| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0505904 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0477817 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0430923 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0412354 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0378392 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0343527 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0330951 |
| UTRN | utrophin | 0.0329767 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0329694 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0326366 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0320778 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0302201 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0295846 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.028326 |
| SRPK2 | SRSF protein kinase 2 | 0.0281984 |
| QKI | QKI, KH domain containing, RNA binding | 0.0272591 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.025606 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0254485 |
| CDC73 | cell division cycle 73 | 0.0250127 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0247077 |
| SHROOM3 | shroom family member 3 | 0.0246651 |
| FBXO11 | F-box protein 11 | 0.024317 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0242068 |
| DST | dystonin | 0.0239019 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0232175 |
| MED13L | mediator complex subunit 13-like | 0.0227963 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.022113 |
| ECT2 | epithelial cell transforming 2 | 0.0220087 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0213564 |
| GOLGA4 | golgin A4 | 0.020878 |
| TMEM64 | transmembrane protein 64 | 0.0205854 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0205689 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0205407 |
| ZNF217 | zinc finger protein 217 | 0.0204687 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0204287 |
| CDC14A | cell division cycle 14A | 0.0202941 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0201037 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0199798 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0197202 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.019674 |
| FMNL2 | formin-like 2 | 0.0195302 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0193867 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0191084 |
| ZNF292 | zinc finger protein 292 | 0.0190475 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0190277 |
| CPA6 | carboxypeptidase A6 | 0.018957 |
| INTS6 | integrator complex subunit 6 | 0.0187271 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0185055 |
| SFTPA2 | surfactant protein A2 | 0.0179816 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.017976 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0178491 |
| HMGA2 | high mobility group AT-hook 2 | 0.0178436 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0177456 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0176705 |
| SPAG9 | sperm associated antigen 9 | 0.0173249 |
| KIAA1328 | KIAA1328 | 0.0171795 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0170928 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0170395 |
| FNBP1L | formin binding protein 1-like | 0.0166859 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0165006 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0164625 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.016363 |
| PARD3 | par-3 family cell polarity regulator | 0.0163404 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0161984 |
| ZNF608 | zinc finger protein 608 | 0.0161248 |
| NUP98 | nucleoporin 98kDa | 0.0161097 |
| ZNF385D | zinc finger protein 385D | 0.0160469 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0160383 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0160155 |
| PRKD1 | protein kinase D1 | 0.0160112 |
| FLNB | filamin B, beta | 0.0160084 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0159326 |
| MYO9A | myosin IXA | 0.0158412 |
| TMEM135 | transmembrane protein 135 | 0.0157208 |
| MSI2 | musashi RNA-binding protein 2 | 0.0156969 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.015514 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0154816 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0154088 |
| RREB1 | ras responsive element binding protein 1 | 0.0151514 |
| SGMS1 | sphingomyelin synthase 1 | 0.0150713 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0150348 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0150072 |
| VCL | vinculin | 0.014969 |
| RLF | rearranged L-myc fusion | 0.014958 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0149226 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0148655 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0147176 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0147042 |
| MEMO1 | mediator of cell motility 1 | 0.0146671 |
| CTNNBL1 | catenin, beta like 1 | 0.0146456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0145755 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0145662 |
| EVI5 | ecotropic viral integration site 5 | 0.0145173 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0144966 |
| JAZF1 | JAZF zinc finger 1 | 0.0144901 |
| TPD52 | tumor protein D52 | 0.0144717 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0143057 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0142977 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0142323 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0141447 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.184474 |
| COL11A1 | collagen, type XI, alpha 1 | -0.164916 |
| TMSB10 | thymosin beta 10 | -0.134017 |
| PHIP | pleckstrin homology domain interacting protein | -0.0921429 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.07408 |
| ITGAV | integrin, alpha V | -0.0699214 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0678084 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0595249 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0578641 |
| PGK1 | phosphoglycerate kinase 1 | -0.0557958 |
| POTEF | POTE ankyrin domain family, member F | -0.0557886 |
| COL5A2 | collagen, type V, alpha 2 | -0.0532816 |
| ACTG1 | actin gamma 1 | -0.0519556 |
| PCDH9 | protocadherin 9 | -0.0513114 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0504805 |
| PTMA | prothymosin, alpha | -0.0502403 |
| UBC | ubiquitin C | -0.0488943 |
| GPC3 | glypican 3 | -0.046585 |
| RPS16 | ribosomal protein S16 | -0.0464539 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0451334 |
| RPL5 | ribosomal protein L5 | -0.0446591 |
| ENO1 | enolase 1, (alpha) | -0.0441183 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0400824 |
| CADM2 | cell adhesion molecule 2 | -0.0399124 |
| RPS27A | ribosomal protein S27a | -0.0396412 |
| CALR | calreticulin | -0.0394125 |
| RPL35A | ribosomal protein L35a | -0.0389465 |
| RPS8 | ribosomal protein S8 | -0.038871 |
| RPS6 | ribosomal protein S6 | -0.038296 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0379057 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0378924 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0376706 |
| RPL23 | ribosomal protein L23 | -0.0363697 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.034917 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.033613 |
| B2M | beta-2-microglobulin | -0.0318932 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318792 |
| XPO1 | exportin 1 | -0.0317294 |
| UPP1 | uridine phosphorylase 1 | -0.031617 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313589 |
| HDAC9 | histone deacetylase 9 | -0.031244 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0299943 |
| APOE | apolipoprotein E | -0.0297905 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0296594 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.029332 |
| GSE1 | Gse1 coiled-coil protein | -0.0293289 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0290316 |
| S100A10 | S100 calcium binding protein A10 | -0.0289895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0289848 |
| RBM25 | RNA binding motif protein 25 | -0.0289547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0289063 |
| RPL11 | ribosomal protein L11 | -0.0286951 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0283761 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0281567 |
| COL1A2 | collagen, type I, alpha 2 | -0.0279544 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0271979 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0268155 |
| RPS3 | ribosomal protein S3 | -0.0267019 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.026316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262897 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0258807 |
| TXNRD1 | thioredoxin reductase 1 | -0.0256047 |
| RPS25 | ribosomal protein S25 | -0.0253403 |
| RPLP0 | ribosomal protein, large, P0 | -0.0252822 |
| DMD | dystrophin | -0.0250761 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.024939 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0248739 |
| FOXP2 | forkhead box P2 | -0.0241113 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0238912 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0238625 |
| MEIS2 | Meis homeobox 2 | -0.0236073 |
| RPS21 | ribosomal protein S21 | -0.0235647 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0235232 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0232781 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.0231299 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0231279 |
| RAI1 | retinoic acid induced 1 | -0.0231145 |
| RPS12 | ribosomal protein S12 | -0.0230785 |
| RPL36 | ribosomal protein L36 | -0.0230538 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0227377 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0223726 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0223273 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0222815 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.022272 |
| RPL18 | ribosomal protein L18 | -0.0222701 |
| PCBP2 | poly(rC) binding protein 2 | -0.0220977 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0220204 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0220154 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0219906 |
| PLS3 | plastin 3 | -0.0217707 |
| PFN1 | profilin 1 | -0.0217608 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0216389 |
| TUBA1B | tubulin, alpha 1b | -0.0215517 |
| SBF2 | SET binding factor 2 | -0.0214347 |
| ATXN2 | ataxin 2 | -0.0212269 |
| PDGFC | platelet derived growth factor C | -0.0210667 |
| CBX3 | chromobox homolog 3 | -0.0210082 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0207539 |
| SFPQ | splicing factor proline/glutamine-rich | -0.020673 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0205543 |