| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0979807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0882488 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0700708 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0634507 |
| VMP1 | vacuole membrane protein 1 | 0.055862 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0548539 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0496168 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0491301 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0457667 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0435088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0400215 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0391505 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0382737 |
| GPC6 | glypican 6 | 0.0382193 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0371572 |
| ENO1 | enolase 1, (alpha) | 0.036839 |
| IGF2 | insulin-like growth factor 2 | 0.0362827 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0355863 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0343676 |
| EGFR | epidermal growth factor receptor | 0.0333164 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0322057 |
| EZR | ezrin | 0.0318899 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.031815 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0314845 |
| VIM | vimentin | 0.0312279 |
| MYOF | myoferlin | 0.030095 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0300525 |
| KYNU | kynureninase | 0.0298246 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0292024 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0290318 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0285515 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0284112 |
| FAM107B | family with sequence similarity 107, member B | 0.0282797 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0282452 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0274648 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0274519 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0268997 |
| RNF213 | ring finger protein 213 | 0.0263432 |
| FRMD5 | FERM domain containing 5 | 0.0261457 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0259901 |
| FOXO3 | forkhead box O3 | 0.0259576 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0259156 |
| CNKSR3 | CNKSR family member 3 | 0.0258109 |
| PLEC | plectin | 0.0256235 |
| TXNRD1 | thioredoxin reductase 1 | 0.0254864 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0252911 |
| GPHN | gephyrin | 0.0247247 |
| FOXP1 | forkhead box P1 | 0.0243458 |
| FN1 | fibronectin 1 | 0.0239876 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0238666 |
| UBC | ubiquitin C | 0.0236963 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0234477 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0227555 |
| VCL | vinculin | 0.0227191 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0226558 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.022399 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0222993 |
| FLNB | filamin B, beta | 0.0222988 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0219712 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0219467 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0218501 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0218394 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0217866 |
| QKI | QKI, KH domain containing, RNA binding | 0.0217696 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0212417 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212388 |
| POLK | polymerase (DNA directed) kappa | 0.0209526 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0209094 |
| AHNAK | AHNAK nucleoprotein | 0.0206165 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0205632 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02037 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0200134 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0198865 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0198607 |
| ABHD2 | abhydrolase domain containing 2 | 0.0198387 |
| MT2A | metallothionein 2A | 0.0198051 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0197598 |
| NF1 | neurofibromin 1 | 0.0197135 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0196778 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0196299 |
| MEIS2 | Meis homeobox 2 | 0.0196209 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0195708 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0193222 |
| RPL19 | ribosomal protein L19 | 0.0192789 |
| TCF12 | transcription factor 12 | 0.01927 |
| KRT17 | keratin 17, type I | 0.0192566 |
| H3-3B | H3.3 histone B | 0.0191923 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0189429 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0186894 |
| ACTG1 | actin gamma 1 | 0.0186347 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0186209 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0185567 |
| TJP1 | tight junction protein 1 | 0.0185309 |
| RYK | receptor-like tyrosine kinase | 0.0184964 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0181711 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0180059 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.017947 |
| MSN | moesin | 0.017929 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0177632 |
| MYO5B | myosin VB | 0.0174662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.0957574 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.05342 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0461257 |
| ATOSA | atos homolog A | -0.0456194 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0454513 |
| FTL | ferritin, light polypeptide | -0.0449248 |
| DTNA | dystrobrevin, alpha | -0.0407108 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0395098 |
| EGR1 | early growth response 1 | -0.0389035 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0375966 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0370089 |
| TLK1 | tousled-like kinase 1 | -0.0359843 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0353999 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0353012 |
| TXNIP | thioredoxin interacting protein | -0.0343494 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0338686 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0336175 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0333862 |
| LSAMP | limbic system-associated membrane protein | -0.0329992 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0328235 |
| NUP58 | nucleoporin 58 | -0.0302803 |
| HMGA2 | high mobility group AT-hook 2 | -0.0297767 |
| TMEM165 | transmembrane protein 165 | -0.029606 |
| RCOR1 | REST corepressor 1 | -0.0295123 |
| NEMF | nuclear export mediator factor | -0.0295073 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.029001 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0282197 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0279713 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0278552 |
| ZNF638 | zinc finger protein 638 | -0.0277705 |
| PKN2 | protein kinase N2 | -0.0275982 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0275845 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0275816 |
| RIOK3 | RIO kinase 3 | -0.0273725 |
| PTK2 | protein tyrosine kinase 2 | -0.0273143 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0267808 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.026591 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0265224 |
| RNF149 | ring finger protein 149 | -0.0264235 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.025791 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256564 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0249823 |
| SRPK2 | SRSF protein kinase 2 | -0.0249195 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0245809 |
| RBM47 | RNA binding motif protein 47 | -0.0244819 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0243773 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0242738 |
| SETD5 | SET domain containing 5 | -0.0241061 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0239528 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0239005 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0235457 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0233191 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.023182 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0231667 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0230263 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0229691 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0229589 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0228534 |
| RAI14 | retinoic acid induced 14 | -0.022336 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0222851 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0219544 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0217958 |
| CSTB | cystatin B (stefin B) | -0.0216867 |
| INHBA | inhibin, beta A | -0.0213945 |
| RPL35A | ribosomal protein L35a | -0.0213881 |
| RPL18 | ribosomal protein L18 | -0.0213216 |
| POTEF | POTE ankyrin domain family, member F | -0.0213089 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0211622 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0210775 |
| RBM25 | RNA binding motif protein 25 | -0.0210102 |
| S100A11 | S100 calcium binding protein A11 | -0.0209031 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0207081 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0205671 |
| HLA-B | major histocompatibility complex, class I, B | -0.0203064 |
| RORA | RAR-related orphan receptor A | -0.0202412 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0200719 |
| FRMD6 | FERM domain containing 6 | -0.0200093 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0199496 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0198423 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0197935 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0197933 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0197077 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0196178 |
| KIF16B | kinesin family member 16B | -0.0194431 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0194022 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0193447 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0192858 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0192572 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0189751 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0189665 |
| RIGI | RNA sensor RIG-I | -0.0188686 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0187842 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0187266 |
| MXD1 | MAX dimerization protein 1 | -0.0186863 |
| GLCCI1 | glucocorticoid induced 1 | -0.0186472 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0185863 |
| NBEAL1 | neurobeachin-like 1 | -0.0184403 |
| RPS17 | ribosomal protein S17 | -0.0183387 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0183214 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0182056 |
