Sphingolipid metabolism in senescence Gene Set
Genes
28 proteins participating in the Sphingolipid metabolism in senescence pathway from the WikiPathways Pathways 2024 dataset.
| Symbol |
Name |
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
|
CDK2
|
cyclin-dependent kinase 2
|
|
CDK4
|
cyclin-dependent kinase 4
|
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
|
CERS2
|
ceramide synthase 2
|
|
CERS4
|
ceramide synthase 4
|
|
DEGS1
|
delta(4)-desaturase, sphingolipid 1
|
|
E2F1
|
E2F transcription factor 1
|
|
GBA1
|
glucosylceramidase beta 1
|
|
GLB1
|
galactosidase, beta 1
|
|
KDSR
|
3-ketodihydrosphingosine reductase
|
|
MAPK1
|
mitogen-activated protein kinase 1
|
|
MTOR
|
mechanistic target of rapamycin (serine/threonine kinase)
|
|
PLCB1
|
phospholipase C, beta 1 (phosphoinositide-specific)
|
|
PRKCA
|
protein kinase C, alpha
|
|
PRKCB
|
protein kinase C, beta
|
|
RB1
|
retinoblastoma 1
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
|
S1PR1
|
sphingosine-1-phosphate receptor 1
|
|
S1PR2
|
sphingosine-1-phosphate receptor 2
|
|
S1PR5
|
sphingosine-1-phosphate receptor 5
|
|
SGMS2
|
sphingomyelin synthase 2
|
|
SGPP1
|
sphingosine-1-phosphate phosphatase 1
|
|
SMPD3
|
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
|
|
SPHK1
|
sphingosine kinase 1
|
|
SPTLC1
|
serine palmitoyltransferase, long chain base subunit 1
|
|
TERT
|
telomerase reverse transcriptase
|
|
UGCG
|
UDP-glucose ceramide glucosyltransferase
|
