| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.152947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134873 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.124502 |
| EXT1 | exostosin glycosyltransferase 1 | 0.122883 |
| PDE10A | phosphodiesterase 10A | 0.0984941 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0956969 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0895274 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0821163 |
| PKM | pyruvate kinase, muscle | 0.0799572 |
| FTL | ferritin, light polypeptide | 0.0793941 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0775624 |
| DST | dystonin | 0.0768972 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0766573 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0750583 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0743771 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0687557 |
| RPS12 | ribosomal protein S12 | 0.0677639 |
| ERBIN | erbb2 interacting protein | 0.065025 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0633339 |
| RPL35A | ribosomal protein L35a | 0.0612795 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0601536 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0598314 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0593504 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0576494 |
| SBF2 | SET binding factor 2 | 0.0557818 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0546807 |
| PGK1 | phosphoglycerate kinase 1 | 0.0541179 |
| SCFD1 | sec1 family domain containing 1 | 0.0524545 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.051593 |
| RPS11 | ribosomal protein S11 | 0.0502593 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0497207 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0495515 |
| POTEF | POTE ankyrin domain family, member F | 0.0487978 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0485228 |
| PTK2 | protein tyrosine kinase 2 | 0.0484165 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0473037 |
| RUNX1 | runt-related transcription factor 1 | 0.0468882 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0466916 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0454508 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0454303 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0454213 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0449743 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0440909 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0430903 |
| PLEC | plectin | 0.0423042 |
| EFNA5 | ephrin-A5 | 0.0419715 |
| ASPH | aspartate beta-hydroxylase | 0.0415278 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0414715 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0411912 |
| GPC6 | glypican 6 | 0.0392587 |
| INTS6 | integrator complex subunit 6 | 0.0386266 |
| GNAS | GNAS complex locus | 0.0385529 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0373456 |
| RORA | RAR-related orphan receptor A | 0.0372252 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0368872 |
| FMN1 | formin 1 | 0.0366414 |
| TCF12 | transcription factor 12 | 0.0363916 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0360316 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0357539 |
| OGA | O-GlcNAcase | 0.0357022 |
| CDK6 | cyclin-dependent kinase 6 | 0.0351041 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0349497 |
| TXNRD1 | thioredoxin reductase 1 | 0.0345171 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0343618 |
| LDHA | lactate dehydrogenase A | 0.0340932 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0337327 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0333519 |
| ZNF292 | zinc finger protein 292 | 0.0333167 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0328584 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.03279 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0327732 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0325461 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0321919 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0320114 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0317272 |
| SPAG9 | sperm associated antigen 9 | 0.0299889 |
| VCL | vinculin | 0.0294894 |
| MED13 | mediator complex subunit 13 | 0.0290745 |
| FAM13A | family with sequence similarity 13, member A | 0.0290334 |
| RASA2 | RAS p21 protein activator 2 | 0.0273341 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.026962 |
| CTBP2 | C-terminal binding protein 2 | 0.0269215 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266223 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0255209 |
| STC1 | stanniocalcin 1 | 0.0255026 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0254587 |
| NDRG1 | N-myc downstream regulated 1 | 0.0254024 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0242047 |
| MAP1B | microtubule-associated protein 1B | 0.0237771 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.023251 |
| CANX | calnexin | 0.0231473 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0227667 |
| USP34 | ubiquitin specific peptidase 34 | 0.0227524 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0225172 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218815 |
| VMP1 | vacuole membrane protein 1 | 0.0217415 |
| CMIP | c-Maf inducing protein | 0.0209765 |
| RPL19 | ribosomal protein L19 | 0.020199 |
| TOP1 | topoisomerase (DNA) I | 0.0197899 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0196192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.156826 |
| FN1 | fibronectin 1 | -0.138825 |
| HMGA2 | high mobility group AT-hook 2 | -0.121908 |
| TMSB10 | thymosin beta 10 | -0.116882 |
| PCBP2 | poly(rC) binding protein 2 | -0.107478 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.104468 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0986589 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0921344 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0918825 |
| CD44 | CD44 molecule (Indian blood group) | -0.0914934 |
| ATP11A | ATPase, class VI, type 11A | -0.0820542 |
| RTN4 | reticulon 4 | -0.0759776 |
| EGFR | epidermal growth factor receptor | -0.0754485 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0745909 |
| MYO10 | myosin X | -0.0745036 |
| RPS27A | ribosomal protein S27a | -0.0744503 |
| VIM | vimentin | -0.0731167 |
| PTMA | prothymosin, alpha | -0.0714747 |
| ENO1 | enolase 1, (alpha) | -0.068256 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0675298 |
| RPLP1 | ribosomal protein, large, P1 | -0.0665033 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.065746 |
| OSMR | oncostatin M receptor | -0.0650326 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0575261 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0572729 |
| PRKCA | protein kinase C, alpha | -0.0569526 |
| SLTM | SAFB-like, transcription modulator | -0.0566441 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0564343 |
| COL1A1 | collagen, type I, alpha 1 | -0.0558515 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0555399 |
| B2M | beta-2-microglobulin | -0.0550662 |
| EMP1 | epithelial membrane protein 1 | -0.0539826 |
| RNF213 | ring finger protein 213 | -0.0522229 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0512836 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0511263 |
| TXNIP | thioredoxin interacting protein | -0.0509604 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0486495 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0474499 |
| NAV1 | neuron navigator 1 | -0.0472599 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0469402 |
| ITGA6 | integrin, alpha 6 | -0.0466016 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.046569 |
| MMP1 | matrix metallopeptidase 1 | -0.0461653 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0461047 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0435414 |
| RPL34 | ribosomal protein L34 | -0.0427916 |
| PDE8A | phosphodiesterase 8A | -0.0422612 |
| RBM25 | RNA binding motif protein 25 | -0.0411518 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.040282 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0400891 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0391243 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0377162 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0376434 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0371064 |
| INHBA | inhibin, beta A | -0.0365607 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0361235 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0357204 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0350137 |
| RPL23 | ribosomal protein L23 | -0.0348617 |
| UBAC2 | UBA domain containing 2 | -0.0345189 |
| NHSL1 | NHS-like 1 | -0.0335459 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0329492 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0319252 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0315014 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0311008 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.030184 |
| SMYD3 | SET and MYND domain containing 3 | -0.0298002 |
| RAD51B | RAD51 paralog B | -0.0294935 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0294755 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0292523 |
| RCOR1 | REST corepressor 1 | -0.0284106 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0282499 |
| FOXP1 | forkhead box P1 | -0.0275805 |
| RASAL2 | RAS protein activator like 2 | -0.0263368 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0261506 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0258311 |
| LAMB3 | laminin, beta 3 | -0.0256058 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0255943 |
| ANXA2 | annexin A2 | -0.025587 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.025186 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0250905 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0247875 |
| MCL1 | myeloid cell leukemia 1 | -0.0246956 |
| SIK3 | SIK family kinase 3 | -0.0238897 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0235683 |
| GOLGB1 | golgin B1 | -0.0228955 |
| RPS6 | ribosomal protein S6 | -0.0227824 |
| LAMA4 | laminin, alpha 4 | -0.0224936 |
| TJP1 | tight junction protein 1 | -0.0224789 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0224287 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0219481 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0218079 |
| MT2A | metallothionein 2A | -0.0217613 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0217152 |
| RPL31 | ribosomal protein L31 | -0.0215309 |
| CCND1 | cyclin D1 | -0.0210391 |
| RSF1 | remodeling and spacing factor 1 | -0.0193488 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0188432 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0187582 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0183129 |