Spondylolysis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A bone structure disease that involves a defect located_in lumbar vertebral column. (Human Disease Ontology, DOID_2300)
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Genes

45 genes co-occuring with the disease Spondylolysis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.356
ACAN aggrecan 1.751
BMP2 bone morphogenetic protein 2 1.665
CTSK cathepsin K 1.588
LTV1 LTV1 ribosome biogenesis factor 1.569
TBX6 T-box 6 1.524
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.474
CLCN7 chloride channel, voltage-sensitive 7 1.39
GDF5 growth differentiation factor 5 1.383
SLC7A4 solute carrier family 7, member 4 1.335
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 1.325
CRP C-reactive protein, pentraxin-related 1.319
BMP7 bone morphogenetic protein 7 1.315
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 1.292
PTH parathyroid hormone 1.288
SOX9 SRY (sex determining region Y)-box 9 1.287
COL1A1 collagen, type I, alpha 1 1.236
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 1.223
ST18 suppression of tumorigenicity 18, zinc finger 1.222
AJAP1 adherens junctions associated protein 1 1.218
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.159
PRELP proline/arginine-rich end leucine-rich repeat protein 1.145
MYO10 myosin X 1.144
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.143
STAMBP STAM binding protein 1.136
AMIGO2 adhesion molecule with Ig-like domain 2 1.135
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 1.131
TAC1 tachykinin, precursor 1 1.123
RTL1 retrotransposon-like 1 1.102
MESD mesoderm development LRP chaperone 1.092
TENT5A terminal nucleotidyltransferase 5A 1.091
CRTAC1 cartilage acidic protein 1 1.088
OAF OAF homolog (Drosophila) 1.085
CXCL6 chemokine (C-X-C motif) ligand 6 1.081
NOTO notochord homeobox 1.067
COL9A1 collagen, type IX, alpha 1 1.062
PAGE2 P antigen family, member 2 (prostate associated) 1.058
IRX5 iroquois homeobox 5 1.049
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.048
FAM169A family with sequence similarity 169, member A 1.044
ANKH ANKH inorganic pyrophosphate transport regulator 1.038
ASIC2 acid sensing (proton gated) ion channel 2 1.007
COL2A1 collagen, type II, alpha 1 1.005
IHH indian hedgehog 1.004
MMP3 matrix metallopeptidase 3 1.002