Sodium Salicylate_Panc 03.27 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sodium Salicylate perturbation in Panc 03.27 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sodium Salicylate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
INTS6 integrator complex subunit 6 0.128256
SQSTM1 sequestosome 1 0.0989355
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0845465
ZSWIM6 zinc finger, SWIM-type containing 6 0.0767342
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0639253
RPL31 ribosomal protein L31 0.0616883
FTL ferritin, light polypeptide 0.0596865
RPS8 ribosomal protein S8 0.0591089
TPT1 tumor protein, translationally-controlled 1 0.055036
BRD2 bromodomain containing 2 0.0512239
APLP2 amyloid beta (A4) precursor-like protein 2 0.0507326
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0506919
ACTG1 actin gamma 1 0.0503101
VEGFA vascular endothelial growth factor A 0.0496011
RPL35A ribosomal protein L35a 0.0491909
SMAD3 SMAD family member 3 0.0480235
RPS6 ribosomal protein S6 0.0470749
TGM2 transglutaminase 2 0.0468652
RPS29 ribosomal protein S29 0.0458851
GOLGB1 golgin B1 0.0431732
RPL37A ribosomal protein L37a 0.0431317
TJP1 tight junction protein 1 0.0426853
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0426385
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0426304
WNK1 WNK lysine deficient protein kinase 1 0.041816
EIF1 eukaryotic translation initiation factor 1 0.041693
C3 complement component 3 0.0415443
LMO7 LIM domain 7 0.0397149
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0394157
TPM4 tropomyosin 4 0.0392816
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0391465
RAB7A RAB7A, member RAS oncogene family 0.0387709
EEF2 eukaryotic translation elongation factor 2 0.0383577
NAV2 neuron navigator 2 0.0377356
SEPTIN9 septin 9 0.0370454
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0369813
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0365186
RPS10 ribosomal protein S10 0.0350535
TIMP2 TIMP metallopeptidase inhibitor 2 0.0350095
RPS23 ribosomal protein S23 0.0347051
RPS13 ribosomal protein S13 0.0336004
FLNA filamin A, alpha 0.0331284
PLEC plectin 0.0330702
FMNL2 formin-like 2 0.0329497
ABHD3 abhydrolase domain containing 3 0.0325045
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0322569
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0321425
HLA-A major histocompatibility complex, class I, A 0.0315522
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0314183
RPL7A ribosomal protein L7a 0.0313241
NDRG1 N-myc downstream regulated 1 0.0306565
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0305986
POTEF POTE ankyrin domain family, member F 0.0305168
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0304199
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0303977
RPS17 ribosomal protein S17 0.0293886
RPS25 ribosomal protein S25 0.029291
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0290928
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.02909
CTBP2 C-terminal binding protein 2 0.0288907
RIMKLB ribosomal modification protein rimK-like family member B 0.0288867
SHB Src homology 2 domain containing adaptor protein B 0.0283058
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0281578
SPTBN1 spectrin, beta, non-erythrocytic 1 0.028073
SAMD4A sterile alpha motif domain containing 4A 0.0279852
RPL13A ribosomal protein L13a 0.0278035
MACF1 microtubule-actin crosslinking factor 1 0.0278009
RPS27A ribosomal protein S27a 0.0277717
BRD4 bromodomain containing 4 0.0271938
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0271742
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0268744
SVIL supervillin 0.0261727
FAM107B family with sequence similarity 107, member B 0.0259809
RPL37 ribosomal protein L37 0.0259434
N4BP2L2 NEDD4 binding protein 2-like 2 0.0255579
JUP junction plakoglobin 0.0253454
KTN1 kinectin 1 (kinesin receptor) 0.0253415
RPS12 ribosomal protein S12 0.0252783
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0250831
PTMA prothymosin, alpha 0.024994
LOC102724023 ES1 protein homolog, mitochondrial 0.0248442
RPL23 ribosomal protein L23 0.0247895
HDAC9 histone deacetylase 9 0.0245466
MYH9 myosin, heavy chain 9, non-muscle 0.0241074
FBXO11 F-box protein 11 0.0240707
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0239619
KDM2A lysine (K)-specific demethylase 2A 0.0238221
EFNB2 ephrin-B2 0.0235424
PSEN1 presenilin 1 0.023377
UBAP2 ubiquitin associated protein 2 0.0233744
LRRC23 leucine rich repeat containing 23 0.0233229
EIF4A2 eukaryotic translation initiation factor 4A2 0.0233022
ATXN1 ataxin 1 0.0232941
FN1 fibronectin 1 0.023234
BPTF bromodomain PHD finger transcription factor 0.0230995
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0228131
RPL28 ribosomal protein L28 0.0226512
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0225781
ZNF638 zinc finger protein 638 0.0224984
EGFR epidermal growth factor receptor 0.0224402

decreased expression

Symbol Name Standardized Value
LAMA4 laminin, alpha 4 -0.0884148
TMSB4X thymosin beta 4, X-linked -0.0711749
NPEPPS aminopeptidase puromycin sensitive -0.0694368
LY6E lymphocyte antigen 6 complex, locus E -0.0635472
DSG2 desmoglein 2 -0.0619072
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0540094
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0472746
TMSB10 thymosin beta 10 -0.0455497
KRT19 keratin 19, type I -0.0442632
OSMR oncostatin M receptor -0.0442272
CD2AP CD2-associated protein -0.0440638
TMEM123 transmembrane protein 123 -0.0432122
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0406591
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0402614
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0381112
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0377789
PLAT plasminogen activator, tissue -0.0361753
S100A6 S100 calcium binding protein A6 -0.0357222
PGK1 phosphoglycerate kinase 1 -0.0325731
H1-0 H1.0 linker histone -0.0323143
PTBP3 polypyrimidine tract binding protein 3 -0.0314579
DLG1 discs, large homolog 1 (Drosophila) -0.0308361
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0300791
IFI27 interferon, alpha-inducible protein 27 -0.0300016
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0290307
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.0286227
LAMC2 laminin, gamma 2 -0.0281399
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0279223
JMJD1C jumonji domain containing 1C -0.0268898
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -0.0265326
FAM3C family with sequence similarity 3, member C -0.0262522
MYL12B myosin, light chain 12B, regulatory -0.0257749
AHNAK AHNAK nucleoprotein -0.0254381
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0251227
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0250044
CBX3 chromobox homolog 3 -0.0249642
TM4SF1 transmembrane 4 L six family member 1 -0.0249548
MT1X metallothionein 1X -0.0245817
ANLN anillin, actin binding protein -0.0245507
RPS21 ribosomal protein S21 -0.0241406
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0237854
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0229648
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0227266
NAMPT nicotinamide phosphoribosyltransferase -0.0225041
TXNIP thioredoxin interacting protein -0.0223752
B2M beta-2-microglobulin -0.0222633
F3 coagulation factor III (thromboplastin, tissue factor) -0.0220169
ITGA6 integrin, alpha 6 -0.0210958
MT2A metallothionein 2A -0.0210186
RAD21 RAD21 homolog (S. pombe) -0.0209026
EPCAM epithelial cell adhesion molecule -0.0207519
FCHSD2 FCH and double SH3 domains 2 -0.0207297
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0202959
HMGB2 high mobility group box 2 -0.0200119
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0198739
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0192272
DPYD dihydropyrimidine dehydrogenase -0.0190854
YBX3 Y box binding protein 3 -0.0188717
FRMD5 FERM domain containing 5 -0.0188519
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0186772
CDCP1 CUB domain containing protein 1 -0.0184948
RAB1A RAB1A, member RAS oncogene family -0.0181321
ZNF148 zinc finger protein 148 -0.0179993
BMAL2 basic helix-loop-helix ARNT like 2 -0.0177366
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0176615
MKI67 marker of proliferation Ki-67 -0.0176085
TUBB tubulin, beta class I -0.0170691
S100A9 S100 calcium binding protein A9 -0.0170522
KDM3A lysine (K)-specific demethylase 3A -0.0167069
TPI1 triosephosphate isomerase 1 -0.016692
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.0164269
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0160316
EFNA5 ephrin-A5 -0.016007
EMP1 epithelial membrane protein 1 -0.0156351
OSBPL3 oxysterol binding protein-like 3 -0.0156121
TXNRD1 thioredoxin reductase 1 -0.0156105
XPO1 exportin 1 -0.0155971
LDHA lactate dehydrogenase A -0.015426
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -0.0153119
RTN4 reticulon 4 -0.0152172
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0150423
ASPH aspartate beta-hydroxylase -0.014908
BST2 bone marrow stromal cell antigen 2 -0.0148797
INHBA inhibin, beta A -0.0148141
RPL23A ribosomal protein L23a -0.0147884
BZW1 basic leucine zipper and W2 domains 1 -0.0145438
RRBP1 ribosome binding protein 1 -0.0144588
RPL18 ribosomal protein L18 -0.0144563
KLF6 Kruppel-like factor 6 -0.0143901
CANX calnexin -0.0141657
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0141558
MARCHF6 membrane associated ring-CH-type finger 6 -0.0140234
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0138231
IFI16 interferon, gamma-inducible protein 16 -0.0137472
CD59 CD59 molecule, complement regulatory protein -0.0137382
RPL32 ribosomal protein L32 -0.0136812
SOCS5 suppressor of cytokine signaling 5 -0.0136413
EHBP1 EH domain binding protein 1 -0.0135646
KRT8 keratin 8, type II -0.013535
SNX4 sorting nexin 4 -0.0135303