Sodium Salicylate_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sodium Salicylate perturbation in SW480 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sodium Salicylate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.167141
VCL vinculin 0.102329
INTS6 integrator complex subunit 6 0.100313
NAV2 neuron navigator 2 0.07619
CDH13 cadherin 13 0.0698701
ASPH aspartate beta-hydroxylase 0.0686166
SDK1 sidekick cell adhesion molecule 1 0.0641071
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0640402
ANO1 anoctamin 1, calcium activated chloride channel 0.0510113
CCND1 cyclin D1 0.0463066
RAD51B RAD51 paralog B 0.0385001
ADGRL2 adhesion G protein-coupled receptor L2 0.0373393
BACE2 beta-site APP-cleaving enzyme 2 0.0373092
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0358044
NPAS2 neuronal PAS domain protein 2 0.0349018
WWOX WW domain containing oxidoreductase 0.0347336
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0338685
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.032909
PDLIM5 PDZ and LIM domain 5 0.0322022
MRPS6 mitochondrial ribosomal protein S6 0.0313745
UBAP2 ubiquitin associated protein 2 0.0310576
CDK6 cyclin-dependent kinase 6 0.0282808
EZR ezrin 0.0267559
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 0.0259333
EXOC4 exocyst complex component 4 0.0249684
LRMDA leucine rich melanocyte differentiation associated 0.0248351
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0247465
CD44 CD44 molecule (Indian blood group) 0.0244129
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0241199
ZSWIM6 zinc finger, SWIM-type containing 6 0.0238039
MYO1E myosin IE 0.0234769
FTH1 ferritin, heavy polypeptide 1 0.0233608
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0228745
TAS2R14 taste receptor, type 2, member 14 0.0227863
HDAC4 histone deacetylase 4 0.0224153
LPP LIM domain containing preferred translocation partner in lipoma 0.0224047
SLC38A2 solute carrier family 38, member 2 0.0215049
ANXA3 annexin A3 0.0211829
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0210703
FHIT fragile histidine triad 0.0210546
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0210432
SERINC5 serine incorporator 5 0.0210152
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0206852
NCEH1 neutral cholesterol ester hydrolase 1 0.0204867
PCDH9 protocadherin 9 0.0199811
SKAP1 src kinase associated phosphoprotein 1 0.0199228
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.019765
FRMD5 FERM domain containing 5 0.0196188
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.0191398
SQSTM1 sequestosome 1 0.0187777
KAT6B K(lysine) acetyltransferase 6B 0.0186276
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0186118
GMDS GDP-mannose 4,6-dehydratase 0.0184712
SMAD3 SMAD family member 3 0.01819
CLSTN2 calsyntenin 2 0.0181634
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0178666
MAML2 mastermind-like 2 (Drosophila) 0.0177367
KRT18 keratin 18, type I 0.0176048
RCOR1 REST corepressor 1 0.0175928
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0174529
EGFR epidermal growth factor receptor 0.0172539
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0171469
NABP1 nucleic acid binding protein 1 0.0171192
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0165941
CSMD3 CUB and Sushi multiple domains 3 0.0165868
NTSR1 neurotensin receptor 1 (high affinity) 0.01648
FLNA filamin A, alpha 0.0164566
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0163968
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0163374
SAMD4A sterile alpha motif domain containing 4A 0.0162687
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0162686
MTAP methylthioadenosine phosphorylase 0.016242
MYOF myoferlin 0.015864
CDK13 cyclin-dependent kinase 13 0.0158361
TIMP2 TIMP metallopeptidase inhibitor 2 0.0156007
ZBTB38 zinc finger and BTB domain containing 38 0.0155974
HSPA8 heat shock 70kDa protein 8 0.0154993
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.0154674
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0153327
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0152409
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0151941
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.0151179
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.015093
RCC1 regulator of chromosome condensation 1 0.0149728
LMCD1 LIM and cysteine-rich domains 1 0.0149586
ACTN1 actinin, alpha 1 0.0147283
TIAM2 T-cell lymphoma invasion and metastasis 2 0.0147107
EHBP1 EH domain binding protein 1 0.0146877
TGFB1 transforming growth factor, beta 1 0.0145893
PRH1 proline-rich protein HaeIII subfamily 1 0.0145554
ZBTB20 zinc finger and BTB domain containing 20 0.0145524
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.0144494
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0144264
ITGB4 integrin, beta 4 0.0143881
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.0143057
BICD1 bicaudal D homolog 1 (Drosophila) 0.0142823
PCNX4 pecanex 4 0.0141896
PTPRK protein tyrosine phosphatase, receptor type, K 0.014173
PLEC plectin 0.0140162
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.0137424

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.173588
RPS6 ribosomal protein S6 -0.0908102
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0771337
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0687643
TMSB10 thymosin beta 10 -0.0656085
RPL35A ribosomal protein L35a -0.0648374
PGK1 phosphoglycerate kinase 1 -0.0559697
OXR1 oxidation resistance 1 -0.0505551
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0488821
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0484756
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0481726
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0457459
GARS1 glycyl-tRNA synthetase 1 -0.0443785
ESYT2 extended synaptotagmin-like protein 2 -0.0438947
MORF4L2 mortality factor 4 like 2 -0.0436239
RPLP1 ribosomal protein, large, P1 -0.043623
RBM39 RNA binding motif protein 39 -0.0435716
DIAPH3 diaphanous-related formin 3 -0.0434106
ZNF292 zinc finger protein 292 -0.0431471
RPL23 ribosomal protein L23 -0.042513
RPS19 ribosomal protein S19 -0.0425109
GOLGA4 golgin A4 -0.0420685
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0413397
PTMA prothymosin, alpha -0.0413346
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0410518
MKI67 marker of proliferation Ki-67 -0.0408112
ANLN anillin, actin binding protein -0.0400583
OGA O-GlcNAcase -0.0399977
RPL12 ribosomal protein L12 -0.0390989
CD46 CD46 molecule, complement regulatory protein -0.037892
RPS3 ribosomal protein S3 -0.037661
RPLP2 ribosomal protein, large, P2 -0.0373823
ENO1 enolase 1, (alpha) -0.0368664
TXNIP thioredoxin interacting protein -0.0366624
EIF1 eukaryotic translation initiation factor 1 -0.0360938
RPLP0 ribosomal protein, large, P0 -0.0351663
SMC4 structural maintenance of chromosomes 4 -0.0347388
KDM3A lysine (K)-specific demethylase 3A -0.0341489
RUNX1 runt-related transcription factor 1 -0.0340138
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0338685
NF1 neurofibromin 1 -0.0333659
AOPEP aminopeptidase O (putative) -0.0333253
BIRC6 baculoviral IAP repeat containing 6 -0.0329863
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0327536
RPL19 ribosomal protein L19 -0.0325884
RPL26 ribosomal protein L26 -0.0325006
PROX1 prospero homeobox 1 -0.0323711
VIM vimentin -0.0323176
THOC2 THO complex 2 -0.0322382
TPI1 triosephosphate isomerase 1 -0.0318689
RAD21 RAD21 homolog (S. pombe) -0.0318408
H1-0 H1.0 linker histone -0.03184
MATR3 matrin 3 -0.0316537
PRRC2C proline-rich coiled-coil 2C -0.0314769
RPL32 ribosomal protein L32 -0.0313618
KRT8 keratin 8, type II -0.0313483
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0312205
WDFY2 WD repeat and FYVE domain containing 2 -0.0306843
ABHD2 abhydrolase domain containing 2 -0.0306167
RPL11 ribosomal protein L11 -0.0305566
XPO1 exportin 1 -0.0303635
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0302469
ETNK1 ethanolamine kinase 1 -0.0302459
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -0.0302194
USP3 ubiquitin specific peptidase 3 -0.0300513
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.029892
NIPBL Nipped-B homolog (Drosophila) -0.0297422
RPS21 ribosomal protein S21 -0.0295996
BRWD3 bromodomain and WD repeat domain containing 3 -0.0295698
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0295407
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0291281
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0285337
ZFR zinc finger RNA binding protein -0.0285104
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0284992
MIS18BP1 MIS18 binding protein 1 -0.0284508
AVL9 AVL9 homolog (S. cerevisiase) -0.0283282
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0281253
SNX9 sorting nexin 9 -0.0280933
RPL5 ribosomal protein L5 -0.0280789
CENPF centromere protein F, 350/400kDa -0.0280207
FYN FYN proto-oncogene, Src family tyrosine kinase -0.0280141
RPL36A ribosomal protein L36a -0.0279944
CEMIP2 cell migration inducing hyaluronidase 2 -0.0278926
RPS8 ribosomal protein S8 -0.0278855
KPNB1 karyopherin (importin) beta 1 -0.0277314
KMT2C lysine (K)-specific methyltransferase 2C -0.0274171
NIPSNAP2 nipsnap homolog 2 -0.027207
SCAF11 SR-related CTD-associated factor 11 -0.0267807
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0266531
GLG1 golgi glycoprotein 1 -0.0263219
AKAP9 A kinase (PRKA) anchor protein 9 -0.0262287
PDE8A phosphodiesterase 8A -0.0261606
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0260551
RPS24 ribosomal protein S24 -0.025862
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0257333
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0256827
JMJD1C jumonji domain containing 1C -0.0256543
DLG1 discs, large homolog 1 (Drosophila) -0.0254512
CCDC82 coiled-coil domain containing 82 -0.0253656
RPL34 ribosomal protein L34 -0.0250387