| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.169403 |
| MCL1 | myeloid cell leukemia 1 | 0.150232 |
| PDE10A | phosphodiesterase 10A | 0.126242 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.107027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106772 |
| INHBA | inhibin, beta A | 0.0862992 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0790545 |
| STC1 | stanniocalcin 1 | 0.0776848 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0737341 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0710199 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0627477 |
| CPE | carboxypeptidase E | 0.0578436 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.056691 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0555191 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0514661 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0506343 |
| NDRG1 | N-myc downstream regulated 1 | 0.050278 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0497248 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0493493 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0486624 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0459877 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0457265 |
| CHGB | chromogranin B | 0.0450165 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0449488 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0441427 |
| ZFHX3 | zinc finger homeobox 3 | 0.0439459 |
| MAP1B | microtubule-associated protein 1B | 0.0432789 |
| VEGFA | vascular endothelial growth factor A | 0.0432032 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0429968 |
| ENO1 | enolase 1, (alpha) | 0.0426768 |
| MATR3 | matrin 3 | 0.0426724 |
| EGR1 | early growth response 1 | 0.0421931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421413 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0415521 |
| HOMER1 | homer scaffolding protein 1 | 0.0397643 |
| ASPH | aspartate beta-hydroxylase | 0.0385958 |
| TOP1 | topoisomerase (DNA) I | 0.0384695 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0379022 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0370332 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.036785 |
| SIK3 | SIK family kinase 3 | 0.0358405 |
| ACTG1 | actin gamma 1 | 0.0353037 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0351188 |
| POTEF | POTE ankyrin domain family, member F | 0.0349898 |
| FAM13A | family with sequence similarity 13, member A | 0.0347367 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0342151 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0342049 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0338835 |
| PKM | pyruvate kinase, muscle | 0.0338152 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0335373 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0332019 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0327905 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0326575 |
| NBEA | neurobeachin | 0.0324452 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0321898 |
| PCM1 | pericentriolar material 1 | 0.0320908 |
| ATF6 | activating transcription factor 6 | 0.0315114 |
| SETD5 | SET domain containing 5 | 0.0315062 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0314453 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.031343 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0311498 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0305313 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.030291 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0302841 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0301892 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0300783 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0293286 |
| AHR | aryl hydrocarbon receptor | 0.0283803 |
| SIK2 | salt-inducible kinase 2 | 0.028092 |
| TPM4 | tropomyosin 4 | 0.027924 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0279179 |
| GOLGB1 | golgin B1 | 0.0277015 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0276903 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272386 |
| SEPTIN9 | septin 9 | 0.0271514 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0271438 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0268182 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0267736 |
| SETX | senataxin | 0.0265534 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0263129 |
| CLTC | clathrin, heavy chain (Hc) | 0.0262495 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0259278 |
| EZR | ezrin | 0.0257648 |
| TSPYL2 | TSPY-like 2 | 0.0256395 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0255869 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0254966 |
| CNKSR3 | CNKSR family member 3 | 0.0253659 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0252227 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251066 |
| SEPTIN7 | septin 7 | 0.0247826 |
| CUL3 | cullin 3 | 0.0247047 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0247014 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0246086 |
| EP400 | E1A binding protein p400 | 0.0244772 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.024374 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0243513 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242005 |
| FBXO11 | F-box protein 11 | 0.0237996 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0237215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0236088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC5 | glypican 5 | -0.0694939 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0590203 |
| SNTG1 | syntrophin, gamma 1 | -0.0568939 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0548116 |
| NRG1 | neuregulin 1 | -0.0546559 |
| MT2A | metallothionein 2A | -0.0523465 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0484544 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0477941 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0411111 |
| TENM1 | teneurin transmembrane protein 1 | -0.0400963 |
| NCKAP5 | NCK-associated protein 5 | -0.0391878 |
| RPS21 | ribosomal protein S21 | -0.0387891 |
| SMYD3 | SET and MYND domain containing 3 | -0.0363615 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0358713 |
| SYT1 | synaptotagmin I | -0.0351892 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0348293 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0309808 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0290437 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.028745 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277936 |
| EXOC4 | exocyst complex component 4 | -0.0276912 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0275377 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0267621 |
| KIAA0825 | KIAA0825 | -0.0261896 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0258188 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0251971 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0250728 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0249186 |
| NLGN1 | neuroligin 1 | -0.0249043 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0248253 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0243805 |
| RNF213 | ring finger protein 213 | -0.0241679 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.024099 |
| ZNF804A | zinc finger protein 804A | -0.0239266 |
| CADM1 | cell adhesion molecule 1 | -0.0237367 |
| RIGI | RNA sensor RIG-I | -0.0234655 |
| PCDH9 | protocadherin 9 | -0.0234297 |
| RPL26 | ribosomal protein L26 | -0.0232627 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0228484 |
| PTCHD4 | patched domain containing 4 | -0.0227921 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0213291 |
| RPS3 | ribosomal protein S3 | -0.0212677 |
| RIT2 | Ras-like without CAAX 2 | -0.0212392 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0209762 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.020716 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0206781 |
| POU6F2 | POU class 6 homeobox 2 | -0.0200936 |
| PDCD10 | programmed cell death 10 | -0.0199853 |
| MMP26 | matrix metallopeptidase 26 | -0.019895 |
| FTL | ferritin, light polypeptide | -0.0197788 |
| TMSB10 | thymosin beta 10 | -0.0196276 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0195046 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0194676 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0192442 |
| RPL36AL | ribosomal protein L36a-like | -0.0188272 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.018766 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0187069 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0185864 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0184862 |
| GNAS | GNAS complex locus | -0.0184059 |
| RALYL | RALY RNA binding protein-like | -0.018314 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0181504 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0180673 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0174246 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0172294 |
| EML6 | echinoderm microtubule associated protein like 6 | -0.0171672 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0166954 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0166578 |
| RPS12 | ribosomal protein S12 | -0.0163047 |
| RPL19 | ribosomal protein L19 | -0.0162279 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0161795 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.016048 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.0159761 |
| S100A6 | S100 calcium binding protein A6 | -0.015857 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0157969 |
| CALCA | calcitonin-related polypeptide alpha | -0.0157048 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | -0.0156257 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.015324 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.015166 |
| RAD51B | RAD51 paralog B | -0.0150563 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.0149834 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0147018 |
| EPN2 | epsin 2 | -0.0146306 |
| RPL37 | ribosomal protein L37 | -0.0145421 |
| WWOX | WW domain containing oxidoreductase | -0.0145219 |
| MT1X | metallothionein 1X | -0.0142552 |
| CDK12 | cyclin-dependent kinase 12 | -0.0142381 |
| PHF21A | PHD finger protein 21A | -0.0140954 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0140904 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0140397 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0138789 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 | -0.013704 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.013624 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0134975 |
| STX16 | syntaxin 16 | -0.013462 |
| SON | SON DNA binding protein | -0.0134523 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.013416 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0132901 |
| POU2F1 | POU class 2 homeobox 1 | -0.013248 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.013191 |
