Spondylitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

155 genes co-occuring with the disease Spondylitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CRP C-reactive protein, pentraxin-related 3.001
IL17A interleukin 17A 2.628
TNF tumor necrosis factor 2.549
ERAP1 endoplasmic reticulum aminopeptidase 1 2.526
SAA2 serum amyloid A2 2.472
SAA1 serum amyloid A1 2.44
IL23R interleukin 23 receptor 2.403
HLA-B major histocompatibility complex, class I, B 2.392
IL22 interleukin 22 2.124
IL6 interleukin 6 2.043
HLA-C major histocompatibility complex, class I, C 2.043
ACAN aggrecan 2.008
IFNG interferon, gamma 2.005
SOST sclerostin 2.004
IL17F interleukin 17F 2.002
CD4 CD4 molecule 1.992
IL23A interleukin 23, alpha subunit p19 1.979
IL1B interleukin 1, beta 1.976
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.904
MRAP melanocortin 2 receptor accessory protein 1.895
ERAP2 endoplasmic reticulum aminopeptidase 2 1.894
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.888
IL1A interleukin 1, alpha 1.839
CD8A CD8a molecule 1.837
IL17RA interleukin 17 receptor A 1.792
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.788
IL10 interleukin 10 1.704
ALB albumin 1.648
IL25 interleukin 25 1.611
SYNJ2BP synaptojanin 2 binding protein 1.59
ANTXR2 anthrax toxin receptor 2 1.588
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.575
TYK2 tyrosine kinase 2 1.575
DYNLT1 dynein, light chain, Tctex-type 1 1.573
B2M beta-2-microglobulin 1.57
CARD9 caspase recruitment domain family, member 9 1.565
PDE4A phosphodiesterase 4A, cAMP-specific 1.553
ANKH ANKH inorganic pyrophosphate transport regulator 1.544
IL4 interleukin 4 1.532
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.528
IL1R2 interleukin 1 receptor, type II 1.524
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.514
IL2 interleukin 2 1.501
JAK1 Janus kinase 1 1.5
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.495
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.488
CXCL8 chemokine (C-X-C motif) ligand 8 1.485
MMP3 matrix metallopeptidase 3 1.484
IL17D interleukin 17D 1.476
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.471
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.467
TLR4 toll-like receptor 4 1.461
NOD2 nucleotide-binding oligomerization domain containing 2 1.451
RORC RAR-related orphan receptor C 1.451
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.444
IL17C interleukin 17C 1.44
TGFB1 transforming growth factor, beta 1 1.437
IL17RC interleukin 17 receptor C 1.434
CD80 CD80 molecule 1.423
CCL20 chemokine (C-C motif) ligand 20 1.415
BGLAP bone gamma-carboxyglutamate (gla) protein 1.412
CREG1 cellular repressor of E1A-stimulated genes 1 1.411
IL12RB1 interleukin 12 receptor, beta 1 1.411
JAK2 Janus kinase 2 1.378
IL6R interleukin 6 receptor 1.376
KIF21B kinesin family member 21B 1.356
JAK3 Janus kinase 3 1.343
HLA-A major histocompatibility complex, class I, A 1.339
IL17B interleukin 17B 1.339
CLEC7A C-type lectin domain family 7, member A 1.339
TRAF3IP2 TRAF3 interacting protein 2 1.337
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.329
IL1F10 interleukin 1 family, member 10 (theta) 1.305
CCL2 chemokine (C-C motif) ligand 2 1.303
PRTN3 proteinase 3 1.278
CAMP cathelicidin antimicrobial peptide 1.271
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.269
IL1RN interleukin 1 receptor antagonist 1.264
LCE3B late cornified envelope 3B 1.264
TNIP1 TNFAIP3 interacting protein 1 1.264
IL18 interleukin 18 1.259
PTH parathyroid hormone 1.256
LCE3A late cornified envelope 3A 1.253
IL13 interleukin 13 1.247
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.246
BMP2 bone morphogenetic protein 2 1.246
TLR2 toll-like receptor 2 1.242
CXCL10 chemokine (C-X-C motif) ligand 10 1.238
IL26 interleukin 26 1.236
FOXP3 forkhead box P3 1.234
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.227
LCE3C late cornified envelope 3C 1.215
CD68 CD68 molecule 1.214
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.206
SP7 Sp7 transcription factor 1.2
TBX21 T-box 21 1.195
MEFV Mediterranean fever 1.189
IL36RN interleukin 36 receptor antagonist 1.181
IL7 interleukin 7 1.18
CD28 CD28 molecule 1.178
RUNX2 runt-related transcription factor 2 1.176
IL36R interleukin 36 receptor 1.157
CD163 CD163 molecule 1.153
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.145
WBP2NL WBP2 N-terminal like 1.132
STAT1 signal transducer and activator of transcription 1, 91kDa 1.121
ADA adenosine deaminase 1.117
CCR6 chemokine (C-C motif) receptor 6 1.11
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 1.108
PTGIS prostaglandin I2 (prostacyclin) synthase 1.104
NELFCD negative elongation factor complex member C/D 1.103
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.099
INS insulin 1.095
IL9 interleukin 9 1.094
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 1.092
IL15 interleukin 15 1.09
CARD14 caspase recruitment domain family, member 14 1.09
HP haptoglobin 1.09
IL17RE interleukin 17 receptor E 1.089
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.084
CCRL2 chemokine (C-C motif) receptor-like 2 1.084
MYD88 myeloid differentiation primary response 88 1.082
INHA inhibin, alpha 1.072
JUN jun proto-oncogene 1.068
C12ORF57 chromosome 12 open reading frame 57 1.066
TRADD TNFRSF1A-associated via death domain 1.065
CSF3 colony stimulating factor 3 (granulocyte) 1.062
ANO6 anoctamin 6 1.062
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 1.06
RUNX3 runt-related transcription factor 3 1.058
CKB creatine kinase, brain 1.054
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.052
LNPEP leucyl/cystinyl aminopeptidase 1.051
MMP13 matrix metallopeptidase 13 1.048
CTSK cathepsin K 1.045
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.041
CKMT1B creatine kinase, mitochondrial 1B 1.04
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.037
CKM creatine kinase, muscle 1.036
HAPLN1 hyaluronan and proteoglycan link protein 1 1.031
COL2A1 collagen, type II, alpha 1 1.03
C6ORF47 chromosome 6 open reading frame 47 1.03
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.028
MPO myeloperoxidase 1.024
DAZL deleted in azoospermia-like 1.023
NPEPPS aminopeptidase puromycin sensitive 1.02
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.02
IL1R1 interleukin 1 receptor, type I 1.017
FBXL19 F-box and leucine-rich repeat protein 19 1.013
WIPF3 WAS/WASL interacting protein family, member 3 1.013
CD1D CD1d molecule 1.009
IL33 interleukin 33 1.008
F2 coagulation factor II (thrombin) 1.002
CD1C CD1c molecule 1.002
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.001