| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sodium Salicylate perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sodium Salicylate_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.103301 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0536769 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0500786 |
| FLNA | filamin A, alpha | 0.046951 |
| SMAD3 | SMAD family member 3 | 0.0433577 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0408788 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0388454 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0342228 |
| DST | dystonin | 0.0314177 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0309729 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0305847 |
| MSN | moesin | 0.0303038 |
| VEGFC | vascular endothelial growth factor C | 0.0298929 |
| VEGFA | vascular endothelial growth factor A | 0.0267196 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0263364 |
| INTS6 | integrator complex subunit 6 | 0.0254899 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0251689 |
| PLEC | plectin | 0.0244128 |
| VCL | vinculin | 0.0238919 |
| DSPP | dentin sialophosphoprotein | 0.0236733 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0226622 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0226315 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0226263 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0224233 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0189974 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0188647 |
| TNS1 | tensin 1 | 0.0178605 |
| SEPTIN9 | septin 9 | 0.0168552 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0166333 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0166134 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0165383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0164984 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0159951 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0159239 |
| TGM2 | transglutaminase 2 | 0.0158034 |
| MED13L | mediator complex subunit 13-like | 0.0157744 |
| VMP1 | vacuole membrane protein 1 | 0.0157051 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0152254 |
| ACTN4 | actinin, alpha 4 | 0.0151795 |
| SEPTIN11 | septin 11 | 0.0151076 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0148189 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0144095 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0142822 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0140129 |
| LMO7 | LIM domain 7 | 0.0139636 |
| CENPF | centromere protein F, 350/400kDa | 0.0139458 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0137616 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0137032 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0133187 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0132779 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.0131498 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0128259 |
| FRMD4A | FERM domain containing 4A | 0.0127556 |
| MYOF | myoferlin | 0.0126004 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0125739 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0124041 |
| HDAC9 | histone deacetylase 9 | 0.0123619 |
| SON | SON DNA binding protein | 0.0121484 |
| POTEF | POTE ankyrin domain family, member F | 0.0120462 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0119502 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0119399 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0119052 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0118755 |
| TXNIP | thioredoxin interacting protein | 0.0118749 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0118628 |
| MSI2 | musashi RNA-binding protein 2 | 0.0116813 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0116287 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0115819 |
| COL5A3 | collagen, type V, alpha 3 | 0.0114433 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0114228 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0114138 |
| YAP1 | Yes-associated protein 1 | 0.0113816 |
| BRD2 | bromodomain containing 2 | 0.0113556 |
| PCM1 | pericentriolar material 1 | 0.0113021 |
| CCNY | cyclin Y | 0.0112663 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0112425 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.011193 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0111365 |
| FAT1 | FAT atypical cadherin 1 | 0.0110202 |
| TMEM39A | transmembrane protein 39A | 0.0110065 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.011006 |
| NOTCH2 | notch 2 | 0.0108661 |
| UTRN | utrophin | 0.0108118 |
| RNF213 | ring finger protein 213 | 0.0108001 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0107782 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0107759 |
| MAP1B | microtubule-associated protein 1B | 0.0107508 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0106403 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0106383 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0104875 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0103577 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0102795 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0102711 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0102011 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0101814 |
| ERBIN | erbb2 interacting protein | 0.0101568 |
| STOM | stomatin | 0.0101024 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.010072 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0100674 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.010045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21945 |
| VIM | vimentin | -0.21805 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.146252 |
| INHBA | inhibin, beta A | -0.145344 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.137458 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.132447 |
| FN1 | fibronectin 1 | -0.123562 |
| MMP1 | matrix metallopeptidase 1 | -0.110566 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109873 |
| TMSB10 | thymosin beta 10 | -0.101192 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0953331 |
| HLA-B | major histocompatibility complex, class I, B | -0.0946724 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0936374 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0849816 |
| RPS6 | ribosomal protein S6 | -0.0816781 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0785207 |
| OXR1 | oxidation resistance 1 | -0.0759308 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0757715 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0741483 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0736541 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0674007 |
| MYO10 | myosin X | -0.0671944 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0657531 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0651227 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0644723 |
| COL1A1 | collagen, type I, alpha 1 | -0.0638332 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0632097 |
| B2M | beta-2-microglobulin | -0.0598297 |
| RPL34 | ribosomal protein L34 | -0.0587183 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0585911 |
| MT2A | metallothionein 2A | -0.0577793 |
| STC1 | stanniocalcin 1 | -0.0575171 |
| CAVIN1 | caveolae associated protein 1 | -0.0556373 |
| RPLP1 | ribosomal protein, large, P1 | -0.0539562 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053676 |
| HMGA2 | high mobility group AT-hook 2 | -0.0520676 |
| FTL | ferritin, light polypeptide | -0.0510896 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0484763 |
| ATP13A3 | ATPase type 13A3 | -0.0461392 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0457101 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0453489 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0444274 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.04405 |
| RPL35A | ribosomal protein L35a | -0.0431113 |
| MMP12 | matrix metallopeptidase 12 | -0.0429338 |
| TPM4 | tropomyosin 4 | -0.0425313 |
| HLA-A | major histocompatibility complex, class I, A | -0.0422063 |
| ACTG1 | actin gamma 1 | -0.0415458 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0405244 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0404361 |
| IER3 | immediate early response 3 | -0.0399905 |
| NCKAP5 | NCK-associated protein 5 | -0.0396387 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0395425 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0394651 |
| RPL23 | ribosomal protein L23 | -0.0380929 |
| FMNL2 | formin-like 2 | -0.0380723 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0378563 |
| AHNAK | AHNAK nucleoprotein | -0.03764 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0367824 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0363053 |
| RPS12 | ribosomal protein S12 | -0.0361443 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0359187 |
| RPS8 | ribosomal protein S8 | -0.0352724 |
| SNX9 | sorting nexin 9 | -0.0352374 |
| RPL12 | ribosomal protein L12 | -0.0350957 |
| CDH13 | cadherin 13 | -0.0341631 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0336942 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0336656 |
| RPL19 | ribosomal protein L19 | -0.0334027 |
| ITGA1 | integrin, alpha 1 | -0.0316736 |
| RPL31 | ribosomal protein L31 | -0.0307323 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0304785 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.029858 |
| ENO1 | enolase 1, (alpha) | -0.0296015 |
| RPL37A | ribosomal protein L37a | -0.0286257 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0284015 |
| RACK1 | receptor for activated C kinase 1 | -0.0282847 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0281731 |
| PRRX1 | paired related homeobox 1 | -0.0278455 |
| DNER | delta/notch-like EGF repeat containing | -0.0273381 |
| CALR | calreticulin | -0.0273342 |
| ADM | adrenomedullin | -0.0270282 |
| INSIG1 | insulin induced gene 1 | -0.0270021 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0268679 |
| COL3A1 | collagen, type III, alpha 1 | -0.0267946 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0265973 |
| FAM13A | family with sequence similarity 13, member A | -0.0264997 |
| RPS19 | ribosomal protein S19 | -0.026281 |
| RPS24 | ribosomal protein S24 | -0.0261045 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0260558 |
| S100A9 | S100 calcium binding protein A9 | -0.025939 |
| RPS25 | ribosomal protein S25 | -0.025901 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0258279 |
| NPTX1 | neuronal pentraxin I | -0.0252482 |
| TMEM165 | transmembrane protein 165 | -0.0252121 |
| RPS23 | ribosomal protein S23 | -0.0250747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0250521 |
| MEIS1 | Meis homeobox 1 | -0.025041 |
| RPS14 | ribosomal protein S14 | -0.0248242 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0247971 |
