Spinal Fractures Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Broken bones in the vertebral column. (Experimental Factor Ontology, EFO_0003902)
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33 genes associated with the Spinal Fractures phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ALOX12 arachidonate 12-lipoxygenase
APOE apolipoprotein E
AR androgen receptor
CALCR calcitonin receptor
CASR calcium-sensing receptor
COL1A1 collagen, type I, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
ESR1 estrogen receptor 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GHR growth hormone receptor
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IL1A interleukin 1, alpha
IL6 interleukin 6
LCT lactase
LEPR leptin receptor
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MATN3 matrilin 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PLXNA2 plexin A2
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
SOST sclerostin
TGFB1 transforming growth factor, beta 1
THSD7A thrombospondin, type I, domain containing 7A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT10B wingless-type MMTV integration site family, member 10B