| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.150459 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.08254 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0563905 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0425071 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0410918 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0347722 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0333148 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.029564 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0293853 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0287681 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0261081 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0241719 |
| KYNU | kynureninase | 0.0239057 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0231188 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0219003 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0215386 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0208207 |
| EGFR | epidermal growth factor receptor | 0.0200186 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0181847 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0176585 |
| FLNB | filamin B, beta | 0.0176528 |
| COPA | coatomer protein complex, subunit alpha | 0.0172259 |
| HLA-B | major histocompatibility complex, class I, B | 0.0169726 |
| FLNA | filamin A, alpha | 0.0168091 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0167685 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.016706 |
| FMNL2 | formin-like 2 | 0.0165714 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0165128 |
| PYGL | phosphorylase, glycogen, liver | 0.0164516 |
| ATXN1 | ataxin 1 | 0.0164431 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0163515 |
| CMIP | c-Maf inducing protein | 0.0160517 |
| RAD51B | RAD51 paralog B | 0.0157202 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.01562 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.01516 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0148264 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0146239 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0146195 |
| UTRN | utrophin | 0.0146125 |
| GOLGA4 | golgin A4 | 0.0145874 |
| EHBP1 | EH domain binding protein 1 | 0.0145832 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0145686 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0140563 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0136664 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.01359 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0133947 |
| MYO1E | myosin IE | 0.0132392 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0131201 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0125521 |
| NDRG1 | N-myc downstream regulated 1 | 0.0125163 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0123104 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0122177 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0118066 |
| VCL | vinculin | 0.0117855 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0114049 |
| TGM2 | transglutaminase 2 | 0.0112765 |
| USP34 | ubiquitin specific peptidase 34 | 0.0111393 |
| GOLGB1 | golgin B1 | 0.0110982 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0110251 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0110194 |
| SFTPA2 | surfactant protein A2 | 0.0109673 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0108817 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0108097 |
| KRT18 | keratin 18, type I | 0.010746 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0107371 |
| GLIS3 | GLIS family zinc finger 3 | 0.0107261 |
| DST | dystonin | 0.0106897 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0106484 |
| TPM1 | tropomyosin 1 (alpha) | 0.0105831 |
| FHIT | fragile histidine triad | 0.0105253 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0105164 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0101595 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0099531 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00972573 |
| WWOX | WW domain containing oxidoreductase | 0.00970679 |
| HLA-A | major histocompatibility complex, class I, A | 0.00968805 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00937917 |
| CALD1 | caldesmon 1 | 0.00933027 |
| INTS6 | integrator complex subunit 6 | 0.00932451 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.00931298 |
| HMGA2 | high mobility group AT-hook 2 | 0.00927936 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00927551 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.00926892 |
| NF1 | neurofibromin 1 | 0.00920926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00920157 |
| PRELID2 | PRELI domain containing 2 | 0.009135 |
| EFNA1 | ephrin-A1 | 0.0091136 |
| PRKCA | protein kinase C, alpha | 0.00908631 |
| ANGPTL4 | angiopoietin-like 4 | 0.00906708 |
| IL6 | interleukin 6 | 0.0089517 |
| MED13 | mediator complex subunit 13 | 0.00894183 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0089327 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.00886045 |
| PDE10A | phosphodiesterase 10A | 0.00884969 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00872555 |
| PATJ | PATJ crumbs cell polarity complex component | 0.00864917 |
| BRD2 | bromodomain containing 2 | 0.00860787 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00858839 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.00856629 |
| SCFD1 | sec1 family domain containing 1 | 0.00856366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0799067 |
| VIM | vimentin | -0.0780479 |
| TMSB10 | thymosin beta 10 | -0.0780341 |
| MT2A | metallothionein 2A | -0.0656215 |
| TXNRD1 | thioredoxin reductase 1 | -0.0638233 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0591146 |
| PTMA | prothymosin, alpha | -0.0525165 |
| RPL23 | ribosomal protein L23 | -0.0510272 |
| FTL | ferritin, light polypeptide | -0.0507203 |
| RPS27A | ribosomal protein S27a | -0.0475441 |
| GRAMD1B | GRAM domain containing 1B | -0.0461308 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0428754 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0374003 |
| UBC | ubiquitin C | -0.0362125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0353247 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.034079 |
| FGB | fibrinogen beta chain | -0.0324431 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.031525 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0287074 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02814 |
| RPL19 | ribosomal protein L19 | -0.0277252 |
| ENO1 | enolase 1, (alpha) | -0.0273417 |
| RPS12 | ribosomal protein S12 | -0.0255572 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0248735 |
| RPL4 | ribosomal protein L4 | -0.0247898 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0238592 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0231764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0228344 |
| PKM | pyruvate kinase, muscle | -0.0221398 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0216709 |
| RPLP1 | ribosomal protein, large, P1 | -0.0215888 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0215331 |
| ACTG1 | actin gamma 1 | -0.021419 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0201494 |
| RTN4 | reticulon 4 | -0.0200939 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0200122 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0198788 |
| S100A6 | S100 calcium binding protein A6 | -0.0192825 |
| RPL8 | ribosomal protein L8 | -0.0191911 |
| RPL36 | ribosomal protein L36 | -0.019061 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0190108 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.018452 |
| CAVIN1 | caveolae associated protein 1 | -0.0184205 |
| YBX1 | Y box binding protein 1 | -0.0182879 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.017523 |
| RPL26 | ribosomal protein L26 | -0.0171289 |
| ANLN | anillin, actin binding protein | -0.0163134 |
| PFDN2 | prefoldin subunit 2 | -0.0162826 |
| RPS29 | ribosomal protein S29 | -0.0160279 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0160108 |
| RPS8 | ribosomal protein S8 | -0.0160062 |
| RACK1 | receptor for activated C kinase 1 | -0.0159322 |
| MKI67 | marker of proliferation Ki-67 | -0.0156048 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0151172 |
| RPS3 | ribosomal protein S3 | -0.0150386 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0150168 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0148583 |
| IER3 | immediate early response 3 | -0.0146 |
| TPD52 | tumor protein D52 | -0.0144891 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0144825 |
| RPL7 | ribosomal protein L7 | -0.0144178 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0143986 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0138264 |
| RPL5 | ribosomal protein L5 | -0.013813 |
| TNPO1 | transportin 1 | -0.0137851 |
| TPM3 | tropomyosin 3 | -0.0137792 |
| ANXA2 | annexin A2 | -0.013728 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.013706 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0136027 |
| CANX | calnexin | -0.0135707 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.013499 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0134088 |
| RPS25 | ribosomal protein S25 | -0.0133319 |
| RPL30 | ribosomal protein L30 | -0.0132384 |
| RHEB | Ras homolog enriched in brain | -0.0131839 |
| RPS21 | ribosomal protein S21 | -0.0129728 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0129547 |
| RPS19 | ribosomal protein S19 | -0.0128593 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0128415 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0127008 |
| AHNAK | AHNAK nucleoprotein | -0.0126345 |
| RPS5 | ribosomal protein S5 | -0.0124325 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.012287 |
| PCBP2 | poly(rC) binding protein 2 | -0.0122722 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0122018 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0121099 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0120763 |
| KIF5B | kinesin family member 5B | -0.012044 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0120315 |
| USP3 | ubiquitin specific peptidase 3 | -0.0120309 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0119368 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0119266 |
| TMEM123 | transmembrane protein 123 | -0.0119126 |
| ANKRD28 | ankyrin repeat domain 28 | -0.011882 |
| RPL35A | ribosomal protein L35a | -0.0117124 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0115357 |
| RPL12 | ribosomal protein L12 | -0.0114365 |
| HMGB1 | high mobility group box 1 | -0.0113509 |
| WDR43 | WD repeat domain 43 | -0.0113196 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0112723 |
