Sotalol Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. (Chemical Entities of Biological Interest Ontology, CHEBI_63622)
External Link http://www.hmdb.ca/metabolites/HMDB14632
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Genes

3 interacting proteins for the Sotalol metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2