Sorafenib Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

31 kinases inhibited by the Sorafenib small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
CSF1R colony stimulating factor 1 receptor 1.36211
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.36211
MUSK muscle, skeletal, receptor tyrosine kinase 1.36211
RET ret proto-oncogene 1.36211
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.36211
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.34449
FLT3 fms-related tyrosine kinase 3 1.32726
CDKL3 cyclin-dependent kinase-like 3 1.31878
HIPK3 homeodomain interacting protein kinase 3 1.31878
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.3104
AURKB aurora kinase B 1.3104
TAOK3 TAO kinase 3 1.30212
MAPK15 mitogen-activated protein kinase 15 1.29393
CDK8 cyclin-dependent kinase 8 1.25436
TAOK2 TAO kinase 2 1.23916
MKNK1 MAP kinase interacting serine/threonine kinase 1 1.20271
EPHB6 EPH receptor B6 1.1424
EPHA8 EPH receptor A8 1.08845
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.08283
CDK7 cyclin-dependent kinase 7 1.0718
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.0718
HIPK2 homeodomain interacting protein kinase 2 1.06105
FGFR1 fibroblast growth factor receptor 1 1.02071
LCK LCK proto-oncogene, Src family tyrosine kinase 1.02071
EPHA3 EPH receptor A3 1.00208
MERTK MER proto-oncogene, tyrosine kinase 0.993117
FRK fyn-related Src family tyrosine kinase 0.959553
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.936602
AXL AXL receptor tyrosine kinase 0.915387
CDK14 cyclin-dependent kinase 14 0.889549
EPHA6 EPH receptor A6 0.871827