| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.151926 |
| EZR | ezrin | 0.0821554 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0617705 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0567944 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0563871 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0530484 |
| CDK13 | cyclin-dependent kinase 13 | 0.0522329 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0519153 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0493611 |
| HM13 | histocompatibility (minor) 13 | 0.0484756 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0481346 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0480623 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0468219 |
| RPS6 | ribosomal protein S6 | 0.0462962 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0457511 |
| RBM39 | RNA binding motif protein 39 | 0.0431194 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0427244 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0425508 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0395387 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0394645 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389472 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0382885 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0380328 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0370661 |
| FBXO11 | F-box protein 11 | 0.0370546 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0366841 |
| HLA-A | major histocompatibility complex, class I, A | 0.0362207 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0353554 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0350861 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0348741 |
| NDRG1 | N-myc downstream regulated 1 | 0.034537 |
| TMF1 | TATA element modulatory factor 1 | 0.0344371 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0341848 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0340345 |
| RHEB | Ras homolog enriched in brain | 0.034007 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0338678 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0332184 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.033086 |
| PTMA | prothymosin, alpha | 0.0327431 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0326807 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0326187 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0321855 |
| SIK3 | SIK family kinase 3 | 0.0319002 |
| GOLGA4 | golgin A4 | 0.0313429 |
| PTK2 | protein tyrosine kinase 2 | 0.031284 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0284045 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0282729 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0281957 |
| DIDO1 | death inducer-obliterator 1 | 0.0281801 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0281147 |
| TMEM39A | transmembrane protein 39A | 0.0278592 |
| ZNF292 | zinc finger protein 292 | 0.0277873 |
| KRT18 | keratin 18, type I | 0.0277817 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0277421 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276865 |
| SQSTM1 | sequestosome 1 | 0.027662 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0276481 |
| MYO1E | myosin IE | 0.0270473 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0270436 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0267841 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0267062 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0265351 |
| RPL37A | ribosomal protein L37a | 0.0265228 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0264869 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0262334 |
| FUS | FUS RNA binding protein | 0.0261694 |
| RPS27A | ribosomal protein S27a | 0.0258093 |
| SET | SET nuclear proto-oncogene | 0.0257147 |
| RPS13 | ribosomal protein S13 | 0.0255208 |
| TUFT1 | tuftelin 1 | 0.025417 |
| H2AC6 | H2A clustered histone 6 | 0.025191 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0249932 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0247785 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0246981 |
| HBP1 | HMG-box transcription factor 1 | 0.0246262 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0242042 |
| TJP1 | tight junction protein 1 | 0.0241119 |
| GNAS | GNAS complex locus | 0.0240668 |
| CTBP2 | C-terminal binding protein 2 | 0.0238198 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.023813 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0235949 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0235922 |
| FAM107B | family with sequence similarity 107, member B | 0.0235765 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0235477 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0234702 |
| TOP1 | topoisomerase (DNA) I | 0.0233915 |
| HDGF | hepatoma-derived growth factor | 0.0231886 |
| SPAG9 | sperm associated antigen 9 | 0.0231642 |
| RPL35A | ribosomal protein L35a | 0.0231507 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0229668 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0227794 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0225207 |
| GPHN | gephyrin | 0.0224535 |
| RBM33 | RNA binding motif protein 33 | 0.0222768 |
| MATR3 | matrin 3 | 0.0222053 |
| RPL13A | ribosomal protein L13a | 0.0220561 |
| BRD2 | bromodomain containing 2 | 0.021943 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.021933 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.021825 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0217666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.109243 |
| TMSB10 | thymosin beta 10 | -0.0904927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736041 |
| H1-0 | H1.0 linker histone | -0.0650519 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0529561 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0526747 |
| MKI67 | marker of proliferation Ki-67 | -0.0524442 |
| CENPF | centromere protein F, 350/400kDa | -0.0522645 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.051635 |
| FRMD5 | FERM domain containing 5 | -0.0485143 |
| CBX3 | chromobox homolog 3 | -0.0477499 |
| RPS21 | ribosomal protein S21 | -0.0455247 |
| B2M | beta-2-microglobulin | -0.0453645 |
| TPX2 | TPX2, microtubule-associated | -0.0436726 |
| RPL18 | ribosomal protein L18 | -0.0429206 |
| RPL12 | ribosomal protein L12 | -0.0413199 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0408552 |
| TMEM123 | transmembrane protein 123 | -0.0387456 |
| RPS19 | ribosomal protein S19 | -0.0362394 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0344699 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0335568 |
| CST3 | cystatin C | -0.0332641 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0331387 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326957 |
| PRELID2 | PRELI domain containing 2 | -0.0322992 |
| XPO1 | exportin 1 | -0.0313055 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0306444 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0303172 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0299458 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0298181 |
| SMYD3 | SET and MYND domain containing 3 | -0.0297251 |
| AHNAK | AHNAK nucleoprotein | -0.029325 |
| MYOF | myoferlin | -0.0290907 |
| RPL32 | ribosomal protein L32 | -0.0285983 |
| FAM3C | family with sequence similarity 3, member C | -0.0283131 |
| SEPTIN7 | septin 7 | -0.0280371 |
| RPL23 | ribosomal protein L23 | -0.0272772 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0268901 |
| FAT1 | FAT atypical cadherin 1 | -0.0267481 |
| S100A10 | S100 calcium binding protein A10 | -0.0265696 |
| RPL8 | ribosomal protein L8 | -0.0263033 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0258644 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0256672 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0254515 |
| RPLP2 | ribosomal protein, large, P2 | -0.0243387 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0236629 |
| SON | SON DNA binding protein | -0.0228227 |
| DSPP | dentin sialophosphoprotein | -0.0213472 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0211914 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0211069 |
| FTL | ferritin, light polypeptide | -0.0208755 |
| TXNIP | thioredoxin interacting protein | -0.0205572 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0203201 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0201581 |
| RPS5 | ribosomal protein S5 | -0.0197186 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0194748 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0194507 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0192131 |
| RPL28 | ribosomal protein L28 | -0.0190551 |
| NHSL1 | NHS-like 1 | -0.0189752 |
| KIF4A | kinesin family member 4A | -0.0187522 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0187195 |
| CDCP1 | CUB domain containing protein 1 | -0.01862 |
| DSG2 | desmoglein 2 | -0.0183582 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.0183343 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.018161 |
| GPX4 | glutathione peroxidase 4 | -0.0181136 |
| ENO1 | enolase 1, (alpha) | -0.0180721 |
| RPLP0 | ribosomal protein, large, P0 | -0.0179767 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | -0.0178319 |
| ANLN | anillin, actin binding protein | -0.0177831 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.017557 |
| WWOX | WW domain containing oxidoreductase | -0.0174228 |
| KIF11 | kinesin family member 11 | -0.0173985 |
| SEM1 | SEM1 26S proteasome subunit | -0.017383 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0173466 |
| CXXC5 | CXXC finger protein 5 | -0.0173203 |
| EPCAM | epithelial cell adhesion molecule | -0.0172026 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0171327 |
| RPL19 | ribosomal protein L19 | -0.01709 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0170883 |
| HMGB2 | high mobility group box 2 | -0.0170084 |
| ROMO1 | reactive oxygen species modulator 1 | -0.0169965 |
| PFN1 | profilin 1 | -0.0169501 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0169134 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0168745 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0168648 |
| KLF6 | Kruppel-like factor 6 | -0.0168115 |
| FOSL1 | FOS-like antigen 1 | -0.0165908 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.016516 |
| DST | dystonin | -0.0164693 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0164105 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0163844 |
| ECT2 | epithelial cell transforming 2 | -0.0161558 |
| ITGA6 | integrin, alpha 6 | -0.0160657 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0160484 |
| CCNI | cyclin I | -0.0159045 |
| PTMS | parathymosin | -0.0158973 |
| HOXB9 | homeobox B9 | -0.0158048 |
| CTTN | cortactin | -0.0157882 |