Spondylarthritis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0949690
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Genes

152 genes associated with the disease Spondylarthritis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACAD8 acyl-CoA dehydrogenase family, member 8
ACR acrosin
ACVR1 activin A receptor, type I
ADA adenosine deaminase
AHSG alpha-2-HS-glycoprotein
ALDOA aldolase A, fructose-bisphosphate
ANTXR2 anthrax toxin receptor 2
B2M beta-2-microglobulin
BANK1 B-cell scaffold protein with ankyrin repeats 1
BDNF brain-derived neurotrophic factor
C6ORF25 chromosome 6 open reading frame 25
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD14 CD14 molecule
CD163 CD163 molecule
CD68 CD68 molecule
CD69 CD69 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDA cytidine deaminase
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CPQ carboxypeptidase Q
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENO1 enolase 1, (alpha)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GPR65 G protein-coupled receptor 65
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL17A interleukin 17A
IL17B interleukin 17B
IL17F interleukin 17F
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IL20 interleukin 20
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL24 interleukin 24
IL25 interleukin 25
IL26 interleukin 26
IL33 interleukin 33
IL37 interleukin 37
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IRF1 interferon regulatory factor 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KREMEN1 kringle containing transmembrane protein 1
LPA lipoprotein, Lp(a)
LRP5 low density lipoprotein receptor-related protein 5
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK14 mitogen-activated protein kinase 14
MBL2 mannose-binding lectin (protein C) 2, soluble
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCAM melanoma cell adhesion molecule
MEFV Mediterranean fever
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICA MHC class I polypeptide-related sequence A
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MRAP melanocortin 2 receptor accessory protein
MSC musculin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYDGF myeloid-derived growth factor
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NLRP2 NLR family, pyrin domain containing 2
NOD2 nucleotide-binding oligomerization domain containing 2
NPPA natriuretic peptide A
PADI2 peptidyl arginine deiminase, type II
PADI4 peptidyl arginine deiminase, type IV
PDLIM7 PDZ and LIM domain 7 (enigma)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PRL prolactin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTX3 pentraxin 3, long
RBM45 RNA binding motif protein 45
RIOX1 ribosomal oxygenase 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SETD2 SET domain containing 2
SFTPA2 surfactant protein A2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLPI secretory leukocyte peptidase inhibitor
SMAD1 SMAD family member 1
SOAT1 sterol O-acyltransferase 1
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TBX21 T-box 21
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TPMT thiopurine S-methyltransferase
TPO thyroid peroxidase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WDHD1 WD repeat and HMG-box DNA binding protein 1
WISP1 WNT1 inducible signaling pathway protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3HAV1 zinc finger CCCH-type, antiviral 1