| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.190733 |
| PLEC | plectin | 0.104483 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0969873 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0937524 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0834776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.074579 |
| FLNA | filamin A, alpha | 0.0666512 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0587324 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0576538 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0523415 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0516911 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0510668 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0459066 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0450985 |
| VCL | vinculin | 0.0436472 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0425143 |
| SPAG9 | sperm associated antigen 9 | 0.0407149 |
| MSN | moesin | 0.0406961 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.040508 |
| INTS6 | integrator complex subunit 6 | 0.0401519 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0391812 |
| VEGFA | vascular endothelial growth factor A | 0.0385704 |
| RRM2 | ribonucleotide reductase M2 | 0.0376878 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374606 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0372714 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0368792 |
| RPS4X | ribosomal protein S4, X-linked | 0.0355833 |
| USP3 | ubiquitin specific peptidase 3 | 0.0349869 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0343714 |
| TGFB1 | transforming growth factor, beta 1 | 0.0343688 |
| QKI | QKI, KH domain containing, RNA binding | 0.034274 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0331387 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0330925 |
| FAM13A | family with sequence similarity 13, member A | 0.032916 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.032884 |
| RCOR1 | REST corepressor 1 | 0.0323692 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321095 |
| ACTN1 | actinin, alpha 1 | 0.031833 |
| HELZ | helicase with zinc finger | 0.0315819 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0300681 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0300271 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0298091 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0297474 |
| RYBP | RING1 and YY1 binding protein | 0.0291057 |
| FN1 | fibronectin 1 | 0.0288236 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0279511 |
| YBX1 | Y box binding protein 1 | 0.0277952 |
| IRS2 | insulin receptor substrate 2 | 0.0277682 |
| IER3 | immediate early response 3 | 0.0270144 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0268788 |
| NUP58 | nucleoporin 58 | 0.0263891 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0253958 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0252562 |
| COPA | coatomer protein complex, subunit alpha | 0.0251768 |
| DIAPH1 | diaphanous-related formin 1 | 0.0250197 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0249405 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0249266 |
| ADM | adrenomedullin | 0.0246937 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240636 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0237981 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0237486 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0237272 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0234767 |
| FERMT2 | fermitin family member 2 | 0.0233437 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.023299 |
| FNDC3B | fibronectin type III domain containing 3B | 0.023126 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0229076 |
| CAPRIN2 | caprin family member 2 | 0.0224655 |
| ZNF292 | zinc finger protein 292 | 0.0224162 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0221088 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0220972 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0219464 |
| TPM3 | tropomyosin 3 | 0.0217843 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0217332 |
| RNF145 | ring finger protein 145 | 0.0216272 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0215406 |
| CUL3 | cullin 3 | 0.0215339 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0215159 |
| MYO1B | myosin IB | 0.0209336 |
| ATP13A3 | ATPase type 13A3 | 0.0209212 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0205715 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0205504 |
| MAP1B | microtubule-associated protein 1B | 0.0205217 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0203811 |
| SEPTIN9 | septin 9 | 0.0203023 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201924 |
| HOMER1 | homer scaffolding protein 1 | 0.0201146 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0199728 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198781 |
| NPTN | neuroplastin | 0.0196765 |
| CLIC4 | chloride intracellular channel 4 | 0.0192659 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0191062 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.019097 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0189403 |
| CORO1C | coronin, actin binding protein, 1C | 0.0181797 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0180136 |
| WDR45B | WD repeat domain 45B | 0.0179649 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0174693 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173305 |
| TFRC | transferrin receptor | 0.0172384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.28819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168183 |
| HMGA2 | high mobility group AT-hook 2 | -0.141824 |
| MT2A | metallothionein 2A | -0.115602 |
| NDRG1 | N-myc downstream regulated 1 | -0.0928625 |
| TMSB10 | thymosin beta 10 | -0.0883439 |
| CDCP1 | CUB domain containing protein 1 | -0.086716 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0842728 |
| CDH13 | cadherin 13 | -0.0804092 |
| ASPH | aspartate beta-hydroxylase | -0.0797172 |
| RAI14 | retinoic acid induced 14 | -0.071278 |
| COL5A1 | collagen, type V, alpha 1 | -0.0696304 |
| CD44 | CD44 molecule (Indian blood group) | -0.0685492 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0681554 |
| ENO1 | enolase 1, (alpha) | -0.0647751 |
| TENM2 | teneurin transmembrane protein 2 | -0.062362 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0612106 |
| IGF2 | insulin-like growth factor 2 | -0.0604931 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0569574 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0566743 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0525065 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0524449 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0517846 |
| MYO10 | myosin X | -0.0513718 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0503178 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0468119 |
| EFNA5 | ephrin-A5 | -0.0454707 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0446269 |
| NAV1 | neuron navigator 1 | -0.0445871 |
| AHNAK | AHNAK nucleoprotein | -0.0444547 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0418825 |
| COL1A1 | collagen, type I, alpha 1 | -0.0405783 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0401287 |
| RIN2 | Ras and Rab interactor 2 | -0.0400414 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.039495 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0393582 |
| FMN1 | formin 1 | -0.0377686 |
| GLIS3 | GLIS family zinc finger 3 | -0.0375706 |
| YEATS2 | YEATS domain containing 2 | -0.0369009 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0367215 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0363885 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0352562 |
| ETV6 | ets variant 6 | -0.0352164 |
| NF1 | neurofibromin 1 | -0.0350862 |
| OSMR | oncostatin M receptor | -0.0342118 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0340774 |
| CUX1 | cut-like homeobox 1 | -0.0338012 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0333121 |
| RUNX1 | runt-related transcription factor 1 | -0.0332052 |
| PCBP3 | poly(rC) binding protein 3 | -0.0330556 |
| LOX | lysyl oxidase | -0.0324277 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0322051 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0316659 |
| USP34 | ubiquitin specific peptidase 34 | -0.0313525 |
| RPL35A | ribosomal protein L35a | -0.0311921 |
| PRKCA | protein kinase C, alpha | -0.031143 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0308761 |
| ACTG1 | actin gamma 1 | -0.0307266 |
| TMEM165 | transmembrane protein 165 | -0.0305713 |
| PRSS23 | protease, serine, 23 | -0.0293039 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.029236 |
| TPM1 | tropomyosin 1 (alpha) | -0.0291809 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0287757 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.028333 |
| SMYD3 | SET and MYND domain containing 3 | -0.0281459 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0280975 |
| CAVIN1 | caveolae associated protein 1 | -0.0280532 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0279164 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0275227 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0272444 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0271209 |
| CCND1 | cyclin D1 | -0.0270688 |
| NAV2 | neuron navigator 2 | -0.026916 |
| NGLY1 | N-glycanase 1 | -0.0269067 |
| ATXN1 | ataxin 1 | -0.0267373 |
| PDE10A | phosphodiesterase 10A | -0.0264793 |
| RPS16 | ribosomal protein S16 | -0.026256 |
| CCDC91 | coiled-coil domain containing 91 | -0.0261763 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258693 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.025799 |
| SBF2 | SET binding factor 2 | -0.0257579 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0257102 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0250844 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.025003 |
| MAP4 | microtubule-associated protein 4 | -0.0249777 |
| SMAD3 | SMAD family member 3 | -0.024857 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0247543 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.024666 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0245379 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0245121 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.024498 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0242933 |
| FNIP1 | folliculin interacting protein 1 | -0.0242343 |
| CLMP | CXADR-like membrane protein | -0.0242069 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0239024 |
| TUBB | tubulin, beta class I | -0.023776 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0236183 |
| RPS19 | ribosomal protein S19 | -0.0235913 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0235371 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0234413 |
