Sodium Salicylate_PANC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sodium Salicylate perturbation in PANC-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sodium Salicylate_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.125745
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0779479
MYH9 myosin, heavy chain 9, non-muscle 0.0724377
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0656771
ZCCHC7 zinc finger, CCHC domain containing 7 0.0594541
FBL fibrillarin 0.0582021
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0566572
APLP2 amyloid beta (A4) precursor-like protein 2 0.0560767
YBX1 Y box binding protein 1 0.0552207
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0529208
SPAG9 sperm associated antigen 9 0.0503998
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0468351
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0458538
SMAD3 SMAD family member 3 0.0453248
PDIA3 protein disulfide isomerase family A, member 3 0.0444266
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0422236
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0421191
GOLGA4 golgin A4 0.041742
ZFP36 ZFP36 ring finger protein 0.0417033
FNDC3B fibronectin type III domain containing 3B 0.0411009
SEPTIN9 septin 9 0.040403
LOC112694756 uncharaterized LOC112694756 0.0403759
KTN1 kinectin 1 (kinesin receptor) 0.0402231
TRIO trio Rho guanine nucleotide exchange factor 0.0399045
PLEC plectin 0.039842
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0389476
FMNL2 formin-like 2 0.038936
EEF2 eukaryotic translation elongation factor 2 0.0384074
CANX calnexin 0.0364917
FTH1 ferritin, heavy polypeptide 1 0.0344871
CALR calreticulin 0.0336815
OGA O-GlcNAcase 0.0325612
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0311588
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0309943
FXR1 fragile X mental retardation, autosomal homolog 1 0.0307333
TXNRD1 thioredoxin reductase 1 0.0304889
KDM2A lysine (K)-specific demethylase 2A 0.0303573
BIRC6 baculoviral IAP repeat containing 6 0.0301365
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0296716
PCBP2 poly(rC) binding protein 2 0.0295941
USP3 ubiquitin specific peptidase 3 0.0292812
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0289577
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0286531
SUCO SUN domain containing ossification factor 0.0286093
PDIA6 protein disulfide isomerase family A, member 6 0.0285044
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0280494
MATR3 matrin 3 0.0276859
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.027683
ARRDC3 arrestin domain containing 3 0.0272269
CTBP2 C-terminal binding protein 2 0.0271827
SFTPA2 surfactant protein A2 0.0269698
SNX14 sorting nexin 14 0.0265049
XPO1 exportin 1 0.0263572
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0262221
SRP54 signal recognition particle 54kDa 0.0261796
PKM pyruvate kinase, muscle 0.0259872
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0259265
DDIT4 DNA-damage-inducible transcript 4 0.0258041
BRD2 bromodomain containing 2 0.0256537
HYOU1 hypoxia up-regulated 1 0.0256146
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0255397
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0253197
NOP58 NOP58 ribonucleoprotein 0.0252351
TSC22D2 TSC22 domain family, member 2 0.024955
ADM adrenomedullin 0.0248455
COL18A1 collagen, type XVIII, alpha 1 0.0247494
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0247019
MORF4L2 mortality factor 4 like 2 0.024597
ZNF292 zinc finger protein 292 0.0245666
RLF rearranged L-myc fusion 0.024463
ADAM17 ADAM metallopeptidase domain 17 0.0244235
COPB1 coatomer protein complex, subunit beta 1 0.0244014
UBE2O ubiquitin-conjugating enzyme E2O 0.0238297
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0234833
SQSTM1 sequestosome 1 0.0234756
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0234147
UBA2 ubiquitin-like modifier activating enzyme 2 0.0227734
KMT2E lysine (K)-specific methyltransferase 2E 0.022742
TRA2A transformer 2 alpha homolog (Drosophila) 0.02259
FLNB filamin B, beta 0.0225865
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.0223566
RNF145 ring finger protein 145 0.0222906
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0222716
TFG TRK-fused gene 0.0222661
COPA coatomer protein complex, subunit alpha 0.0221585
WDR43 WD repeat domain 43 0.0221521
ESYT2 extended synaptotagmin-like protein 2 0.0221299
CCNL1 cyclin L1 0.0220761
TPD52 tumor protein D52 0.0219421
HELZ helicase with zinc finger 0.0215371
SETD5 SET domain containing 5 0.0214903
YAP1 Yes-associated protein 1 0.0214847
KDM5B lysine (K)-specific demethylase 5B 0.0214769
CKAP5 cytoskeleton associated protein 5 0.0213806
SEC24A SEC24 family member A 0.0212873
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0212119
NAP1L4 nucleosome assembly protein 1-like 4 0.0211917
ANXA2 annexin A2 0.0209798
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0209767
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.0207799

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.247344
VCL vinculin -0.1485
RPS16 ribosomal protein S16 -0.101724
TM4SF1 transmembrane 4 L six family member 1 -0.0974964
TMSB10 thymosin beta 10 -0.0911032
AKAP12 A kinase (PRKA) anchor protein 12 -0.0871817
RPL35A ribosomal protein L35a -0.0667834
SLC35F3 solute carrier family 35, member F3 -0.0641257
EGR1 early growth response 1 -0.0631078
THSD4 thrombospondin, type I, domain containing 4 -0.0611556
CD44 CD44 molecule (Indian blood group) -0.0608187
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0584347
RPS24 ribosomal protein S24 -0.0583173
ACTG1 actin gamma 1 -0.0532691
PTMA prothymosin, alpha -0.0506968
TPT1 tumor protein, translationally-controlled 1 -0.0459547
CARD18 caspase recruitment domain family, member 18 -0.0456592
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0436778
RPLP2 ribosomal protein, large, P2 -0.0423382
RTN4 reticulon 4 -0.0391974
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0390161
HMGA2 high mobility group AT-hook 2 -0.0385231
MT2A metallothionein 2A -0.036457
EGFR epidermal growth factor receptor -0.0360455
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -0.0352625
ZNF780B zinc finger protein 780B -0.034918
EXT1 exostosin glycosyltransferase 1 -0.0341872
SLC38A2 solute carrier family 38, member 2 -0.0336707
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0334051
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0316908
BMAL2 basic helix-loop-helix ARNT like 2 -0.0313139
OSMR oncostatin M receptor -0.0305914
RASAL2 RAS protein activator like 2 -0.0305102
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.02998
ATG7 autophagy related 7 -0.0291025
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.02881
RPS3 ribosomal protein S3 -0.0287417
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0285425
RPS13 ribosomal protein S13 -0.0275699
RPL36A ribosomal protein L36a -0.0272988
RPS21 ribosomal protein S21 -0.0266686
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0265903
FHL2 four and a half LIM domains 2 -0.0263146
NPAS2 neuronal PAS domain protein 2 -0.0262622
MCL1 myeloid cell leukemia 1 -0.0262083
RPS27A ribosomal protein S27a -0.0259425
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0258187
ASPH aspartate beta-hydroxylase -0.0257136
RPL34 ribosomal protein L34 -0.0256835
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0256641
PRSS23 protease, serine, 23 -0.0254575
EHBP1 EH domain binding protein 1 -0.0254189
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0252808
RPL37A ribosomal protein L37a -0.025213
ZBTB20 zinc finger and BTB domain containing 20 -0.0250592
WWTR1 WW domain containing transcription regulator 1 -0.0248671
CD59 CD59 molecule, complement regulatory protein -0.0244287
PHF14 PHD finger protein 14 -0.0243632
EIF3K eukaryotic translation initiation factor 3, subunit K -0.0237877
CTSD cathepsin D -0.0236755
NT5E 5'-nucleotidase, ecto (CD73) -0.0232455
MYL12B myosin, light chain 12B, regulatory -0.0231723
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0231004
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0229769
RPS8 ribosomal protein S8 -0.022955
RPL38 ribosomal protein L38 -0.0226176
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.022584
RPL37 ribosomal protein L37 -0.022012
RPL31 ribosomal protein L31 -0.0216584
RPL26 ribosomal protein L26 -0.0213943
MSRB3 methionine sulfoxide reductase B3 -0.0205086
ANGPTL4 angiopoietin-like 4 -0.0203649
RPL12 ribosomal protein L12 -0.0202177
ODF2L outer dense fiber of sperm tails 2-like -0.0199107
RPLP1 ribosomal protein, large, P1 -0.0197431
ANKRD12 ankyrin repeat domain 12 -0.0195191
UBASH3B ubiquitin associated and SH3 domain containing B -0.019165
MAP1B microtubule-associated protein 1B -0.019078
SDK1 sidekick cell adhesion molecule 1 -0.0189922
CAVIN1 caveolae associated protein 1 -0.0189209
KPNB1 karyopherin (importin) beta 1 -0.0189122
ITGB5 integrin, beta 5 -0.0189082
EID2 EP300 interacting inhibitor of differentiation 2 -0.0188895
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0188496
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0185018
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0184912
RABGAP1L RAB GTPase activating protein 1-like -0.0183086
SMYD3 SET and MYND domain containing 3 -0.0181903
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0181603
RPL9 ribosomal protein L9 -0.0181566
TPM1 tropomyosin 1 (alpha) -0.0179503
RAD51B RAD51 paralog B -0.0179062
CELF1 CUGBP, Elav-like family member 1 -0.0177716
ARHGAP29 Rho GTPase activating protein 29 -0.0177105
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0176735
EFNA5 ephrin-A5 -0.0173485
ZMYND8 zinc finger, MYND-type containing 8 -0.0169445
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0169304
DIAPH2 diaphanous-related formin 2 -0.0169109
NCEH1 neutral cholesterol ester hydrolase 1 -0.0168046