| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.134063 |
| IGF2 | insulin-like growth factor 2 | 0.118205 |
| C3 | complement component 3 | 0.0917372 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0848825 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0834788 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0774179 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0729594 |
| TF | transferrin | 0.0722586 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0625156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0582378 |
| JMJD1C | jumonji domain containing 1C | 0.056672 |
| SVIL | supervillin | 0.0480995 |
| CP | ceruloplasmin (ferroxidase) | 0.0459742 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.045343 |
| TNS1 | tensin 1 | 0.043956 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0436801 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0426987 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0420313 |
| NDRG1 | N-myc downstream regulated 1 | 0.0415276 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0380699 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.037238 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0361778 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0361766 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0328022 |
| CRY1 | cryptochrome circadian clock 1 | 0.0324272 |
| VEGFA | vascular endothelial growth factor A | 0.0323888 |
| PEG3 | paternally expressed 3 | 0.0318235 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0305784 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0304283 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0293745 |
| FAM13A | family with sequence similarity 13, member A | 0.0292608 |
| RBM39 | RNA binding motif protein 39 | 0.0290601 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0285293 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0281198 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0276585 |
| RLF | rearranged L-myc fusion | 0.0275811 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0272971 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0267242 |
| AHSG | alpha-2-HS-glycoprotein | 0.026616 |
| RPL11 | ribosomal protein L11 | 0.0265348 |
| DSPP | dentin sialophosphoprotein | 0.026512 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0262224 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0260718 |
| FBXO42 | F-box protein 42 | 0.0252912 |
| FOXP1 | forkhead box P1 | 0.0252591 |
| RUNX1 | runt-related transcription factor 1 | 0.0250435 |
| TXNRD1 | thioredoxin reductase 1 | 0.0247311 |
| DTNA | dystrobrevin, alpha | 0.0241521 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0241429 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0235719 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0234723 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0233391 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0230772 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0217904 |
| MYO6 | myosin VI | 0.0216976 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0215924 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0212175 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0209369 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0208564 |
| RAI14 | retinoic acid induced 14 | 0.0206685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0204099 |
| NUP58 | nucleoporin 58 | 0.0200695 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0198724 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0196454 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0196126 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0195791 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0195728 |
| APOA1 | apolipoprotein A-I | 0.0193433 |
| ENO1 | enolase 1, (alpha) | 0.0192429 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0190495 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0190025 |
| INSIG2 | insulin induced gene 2 | 0.0189341 |
| KRT18 | keratin 18, type I | 0.0187777 |
| STC2 | stanniocalcin 2 | 0.0185501 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0183919 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0182338 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0181726 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.018095 |
| PER2 | period circadian clock 2 | 0.0179314 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0178148 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0178095 |
| CCNY | cyclin Y | 0.0177854 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0177273 |
| CPE | carboxypeptidase E | 0.0175545 |
| WDR45B | WD repeat domain 45B | 0.0174555 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0173747 |
| CALR | calreticulin | 0.0172801 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0172345 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0171753 |
| USP6NL | USP6 N-terminal like | 0.017144 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0171394 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0171182 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0166929 |
| NGLY1 | N-glycanase 1 | 0.0165716 |
| SLC38A1 | solute carrier family 38, member 1 | 0.016431 |
| YME1L1 | YME1-like 1 ATPase | 0.016401 |
| DIDO1 | death inducer-obliterator 1 | 0.0162748 |
| HLA-E | major histocompatibility complex, class I, E | 0.0162145 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0161716 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.016135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.0751818 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0461622 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0455481 |
| TMSB10 | thymosin beta 10 | -0.0405391 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0394809 |
| HMGA1 | high mobility group AT-hook 1 | -0.0376552 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.03429 |
| FRMD5 | FERM domain containing 5 | -0.033792 |
| VCL | vinculin | -0.0330208 |
| ITGAV | integrin, alpha V | -0.0320566 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0303165 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0298059 |
| GPC3 | glypican 3 | -0.0287659 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0284464 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0265632 |
| ACTN4 | actinin, alpha 4 | -0.0264284 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0259972 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259722 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0258182 |
| INTS6 | integrator complex subunit 6 | -0.0255471 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0249394 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0246942 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0243143 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0218184 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0215345 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0210655 |
| MALT1 | MALT1 paracaspase | -0.0206325 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0202462 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0187384 |
| HNMT | histamine N-methyltransferase | -0.0180866 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0179885 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0177638 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0173307 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0173227 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0172071 |
| HLF | hepatic leukemia factor | -0.0169612 |
| ACTN1 | actinin, alpha 1 | -0.0165323 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0165141 |
| TPM1 | tropomyosin 1 (alpha) | -0.0165034 |
| APOA2 | apolipoprotein A-II | -0.0163845 |
| RNF43 | ring finger protein 43 | -0.0163459 |
| ITGB5 | integrin, beta 5 | -0.0161795 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0161413 |
| ACTG1 | actin gamma 1 | -0.016044 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0159757 |
| RPL9 | ribosomal protein L9 | -0.0158219 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0158201 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0154115 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0147264 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0146849 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0145781 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0142911 |
| KIF21A | kinesin family member 21A | -0.0141025 |
| TXNIP | thioredoxin interacting protein | -0.0140679 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0140161 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0140131 |
| PTCHD4 | patched domain containing 4 | -0.0138796 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0138515 |
| VCAN | versican | -0.013739 |
| DST | dystonin | -0.0137227 |
| FOXN3 | forkhead box N3 | -0.0136601 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0135102 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0134941 |
| HPCAL1 | hippocalcin-like 1 | -0.0134262 |
| JAG1 | jagged 1 | -0.0133542 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0133389 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0133277 |
| ATXN1 | ataxin 1 | -0.0132799 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.0131739 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0129048 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0128152 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.012731 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0126179 |
| SP100 | SP100 nuclear antigen | -0.0125139 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0124883 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0123218 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0121773 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0121144 |
| GPC6 | glypican 6 | -0.0121088 |
| MYO1E | myosin IE | -0.0117917 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0117793 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0117456 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0117161 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0116398 |
| TOP1 | topoisomerase (DNA) I | -0.0116212 |
| CLIC1 | chloride intracellular channel 1 | -0.0116159 |
| GLRX | glutaredoxin (thioltransferase) | -0.0114992 |
| NABP1 | nucleic acid binding protein 1 | -0.0114814 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0114125 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0112966 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0112197 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0111987 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0111687 |
| EFNA5 | ephrin-A5 | -0.011127 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0111247 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0110705 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0110274 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0109836 |
| BCL2L1 | BCL2-like 1 | -0.01095 |
| EGR1 | early growth response 1 | -0.0109167 |
