| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sonidegib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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101 genes differentially expressed following the Sonidegib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.173725 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.171814 |
| RPLP2 | ribosomal protein, large, P2 | 0.138913 |
| FTL | ferritin, light polypeptide | 0.119556 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.114032 |
| RPS13 | ribosomal protein S13 | 0.102454 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0993667 |
| RPS5 | ribosomal protein S5 | 0.0882188 |
| LMO7 | LIM domain 7 | 0.0830817 |
| LDHA | lactate dehydrogenase A | 0.0825984 |
| RPL36 | ribosomal protein L36 | 0.0811828 |
| RPS19 | ribosomal protein S19 | 0.0807421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0736085 |
| RPS27A | ribosomal protein S27a | 0.0731637 |
| MT2A | metallothionein 2A | 0.0715031 |
| RPS17 | ribosomal protein S17 | 0.0695316 |
| RPS8 | ribosomal protein S8 | 0.0657374 |
| S100A10 | S100 calcium binding protein A10 | 0.0633872 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0607221 |
| RPL13A | ribosomal protein L13a | 0.0590298 |
| RPS6 | ribosomal protein S6 | 0.0570427 |
| RPLP0 | ribosomal protein, large, P0 | 0.0567069 |
| RPS12 | ribosomal protein S12 | 0.052581 |
| FN1 | fibronectin 1 | 0.0520018 |
| FAT1 | FAT atypical cadherin 1 | 0.0499345 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0491219 |
| ENO1 | enolase 1, (alpha) | 0.0489852 |
| EXT1 | exostosin glycosyltransferase 1 | 0.048174 |
| RPL19 | ribosomal protein L19 | 0.0476683 |
| PGK1 | phosphoglycerate kinase 1 | 0.047127 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0463575 |
| RPL8 | ribosomal protein L8 | 0.0455228 |
| RPL37A | ribosomal protein L37a | 0.0453915 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0429644 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.041709 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0411595 |
| DST | dystonin | 0.0401127 |
| RPL23 | ribosomal protein L23 | 0.0386058 |
| RPS25 | ribosomal protein S25 | 0.0377657 |
| RPL27A | ribosomal protein L27a | 0.0360003 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0344074 |
| RPL7A | ribosomal protein L7a | 0.0340079 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0336597 |
| RPL5 | ribosomal protein L5 | 0.0331202 |
| MYO1E | myosin IE | 0.0317982 |
| ASPH | aspartate beta-hydroxylase | 0.0312156 |
| RPS21 | ribosomal protein S21 | 0.0297781 |
| RACK1 | receptor for activated C kinase 1 | 0.0264331 |
| RPL18 | ribosomal protein L18 | 0.0221916 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0170895 |
| RPS3 | ribosomal protein S3 | 0.0156814 |
| FNDC3B | fibronectin type III domain containing 3B | 0.015173 |
| TMSB10 | thymosin beta 10 | 0.0127911 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.012154 |
| CANX | calnexin | 0.00813981 |
| ACTG1 | actin gamma 1 | 0.00447979 |
| PTMA | prothymosin, alpha | 7.04343E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.26895 |
| EGFR | epidermal growth factor receptor | -0.250227 |
| PTK2 | protein tyrosine kinase 2 | -0.15177 |
| VIM | vimentin | -0.146675 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.120581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.120303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109954 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.102824 |
| SMYD3 | SET and MYND domain containing 3 | -0.100237 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0891352 |
| NDRG1 | N-myc downstream regulated 1 | -0.0830355 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0799723 |
| RAB10 | RAB10, member RAS oncogene family | -0.0767134 |
| EFNA5 | ephrin-A5 | -0.0748007 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0693972 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0670909 |
| PRKCA | protein kinase C, alpha | -0.0653541 |
| SBF2 | SET binding factor 2 | -0.0651006 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0620183 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0584841 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0583573 |
| TENM3 | teneurin transmembrane protein 3 | -0.0559831 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0530163 |
| USP34 | ubiquitin specific peptidase 34 | -0.0510398 |
| TPM4 | tropomyosin 4 | -0.049178 |
| MYO6 | myosin VI | -0.0474249 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0463252 |
| HLA-A | major histocompatibility complex, class I, A | -0.042456 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0422214 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0408772 |
| PKM | pyruvate kinase, muscle | -0.0395619 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0381761 |
| CALR | calreticulin | -0.031601 |
| ANXA2 | annexin A2 | -0.028856 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0253028 |
| CD44 | CD44 molecule (Indian blood group) | -0.0186672 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0159981 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0154394 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0150405 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0116563 |
| RPLP1 | ribosomal protein, large, P1 | -0.00694296 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00673327 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00360512 |
| COPA | coatomer protein complex, subunit alpha | -0.00360231 |
