Sorafenib Gene Set
Genes
31 kinases inhibited by the Sorafenib small molecule from the KinomeScan Kinase Inhibitor Targets dataset.
| Symbol |
Name |
Standardized Value |
|
CSF1R
|
colony stimulating factor 1 receptor
|
1.36211
|
|
RAF1
|
Raf-1 proto-oncogene, serine/threonine kinase
|
1.36211
|
|
MUSK
|
muscle, skeletal, receptor tyrosine kinase
|
1.36211
|
|
RET
|
ret proto-oncogene
|
1.36211
|
|
MKNK2
|
MAP kinase interacting serine/threonine kinase 2
|
1.36211
|
|
CDKL2
|
cyclin-dependent kinase-like 2 (CDC2-related kinase)
|
1.34449
|
|
FLT3
|
fms-related tyrosine kinase 3
|
1.32726
|
|
CDKL3
|
cyclin-dependent kinase-like 3
|
1.31878
|
|
HIPK3
|
homeodomain interacting protein kinase 3
|
1.31878
|
|
NTRK3
|
neurotrophic tyrosine kinase, receptor, type 3
|
1.3104
|
|
AURKB
|
aurora kinase B
|
1.3104
|
|
TAOK3
|
TAO kinase 3
|
1.30212
|
|
MAPK15
|
mitogen-activated protein kinase 15
|
1.29393
|
|
CDK8
|
cyclin-dependent kinase 8
|
1.25436
|
|
TAOK2
|
TAO kinase 2
|
1.23916
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
1.20271
|
|
EPHB6
|
EPH receptor B6
|
1.1424
|
|
EPHA8
|
EPH receptor A8
|
1.08845
|
|
TIE1
|
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
|
1.08283
|
|
CDK7
|
cyclin-dependent kinase 7
|
1.0718
|
|
ZAK
|
sterile alpha motif and leucine zipper containing kinase AZK
|
1.0718
|
|
HIPK2
|
homeodomain interacting protein kinase 2
|
1.06105
|
|
FGFR1
|
fibroblast growth factor receptor 1
|
1.02071
|
|
LCK
|
LCK proto-oncogene, Src family tyrosine kinase
|
1.02071
|
|
EPHA3
|
EPH receptor A3
|
1.00208
|
|
MERTK
|
MER proto-oncogene, tyrosine kinase
|
0.993117
|
|
FRK
|
fyn-related Src family tyrosine kinase
|
0.959553
|
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5
|
0.936602
|
|
AXL
|
AXL receptor tyrosine kinase
|
0.915387
|
|
CDK14
|
cyclin-dependent kinase 14
|
0.889549
|
|
EPHA6
|
EPH receptor A6
|
0.871827
|
