| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.124943 |
| GRB10 | growth factor receptor-bound protein 10 | 0.107231 |
| SMAD3 | SMAD family member 3 | 0.0958938 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0866127 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0856875 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0823711 |
| PCBP2 | poly(rC) binding protein 2 | 0.080415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0798267 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0678618 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0655658 |
| TGM2 | transglutaminase 2 | 0.0611867 |
| NAV2 | neuron navigator 2 | 0.0610213 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0602445 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0585051 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0554419 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.055282 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0552599 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0549535 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0522313 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0517838 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0513811 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0498871 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0492716 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0485334 |
| AADAC | arylacetamide deacetylase | 0.048303 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0474876 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0473624 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0463626 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0462289 |
| EXT1 | exostosin glycosyltransferase 1 | 0.046142 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0431203 |
| SPAG9 | sperm associated antigen 9 | 0.0429752 |
| NDRG1 | N-myc downstream regulated 1 | 0.0425532 |
| INTS6 | integrator complex subunit 6 | 0.042266 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0419631 |
| ATXN1 | ataxin 1 | 0.0418939 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0417644 |
| LOXL2 | lysyl oxidase-like 2 | 0.0415751 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0407336 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0394656 |
| PTK2 | protein tyrosine kinase 2 | 0.038623 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0386179 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0385458 |
| EFNA5 | ephrin-A5 | 0.0385415 |
| NTN4 | netrin 4 | 0.0384482 |
| RUNX1 | runt-related transcription factor 1 | 0.0370999 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0369257 |
| HELZ | helicase with zinc finger | 0.036647 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0358083 |
| SIK3 | SIK family kinase 3 | 0.0351893 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0351045 |
| RARB | retinoic acid receptor, beta | 0.0349957 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0348837 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0340776 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0337908 |
| RBM39 | RNA binding motif protein 39 | 0.0334359 |
| VEGFA | vascular endothelial growth factor A | 0.0320867 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0320783 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0318249 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0317424 |
| WLS | wntless Wnt ligand secretion mediator | 0.031037 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0308109 |
| ANXA2 | annexin A2 | 0.0307677 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.030764 |
| MED13 | mediator complex subunit 13 | 0.0307328 |
| ECE1 | endothelin converting enzyme 1 | 0.0305545 |
| ZNF638 | zinc finger protein 638 | 0.030452 |
| PKM | pyruvate kinase, muscle | 0.0302445 |
| DTNA | dystrobrevin, alpha | 0.0300451 |
| TGFB1 | transforming growth factor, beta 1 | 0.0299933 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0296849 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0296824 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0296422 |
| ADD3 | adducin 3 (gamma) | 0.0296181 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0294103 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0293338 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0289727 |
| YBX1 | Y box binding protein 1 | 0.0285282 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0284382 |
| MYO10 | myosin X | 0.0283738 |
| ASPH | aspartate beta-hydroxylase | 0.0279168 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0276516 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0275965 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.027339 |
| FAM107B | family with sequence similarity 107, member B | 0.0269845 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0261642 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0259757 |
| FAM13A | family with sequence similarity 13, member A | 0.0255242 |
| PARD3 | par-3 family cell polarity regulator | 0.0251472 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0248832 |
| RCOR1 | REST corepressor 1 | 0.02474 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0247267 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0245683 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0243537 |
| HMGA2 | high mobility group AT-hook 2 | 0.0243247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243134 |
| EZR | ezrin | 0.0240949 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.024041 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0240208 |
| FAM20C | family with sequence similarity 20, member C | 0.0238961 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.128675 |
| TMSB10 | thymosin beta 10 | -0.106577 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0586671 |
| OSMR | oncostatin M receptor | -0.0572366 |
| FN1 | fibronectin 1 | -0.0535267 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0532566 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0518906 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0503852 |
| LOX | lysyl oxidase | -0.0450576 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.038961 |
| CDH13 | cadherin 13 | -0.0383226 |
| VIM | vimentin | -0.0378796 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0378489 |
| NRG1 | neuregulin 1 | -0.0375391 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0369373 |
| ENO1 | enolase 1, (alpha) | -0.0366582 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0358227 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353976 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.034579 |
| GPC6 | glypican 6 | -0.034413 |
| SYT1 | synaptotagmin I | -0.0334631 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0321779 |
| ETV6 | ets variant 6 | -0.0311891 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0308816 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0301128 |
| EXOC4 | exocyst complex component 4 | -0.0293531 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0291831 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289851 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0286019 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0281161 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0279663 |
| S100A6 | S100 calcium binding protein A6 | -0.0278948 |
| NAV3 | neuron navigator 3 | -0.0278717 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0268105 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0267467 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0259724 |
| MYO9A | myosin IXA | -0.02501 |
| MECOM | MDS1 and EVI1 complex locus | -0.025006 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0248896 |
| CDCP1 | CUB domain containing protein 1 | -0.0248405 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0247353 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0242241 |
| ZNF804A | zinc finger protein 804A | -0.0242004 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0237276 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0236208 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0232619 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0229555 |
| RPL37A | ribosomal protein L37a | -0.0224857 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0224517 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0221732 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0218462 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0216072 |
| CLMP | CXADR-like membrane protein | -0.0211172 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0210738 |
| B2M | beta-2-microglobulin | -0.0209741 |
| RPS19 | ribosomal protein S19 | -0.0205973 |
| PGK1 | phosphoglycerate kinase 1 | -0.0205183 |
| PRSS23 | protease, serine, 23 | -0.0200865 |
| RPL36 | ribosomal protein L36 | -0.0199959 |
| DST | dystonin | -0.0199069 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.019881 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0198593 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0193186 |
| HDLBP | high density lipoprotein binding protein | -0.01899 |
| COL12A1 | collagen, type XII, alpha 1 | -0.018966 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0186752 |
| ATG7 | autophagy related 7 | -0.0185679 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0183654 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0183244 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0182047 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0181834 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0180037 |
| HLA-B | major histocompatibility complex, class I, B | -0.0179859 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0178451 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0176884 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0176649 |
| EHBP1 | EH domain binding protein 1 | -0.0176127 |
| DCN | decorin | -0.0175332 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0171916 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0171352 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0170192 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.016928 |
| ATM | ATM serine/threonine kinase | -0.0168506 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.016644 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0165475 |
| PCNX4 | pecanex 4 | -0.0161518 |
| RPL34 | ribosomal protein L34 | -0.0160672 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0160504 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0160479 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0159034 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0158389 |
| AOPEP | aminopeptidase O (putative) | -0.0158049 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0157204 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.01571 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0155923 |
| LRRC49 | leucine rich repeat containing 49 | -0.0154919 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0154546 |
| ENOSF1 | enolase superfamily member 1 | -0.0154381 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0153478 |
| RPL37 | ribosomal protein L37 | -0.0152699 |