | lactate dehydrogenase A | -0.0347041 |
| RPL19 | ribosomal protein L19 | -0.033269 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0324949 |
| CCNI | cyclin I | -0.0324387 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.031324 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.030412 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0303426 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0300238 |
| TMSB4X | thymosin beta 4, X-linked | -0.0284179 |
| RPL12 | ribosomal protein L12 | -0.027621 |
| S100A9 | S100 calcium binding protein A9 | -0.0274771 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0258248 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0255557 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250267 |
| ACTG1 | actin gamma 1 | -0.0247377 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.02463 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0245305 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0242517 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0241113 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0231455 |
| CBX3 | chromobox homolog 3 | -0.0226149 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0225392 |
| TMEM123 | transmembrane protein 123 | -0.0225229 |
| RPL35A | ribosomal protein L35a | -0.0224376 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0223724 |
| RPLP0 | ribosomal protein, large, P0 | -0.0222324 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0221912 |
| CCND1 | cyclin D1 | -0.0220529 |
| UBC | ubiquitin C | -0.0217939 |
| NTN4 | netrin 4 | -0.021782 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0215238 |
| DUSP4 | dual specificity phosphatase 4 | -0.0214986 |
| S100A8 | S100 calcium binding protein A8 | -0.0206998 |
| MT2A | metallothionein 2A | -0.0206705 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0206555 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0203357 |
| KRT19 | keratin 19, type I | -0.0202991 |
| PTMA | prothymosin, alpha | -0.0202208 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0202019 |
| TMEM165 | transmembrane protein 165 | -0.0201739 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0201325 |
| PFDN4 | prefoldin subunit 4 | -0.0199851 |
| TMEM45B | transmembrane protein 45B | -0.0191848 |
| S100A6 | S100 calcium binding protein A6 | -0.0188009 |
| TPI1 | triosephosphate isomerase 1 | -0.0187523 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0186504 |
| RPS19 | ribosomal protein S19 | -0.0185745 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0182569 |
| KLF6 | Kruppel-like factor 6 | -0.0182541 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0182532 |
| DSTN | destrin (actin depolymerizing factor) | -0.018031 |
| TMC5 | transmembrane channel-like 5 | -0.0179549 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0177594 |
| PRR11 | proline rich 11 | -0.0174373 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0172437 |
| NIPSNAP2 | nipsnap homolog 2 | -0.017216 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0171387 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0169715 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0168079 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0167572 |
| GATA3 | GATA binding protein 3 | -0.0166446 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0164609 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.016226 |
| PGK1 | phosphoglycerate kinase 1 | -0.0162132 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0162068 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0160078 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0159662 |
| CLTC | clathrin, heavy chain (Hc) | -0.0159473 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0159215 |
| CD164 | CD164 molecule, sialomucin | -0.0158731 |
| PFN1 | profilin 1 | -0.0158415 |
| SERINC3 | serine incorporator 3 | -0.0157888 |
| ASPH | aspartate beta-hydroxylase | -0.0156919 |
| RPL30 | ribosomal protein L30 | -0.0153837 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0153711 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0153598 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0151915 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0151716 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0148647 |
| RESF1 | retroelement silencing factor 1 | -0.0148224 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0146834 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.014646 |
| PERP | PERP, TP53 apoptosis effector | -0.0146428 |
| GRB7 | growth factor receptor-bound protein 7 | -0.014521 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0144998 |
| AREG | amphiregulin | -0.014322 |
