| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.164343 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124903 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.113695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0997388 |
| MCL1 | myeloid cell leukemia 1 | 0.0892696 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0883529 |
| VCL | vinculin | 0.0858374 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0852896 |
| HMGA2 | high mobility group AT-hook 2 | 0.0652116 |
| VIM | vimentin | 0.0624099 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0596852 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0590215 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0580299 |
| AHNAK | AHNAK nucleoprotein | 0.0532681 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0531242 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0530917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0530592 |
| WWOX | WW domain containing oxidoreductase | 0.0523437 |
| PDLIM5 | PDZ and LIM domain 5 | 0.051784 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0514583 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0509382 |
| OSMR | oncostatin M receptor | 0.0507941 |
| INTS6 | integrator complex subunit 6 | 0.0505983 |
| GNAS | GNAS complex locus | 0.0491914 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0463024 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0458651 |
| PRELID2 | PRELI domain containing 2 | 0.0454074 |
| PDE10A | phosphodiesterase 10A | 0.0454043 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0445679 |
| FMNL2 | formin-like 2 | 0.0444887 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0444604 |
| TMSB10 | thymosin beta 10 | 0.0440362 |
| RNF213 | ring finger protein 213 | 0.0433841 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0430957 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0430489 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0417449 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0417096 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.041394 |
| AEBP2 | AE binding protein 2 | 0.041183 |
| ACTG1 | actin gamma 1 | 0.0401455 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.039624 |
| EXOC4 | exocyst complex component 4 | 0.0395309 |
| SMAD3 | SMAD family member 3 | 0.038679 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0385344 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0381838 |
| HOMER1 | homer scaffolding protein 1 | 0.0381292 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0368232 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0366769 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0366403 |
| VMP1 | vacuole membrane protein 1 | 0.0361785 |
| TPM2 | tropomyosin 2 (beta) | 0.0339112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0323192 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0322685 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0317252 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0315045 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0313603 |
| ATG7 | autophagy related 7 | 0.0309941 |
| RPS4X | ribosomal protein S4, X-linked | 0.0308042 |
| TPM4 | tropomyosin 4 | 0.0305056 |
| GRAMD1B | GRAM domain containing 1B | 0.0302873 |
| KRT18 | keratin 18, type I | 0.0302131 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0294435 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0290603 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0290584 |
| TRIM59 | tripartite motif containing 59 | 0.0288187 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0284576 |
| RAD51B | RAD51 paralog B | 0.0283674 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0276346 |
| RAB7A | RAB7A, member RAS oncogene family | 0.027511 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.027501 |
| ATXN1 | ataxin 1 | 0.0273421 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.027277 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0268853 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0264176 |
| DENND1A | DENN/MADD domain containing 1A | 0.0261025 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0260368 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0257515 |
| PLEC | plectin | 0.0256439 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0255443 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0247783 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.024625 |
| FLNA | filamin A, alpha | 0.0243301 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0242812 |
| RYR3 | ryanodine receptor 3 | 0.0242475 |
| DENND5B | DENN/MADD domain containing 5B | 0.0239579 |
| H1-0 | H1.0 linker histone | 0.0237344 |
| DIAPH2 | diaphanous-related formin 2 | 0.0232607 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0231023 |
| NEK10 | NIMA-related kinase 10 | 0.0229417 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0229019 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0228818 |
| TLN1 | talin 1 | 0.0228334 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.022483 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0223488 |
| TMEM131 | transmembrane protein 131 | 0.0223279 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0222828 |
| STC1 | stanniocalcin 1 | 0.0222723 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0221221 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0220018 |
| MAP7 | microtubule-associated protein 7 | 0.0219826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.227958 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.116065 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0987245 |
| RTN4 | reticulon 4 | -0.0914452 |
| TXNRD1 | thioredoxin reductase 1 | -0.086071 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0768601 |
| RPS2 | ribosomal protein S2 | -0.0698461 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0645686 |
| XPO1 | exportin 1 | -0.0567321 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0520756 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0494049 |
| RPS3 | ribosomal protein S3 | -0.0484727 |
| MKI67 | marker of proliferation Ki-67 | -0.0479105 |
| GOLGA4 | golgin A4 | -0.0474737 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.045872 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0452545 |
| PCBP2 | poly(rC) binding protein 2 | -0.0444096 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0432958 |
| RPS12 | ribosomal protein S12 | -0.0431602 |
| CLTC | clathrin, heavy chain (Hc) | -0.0407279 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0400066 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0384996 |
| RPL26 | ribosomal protein L26 | -0.0384106 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.037964 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.037941 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0379334 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0369194 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0368771 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0366529 |
| SET | SET nuclear proto-oncogene | -0.0364381 |
| TPI1 | triosephosphate isomerase 1 | -0.0363095 |
| RPL37 | ribosomal protein L37 | -0.0347936 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0347933 |
| RPL37A | ribosomal protein L37a | -0.0347181 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0342394 |
| PHIP | pleckstrin homology domain interacting protein | -0.0340054 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0339832 |
| RPL3 | ribosomal protein L3 | -0.033627 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0334832 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0332396 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0327769 |
| CENPF | centromere protein F, 350/400kDa | -0.0320549 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0319762 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0319241 |
| GPHN | gephyrin | -0.0315209 |
| RPL38 | ribosomal protein L38 | -0.0314941 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0313371 |
| PCNX1 | pecanex 1 | -0.0312419 |
| ZNF292 | zinc finger protein 292 | -0.0310159 |
| ZNF638 | zinc finger protein 638 | -0.0309655 |
| TPM3 | tropomyosin 3 | -0.0308836 |
| RASA2 | RAS p21 protein activator 2 | -0.0306298 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0306056 |
| RECQL | RecQ helicase-like | -0.030557 |
| KIF5B | kinesin family member 5B | -0.0305481 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0304525 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0302888 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0301095 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0295236 |
| RPS29 | ribosomal protein S29 | -0.029184 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0291002 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0288571 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0285527 |
| NOP58 | NOP58 ribonucleoprotein | -0.0284016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.028243 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0282264 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0279829 |
| ANO6 | anoctamin 6 | -0.0279319 |
| SRPK1 | SRSF protein kinase 1 | -0.0279031 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0278693 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.027292 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0271221 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0269633 |
| NUP153 | nucleoporin 153kDa | -0.0265459 |
| PNN | pinin, desmosome associated protein | -0.0264996 |
| RPS6 | ribosomal protein S6 | -0.0263522 |
| YBX3 | Y box binding protein 3 | -0.0263036 |
| PLCB4 | phospholipase C, beta 4 | -0.026097 |
| RPS18 | ribosomal protein S18 | -0.0259083 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0259008 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0258639 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.0258263 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0256451 |
| MED13L | mediator complex subunit 13-like | -0.025481 |
| EPN2 | epsin 2 | -0.0252061 |
| ZNF654 | zinc finger protein 654 | -0.0251949 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0251867 |
| MMP12 | matrix metallopeptidase 12 | -0.0250441 |
| TMEM165 | transmembrane protein 165 | -0.0250268 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0250075 |
| CEP192 | centrosomal protein 192kDa | -0.0248657 |
| RPS10 | ribosomal protein S10 | -0.0247519 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0246841 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0244704 |
| GOLT1B | golgi transport 1B | -0.0244369 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.024409 |
| AFF4 | AF4/FMR2 family, member 4 | -0.024281 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0241667 |
| BBX | bobby sox homolog (Drosophila) | -0.0241562 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.024135 |
