Sodium Salicylate_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sodium Salicylate perturbation in J82 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sodium Salicylate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FTH1 ferritin, heavy polypeptide 1 0.107695
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0887426
INTS6 integrator complex subunit 6 0.0738022
FLNA filamin A, alpha 0.0737627
EXT1 exostosin glycosyltransferase 1 0.0586652
ERBIN erbb2 interacting protein 0.0573857
PDLIM5 PDZ and LIM domain 5 0.0436725
VCL vinculin 0.0406575
ZSWIM6 zinc finger, SWIM-type containing 6 0.0389377
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0375023
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0371046
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0363185
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0336424
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0330323
PODXL podocalyxin-like 0.032529
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.032403
BCL2L1 BCL2-like 1 0.0321104
NRIP1 nuclear receptor interacting protein 1 0.030253
SH3RF1 SH3 domain containing ring finger 1 0.0294135
ASPH aspartate beta-hydroxylase 0.027384
MYH9 myosin, heavy chain 9, non-muscle 0.0272459
TLE4 transducin-like enhancer of split 4 0.0270028
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0256772
MSN moesin 0.0251158
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.024221
COL5A1 collagen, type V, alpha 1 0.0241018
STARD13 StAR-related lipid transfer (START) domain containing 13 0.0240934
ACTN1 actinin, alpha 1 0.0227841
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0222732
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0222031
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0216402
TPM3 tropomyosin 3 0.0216262
NAV1 neuron navigator 1 0.0215418
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 0.0212974
FHIT fragile histidine triad 0.0211359
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0209763
L1CAM L1 cell adhesion molecule 0.0209287
EFNA5 ephrin-A5 0.0208708
DOCK5 dedicator of cytokinesis 5 0.0204945
SLIT2 slit homolog 2 (Drosophila) 0.020076
RAD51B RAD51 paralog B 0.0196182
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0195244
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0186597
NCOR2 nuclear receptor corepressor 2 0.0186426
CEMIP2 cell migration inducing hyaluronidase 2 0.0185887
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0185841
RIMS2 regulating synaptic membrane exocytosis 2 0.0184564
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.018387
FLNB filamin B, beta 0.0183607
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0182824
PRRC2A proline-rich coiled-coil 2A 0.018269
NABP1 nucleic acid binding protein 1 0.0181401
APLP2 amyloid beta (A4) precursor-like protein 2 0.0180642
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0180366
SEPTIN9 septin 9 0.0178967
TUFT1 tuftelin 1 0.01783
SMAD3 SMAD family member 3 0.0176334
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 0.0175383
KLF12 Kruppel-like factor 12 0.0174969
MYO1E myosin IE 0.0174623
PDE4D phosphodiesterase 4D, cAMP-specific 0.0173765
SAMD4A sterile alpha motif domain containing 4A 0.0169668
CAPZB capping protein (actin filament) muscle Z-line, beta 0.0169292
EEF2 eukaryotic translation elongation factor 2 0.0169007
MPRIP myosin phosphatase Rho interacting protein 0.0168681
PCLO piccolo presynaptic cytomatrix protein 0.0166281
DST dystonin 0.0164977
MB21D2 Mab-21 domain containing 2 0.0164388
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0164296
GLS2 glutaminase 2 (liver, mitochondrial) 0.015988
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0158304
VMP1 vacuole membrane protein 1 0.0158006
PLEC plectin 0.0155353
TSC22D2 TSC22 domain family, member 2 0.0154556
RRM2 ribonucleotide reductase M2 0.0153606
MTAP methylthioadenosine phosphorylase 0.0153424
COL7A1 collagen, type VII, alpha 1 0.0153129
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.0153022
TGM2 transglutaminase 2 0.0152988
LRMDA leucine rich melanocyte differentiation associated 0.0152863
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.0152656
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.0152419
IPO9 importin 9 0.0150536
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0147813
HEG1 heart development protein with EGF-like domains 1 0.0147007
BCAR3 breast cancer anti-estrogen resistance 3 0.0146756
VEGFC vascular endothelial growth factor C 0.0146631
WNT5B wingless-type MMTV integration site family, member 5B 0.0145971
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0145043
PRELID2 PRELI domain containing 2 0.0143265
UTRN utrophin 0.0142036
CALD1 caldesmon 1 0.0141564
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.014126
VGLL3 vestigial-like family member 3 0.0139003
FHL2 four and a half LIM domains 2 0.013747
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0137232
SFPQ splicing factor proline/glutamine-rich 0.0137131
PLSCR1 phospholipid scramblase 1 0.0136913
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.0136274
DIAPH3 diaphanous-related formin 3 0.0133777

decreased expression

Symbol Name Standardized Value
FTL ferritin, light polypeptide -0.206613
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.173592
IGFBP3 insulin-like growth factor binding protein 3 -0.16323
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.143118
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.120223
UGCG UDP-glucose ceramide glucosyltransferase -0.104472
FN1 fibronectin 1 -0.0919709
PTMA prothymosin, alpha -0.0854999
NDRG1 N-myc downstream regulated 1 -0.0847569
HLA-B major histocompatibility complex, class I, B -0.0828729
NAMPT nicotinamide phosphoribosyltransferase -0.0799361
DLG1 discs, large homolog 1 (Drosophila) -0.0785172
RPL35A ribosomal protein L35a -0.0678091
PDIA3 protein disulfide isomerase family A, member 3 -0.0654697
VIM vimentin -0.0607101
SLC12A8 solute carrier family 12, member 8 -0.0580329
MT2A metallothionein 2A -0.0579411
DEK DEK proto-oncogene -0.0572788
CALR calreticulin -0.0565932
MT1X metallothionein 1X -0.0563857
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0559945
ENO1 enolase 1, (alpha) -0.055622
RPS6 ribosomal protein S6 -0.0555601
KPNB1 karyopherin (importin) beta 1 -0.0541884
CANX calnexin -0.0506651
ABI3BP ABI family, member 3 (NESH) binding protein -0.0505461
TMSB4X thymosin beta 4, X-linked -0.0486874
PLIN2 perilipin 2 -0.0474818
TMSB10 thymosin beta 10 -0.0461484
PGK1 phosphoglycerate kinase 1 -0.0440778
ANXA2 annexin A2 -0.0431362
WSB1 WD repeat and SOCS box containing 1 -0.0411191
ATP13A3 ATPase type 13A3 -0.0406374
ANXA1 annexin A1 -0.0403656
TPT1 tumor protein, translationally-controlled 1 -0.0397489
RLF rearranged L-myc fusion -0.0388798
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0388172
TPD52 tumor protein D52 -0.0386972
JUN jun proto-oncogene -0.0385105
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0384167
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0381857
S100A6 S100 calcium binding protein A6 -0.0379752
CAVIN1 caveolae associated protein 1 -0.0379713
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0375181
RPS8 ribosomal protein S8 -0.0373482
RBM39 RNA binding motif protein 39 -0.037312
RPLP2 ribosomal protein, large, P2 -0.0372983
MARCKS myristoylated alanine-rich protein kinase C substrate -0.036797
B2M beta-2-microglobulin -0.036524
ZFR zinc finger RNA binding protein -0.0360664
RAI14 retinoic acid induced 14 -0.0358657
FAM162A family with sequence similarity 162, member A -0.0358545
RPL12 ribosomal protein L12 -0.0357895
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0351814
TUBB tubulin, beta class I -0.0350144
GOLGA4 golgin A4 -0.0349176
NPEPPS aminopeptidase puromycin sensitive -0.0346868
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0344658
RPLP1 ribosomal protein, large, P1 -0.0344072
POSTN periostin, osteoblast specific factor -0.0343109
MKI67 marker of proliferation Ki-67 -0.0342719
BZW1 basic leucine zipper and W2 domains 1 -0.0341588
ELL2 elongation factor, RNA polymerase II, 2 -0.0341226
EIF1 eukaryotic translation initiation factor 1 -0.0337955
S100A10 S100 calcium binding protein A10 -0.0337614
ARF4 ADP-ribosylation factor 4 -0.0336438
ADM adrenomedullin -0.0333912
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0324875
AHNAK AHNAK nucleoprotein -0.0324742
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0323831
GNAS GNAS complex locus -0.0322524
HMGB1 high mobility group box 1 -0.0320567
HLA-E major histocompatibility complex, class I, E -0.0317458
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0313002
NUP58 nucleoporin 58 -0.0312744
PKM pyruvate kinase, muscle -0.0309682
RAD21 RAD21 homolog (S. pombe) -0.0306917
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0306004
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0305601
ZNF292 zinc finger protein 292 -0.0304038
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -0.0300942
YEATS2 YEATS domain containing 2 -0.0300516
PHACTR1 phosphatase and actin regulator 1 -0.0300451
IL1RAP interleukin 1 receptor accessory protein -0.0293574
STK4 serine/threonine kinase 4 -0.0292434
MMP12 matrix metallopeptidase 12 -0.029183
BASP1 brain abundant, membrane attached signal protein 1 -0.0287795
MAP4 microtubule-associated protein 4 -0.0287593
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0286611
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0284871
LMAN1 lectin, mannose-binding, 1 -0.0283997
RIOK3 RIO kinase 3 -0.0283772
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0280155
MTDH metadherin -0.0275777
VDAC1 voltage-dependent anion channel 1 -0.0270114
RAB6A RAB6A, member RAS oncogene family -0.026644
USP3 ubiquitin specific peptidase 3 -0.026216
BTG1 B-cell translocation gene 1, anti-proliferative -0.026115
IFITM3 interferon induced transmembrane protein 3 -0.0260907
RPL26 ribosomal protein L26 -0.0260571