| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.171141 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.154196 |
| TXNRD1 | thioredoxin reductase 1 | 0.126373 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.122169 |
| GRAMD1B | GRAM domain containing 1B | 0.103775 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0980397 |
| GDA | guanine deaminase | 0.0965496 |
| MYOF | myoferlin | 0.0957104 |
| COL5A2 | collagen, type V, alpha 2 | 0.0927348 |
| KYNU | kynureninase | 0.0907406 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0860176 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0844323 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0815773 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0806945 |
| NRCAM | neuronal cell adhesion molecule | 0.0781396 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0754883 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0750763 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0743856 |
| NEK7 | NIMA-related kinase 7 | 0.0740591 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0720881 |
| DST | dystonin | 0.0708837 |
| CENPF | centromere protein F, 350/400kDa | 0.0631699 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.06265 |
| EFNA5 | ephrin-A5 | 0.057733 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0552576 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0551683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0538959 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0538007 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0532049 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0504667 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0491286 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0490905 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0488362 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0478662 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0473408 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0472497 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0470118 |
| MKI67 | marker of proliferation Ki-67 | 0.0466459 |
| RTN4 | reticulon 4 | 0.0463804 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0460431 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.045703 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0455155 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.044845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.043791 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0423776 |
| MFF | mitochondrial fission factor | 0.0414661 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0414174 |
| PGK1 | phosphoglycerate kinase 1 | 0.0411209 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0405087 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0394647 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0393455 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0383541 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0368486 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0363353 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0360723 |
| ENAH | enabled homolog (Drosophila) | 0.0356822 |
| OGA | O-GlcNAcase | 0.0354254 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0350375 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0348645 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0342511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0340481 |
| RPS4X | ribosomal protein S4, X-linked | 0.0340376 |
| TNPO1 | transportin 1 | 0.0339509 |
| CTSC | cathepsin C | 0.0338463 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0332532 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0331389 |
| TPR | translocated promoter region, nuclear basket protein | 0.0330264 |
| CDK6 | cyclin-dependent kinase 6 | 0.0325875 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0323212 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0317843 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0317204 |
| DIAPH3 | diaphanous-related formin 3 | 0.0316761 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0313003 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0302929 |
| SPAG9 | sperm associated antigen 9 | 0.029948 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0293754 |
| RGS2 | regulator of G-protein signaling 2 | 0.0292812 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0292187 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0289799 |
| COL4A5 | collagen, type IV, alpha 5 | 0.028277 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0282302 |
| PHF20 | PHD finger protein 20 | 0.0282273 |
| PALLD | palladin, cytoskeletal associated protein | 0.0274245 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0274013 |
| PTGR1 | prostaglandin reductase 1 | 0.0272987 |
| NF1 | neurofibromin 1 | 0.0267871 |
| PRKD3 | protein kinase D3 | 0.0266981 |
| RBM39 | RNA binding motif protein 39 | 0.0263997 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0263494 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0263202 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0260817 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0258002 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0257107 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0256469 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0256279 |
| EZR | ezrin | 0.0255663 |
| FLNB | filamin B, beta | 0.0255505 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0254337 |
| RBM25 | RNA binding motif protein 25 | 0.025364 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.025342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.238982 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.084794 |
| AUTS2 | autism susceptibility candidate 2 | -0.0832832 |
| CDH13 | cadherin 13 | -0.0763697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0652276 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0650197 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0530115 |
| FN1 | fibronectin 1 | -0.0484617 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0453279 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0384839 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0357769 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0336199 |
| NCKAP5 | NCK-associated protein 5 | -0.0336198 |
| DENND1A | DENN/MADD domain containing 1A | -0.0324448 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0304828 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.030057 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0291316 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.026418 |
| CUX1 | cut-like homeobox 1 | -0.0259311 |
| DNER | delta/notch-like EGF repeat containing | -0.0243712 |
| HDAC4 | histone deacetylase 4 | -0.0242379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0232991 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0231061 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0230176 |
| PCDH9 | protocadherin 9 | -0.0227529 |
| RAD51B | RAD51 paralog B | -0.0227132 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0224433 |
| LAMA5 | laminin, alpha 5 | -0.0217707 |
| GLRX | glutaredoxin (thioltransferase) | -0.0210305 |
| RANBP17 | RAN binding protein 17 | -0.0207305 |
| XYLT1 | xylosyltransferase I | -0.0204256 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0202426 |
| SMAD2 | SMAD family member 2 | -0.0201992 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0199557 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0199382 |
| FNIP1 | folliculin interacting protein 1 | -0.019789 |
| LSAMP | limbic system-associated membrane protein | -0.0197525 |
| PRELID2 | PRELI domain containing 2 | -0.019689 |
| PYGL | phosphorylase, glycogen, liver | -0.0195678 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0194557 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0191123 |
| NDRG1 | N-myc downstream regulated 1 | -0.0186187 |
| CADM2 | cell adhesion molecule 2 | -0.018101 |
| RPL31 | ribosomal protein L31 | -0.0179257 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.0178893 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0174437 |
| VIM | vimentin | -0.0170104 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0168455 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0165973 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0165449 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0163074 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0161609 |
| C9ORF153 | chromosome 9 open reading frame 153 | -0.0156743 |
| CTBP2 | C-terminal binding protein 2 | -0.0156546 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0149121 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0147545 |
| RPL37 | ribosomal protein L37 | -0.0146994 |
| ATP9B | ATPase, class II, type 9B | -0.0143469 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0143269 |
| TENM3 | teneurin transmembrane protein 3 | -0.0142046 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0139946 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.01381 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0136988 |
| PCDH15 | protocadherin-related 15 | -0.013694 |
| PRKCA | protein kinase C, alpha | -0.0135654 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0132977 |
| TNRC6C | trinucleotide repeat containing 6C | -0.0131766 |
| AEBP2 | AE binding protein 2 | -0.0130046 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0129978 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0128549 |
| EGR1 | early growth response 1 | -0.0128065 |
| C1D | C1D nuclear receptor corepressor | -0.0126505 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.012442 |
| RHOB | ras homolog family member B | -0.0122196 |
| KIF16B | kinesin family member 16B | -0.0120857 |
| RPS23 | ribosomal protein S23 | -0.0118802 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.011782 |
| PCBP3 | poly(rC) binding protein 3 | -0.0116407 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0116335 |
| CA12 | carbonic anhydrase XII | -0.0116053 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0115674 |
| NRXN3 | neurexin 3 | -0.0114218 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0111232 |
| RPS27 | ribosomal protein S27 | -0.011084 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0110417 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0110133 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0109665 |
| DTNA | dystrobrevin, alpha | -0.0109027 |
| GPC5 | glypican 5 | -0.0108702 |
| TMEM165 | transmembrane protein 165 | -0.0108562 |
| SMYD3 | SET and MYND domain containing 3 | -0.0108209 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0107593 |
| STEAP1B | STEAP family member 1B | -0.0106612 |
| GOLGA3 | golgin A3 | -0.0105546 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0105239 |
| RORA | RAR-related orphan receptor A | -0.0104601 |
| CLMP | CXADR-like membrane protein | -0.0103883 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0103438 |
| ZFHX3 | zinc finger homeobox 3 | -0.0103392 |
| RPS19 | ribosomal protein S19 | -0.0102494 |
