| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sodium Salicylate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.165795 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.128711 |
| FN1 | fibronectin 1 | 0.120927 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.105287 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.096632 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0839475 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0762199 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0688268 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0686365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0683168 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.065833 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0645768 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0645289 |
| CANX | calnexin | 0.0644645 |
| ZNF292 | zinc finger protein 292 | 0.0614697 |
| PGK1 | phosphoglycerate kinase 1 | 0.0603593 |
| NDRG1 | N-myc downstream regulated 1 | 0.0602004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0599372 |
| OGA | O-GlcNAcase | 0.0578342 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.056601 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0556047 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0553722 |
| SFTPA2 | surfactant protein A2 | 0.0544548 |
| HELZ | helicase with zinc finger | 0.054131 |
| CADM1 | cell adhesion molecule 1 | 0.0516844 |
| SPAG9 | sperm associated antigen 9 | 0.0485734 |
| NAV2 | neuron navigator 2 | 0.0471694 |
| SQSTM1 | sequestosome 1 | 0.0467699 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0461765 |
| FMNL2 | formin-like 2 | 0.0455113 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0452323 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0447761 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0428525 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0407006 |
| PDE10A | phosphodiesterase 10A | 0.0397988 |
| GOLGA4 | golgin A4 | 0.0389888 |
| IER3 | immediate early response 3 | 0.0387665 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0377776 |
| FLNA | filamin A, alpha | 0.0376057 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0373183 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.037276 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360698 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0357218 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0352694 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0347202 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0338976 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0337824 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0337694 |
| RAB1A | RAB1A, member RAS oncogene family | 0.032988 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0329177 |
| OPTN | optineurin | 0.0328507 |
| PRELID2 | PRELI domain containing 2 | 0.0325268 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0324084 |
| VEGFA | vascular endothelial growth factor A | 0.0323974 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0322193 |
| RND3 | Rho family GTPase 3 | 0.0322016 |
| FOXO3 | forkhead box O3 | 0.0318075 |
| MYOF | myoferlin | 0.0313997 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.031395 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0309109 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0308122 |
| RLF | rearranged L-myc fusion | 0.0307554 |
| ANXA2 | annexin A2 | 0.030667 |
| DST | dystonin | 0.0306061 |
| TKT | transketolase | 0.0304577 |
| PHF21A | PHD finger protein 21A | 0.0304128 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0301213 |
| AHNAK | AHNAK nucleoprotein | 0.0298766 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0298427 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0298023 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0297652 |
| MATR3 | matrin 3 | 0.0295471 |
| STAG2 | stromal antigen 2 | 0.0293875 |
| ASPH | aspartate beta-hydroxylase | 0.0291509 |
| USP37 | ubiquitin specific peptidase 37 | 0.0290136 |
| FNIP1 | folliculin interacting protein 1 | 0.02871 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0283221 |
| COL5A1 | collagen, type V, alpha 1 | 0.0280432 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0280336 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.028021 |
| RYBP | RING1 and YY1 binding protein | 0.027697 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0275182 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0274605 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0273756 |
| CDH13 | cadherin 13 | 0.0272618 |
| FLNB | filamin B, beta | 0.027203 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0271235 |
| HDLBP | high density lipoprotein binding protein | 0.026983 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0269402 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268947 |
| HLA-E | major histocompatibility complex, class I, E | 0.0265252 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0264781 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0263904 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0262359 |
| CALR | calreticulin | 0.0262291 |
| CEP250 | centrosomal protein 250kDa | 0.0262237 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0261976 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.025994 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0259626 |
| APP | amyloid beta (A4) precursor protein | 0.025919 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.116191 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0992362 |
| FRMD4A | FERM domain containing 4A | -0.0810135 |
| BICC1 | BicC family RNA binding protein 1 | -0.0697486 |
| GLIS3 | GLIS family zinc finger 3 | -0.0684146 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0638592 |
| CD44 | CD44 molecule (Indian blood group) | -0.061825 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0506533 |
| TMSB10 | thymosin beta 10 | -0.0478432 |
| EGR1 | early growth response 1 | -0.0470639 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0449803 |
| KYNU | kynureninase | -0.0434145 |
| NABP1 | nucleic acid binding protein 1 | -0.0391899 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0374318 |
| PALLD | palladin, cytoskeletal associated protein | -0.0361482 |
| OSMR | oncostatin M receptor | -0.0357222 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0341395 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0334064 |
| MT2A | metallothionein 2A | -0.0328231 |
| RIGI | RNA sensor RIG-I | -0.0319289 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0286234 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0284179 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0276739 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0270544 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0256265 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0255297 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0251542 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0239224 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0228838 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0215656 |
| MKI67 | marker of proliferation Ki-67 | -0.0207962 |
| PMP22 | peripheral myelin protein 22 | -0.0205293 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0203996 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0200629 |
| CLIC4 | chloride intracellular channel 4 | -0.0195092 |
| IL6 | interleukin 6 | -0.0187686 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0185639 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0184567 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0184493 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0183752 |
| NTN4 | netrin 4 | -0.0179674 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0175597 |
| RTN4 | reticulon 4 | -0.0172044 |
| EHBP1 | EH domain binding protein 1 | -0.0170286 |
| MAP1B | microtubule-associated protein 1B | -0.0168471 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0168305 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0164082 |
| S100A9 | S100 calcium binding protein A9 | -0.0163848 |
| CALD1 | caldesmon 1 | -0.0163387 |
| KLHL5 | kelch-like family member 5 | -0.0161478 |
| CENPF | centromere protein F, 350/400kDa | -0.0159362 |
| HDAC8 | histone deacetylase 8 | -0.0159122 |
| RPL9 | ribosomal protein L9 | -0.015898 |
| HLA-A | major histocompatibility complex, class I, A | -0.0158721 |
| HLA-B | major histocompatibility complex, class I, B | -0.0152963 |
| MIDN | midnolin | -0.0151373 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0151051 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0150754 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0150516 |
| CDK17 | cyclin-dependent kinase 17 | -0.0149365 |
| SYAP1 | synapse associated protein 1 | -0.0148574 |
| NAV1 | neuron navigator 1 | -0.0147598 |
| VIM | vimentin | -0.0147344 |
| NRP1 | neuropilin 1 | -0.0147061 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0146782 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0146534 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0144566 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0141913 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0138731 |
| JAK2 | Janus kinase 2 | -0.0136048 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0135443 |
| PLSCR1 | phospholipid scramblase 1 | -0.0135443 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0135276 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0134881 |
| TUT7 | terminal uridylyl transferase 7 | -0.013426 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0134002 |
| TNNC1 | troponin C type 1 (slow) | -0.0131729 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0131265 |
| STK17A | serine/threonine kinase 17a | -0.012992 |
| FAM120B | family with sequence similarity 120B | -0.0129325 |
| CPM | carboxypeptidase M | -0.0128732 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0127553 |
| TRIM22 | tripartite motif containing 22 | -0.0127528 |
| SMAD2 | SMAD family member 2 | -0.012673 |
| PLPP3 | phospholipid phosphatase 3 | -0.012656 |
| FAM3C | family with sequence similarity 3, member C | -0.0126439 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0125653 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0124193 |
| MX2 | MX dynamin-like GTPase 2 | -0.0123853 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0122646 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0121881 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0121821 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0121399 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0121172 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0120586 |
| HMGA2 | high mobility group AT-hook 2 | -0.0120292 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0119867 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0119697 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0119691 |
| KRT19 | keratin 19, type I | -0.0117992 |
