Squamous Cell Carcinoma Of Skin Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0553723
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Genes

410 genes associated with the disease Squamous Cell Carcinoma Of Skin in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
AGER advanced glycosylation end product-specific receptor
AGRP agouti related neuropeptide
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AIM2 absent in melanoma 2
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKRD36B ankyrin repeat domain 36B
APAF1 apoptotic peptidase activating factor 1
APRT adenine phosphoribosyltransferase
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
ARHGAP24 Rho GTPase activating protein 24
ARTN artemin
ATF3 activating transcription factor 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L12 BCL2-like 12 (proline rich)
BECN1 beclin 1, autophagy related
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD4 bromodomain containing 4
BRS3 bombesin-like receptor 3
C3 complement component 3
CABIN1 calcineurin binding protein 1
CADM1 cell adhesion molecule 1
CAMP cathelicidin antimicrobial peptide
CARD11 caspase recruitment domain family, member 11
CARD14 caspase recruitment domain family, member 14
CAVIN1 caveolae associated protein 1
CCL8 chemokine (C-C motif) ligand 8
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD274 CD274 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD68 CD68 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDK16 cyclin-dependent kinase 16
CDK6 cyclin-dependent kinase 6
CDK9 cyclin-dependent kinase 9
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFB complement factor B
CFDP1 craniofacial development protein 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKAP4 cytoskeleton-associated protein 4
CKS1B CDC28 protein kinase regulatory subunit 1B
CLDN1 claudin 1
CLDN11 claudin 11
CLDN7 claudin 7
CLEC2D C-type lectin domain family 2, member D
COL17A1 collagen, type XVII, alpha 1
COL7A1 collagen, type VII, alpha 1
COX2
CREBBP CREB binding protein
CRIP2 cysteine-rich protein 2
CRISP2 cysteine-rich secretory protein 2
CRMP1 collapsin response mediator protein 1
CRNKL1 crooked neck pre-mRNA splicing factor 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR6 chemokine (C-X-C motif) receptor 6
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DCTN6 dynactin 6
DDB2 damage-specific DNA binding protein 2, 48kDa
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DENR density-regulated protein
DLC1 DLC1 Rho GTPase activating protein
DLX3 distal-less homeobox 3
DNM1L dynamin 1-like
DPH3 diphthamide biosynthesis 3
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFS embryonal Fyn-associated substrate
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR3 early growth response 3
EIF4E eukaryotic translation initiation factor 4E
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EPHA1 EPH receptor A1
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBIN erbb2 interacting protein
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FAM114A2 family with sequence similarity 114, member A2
FAM134B family with sequence similarity 134, member B
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOPNL FGFR1OP N-terminal like
FOXC2 forkhead box C2
FOXE1 forkhead box E1
FOXG1 forkhead box G1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FYN FYN proto-oncogene, Src family tyrosine kinase
G0S2 G0/G1 switch 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45A growth arrest and DNA-damage-inducible, alpha
GEMIN4 gem (nuclear organelle) associated protein 4
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLB1 galactosidase, beta 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPER1 G protein-coupled estrogen receptor 1
GPR1 G protein-coupled receptor 1
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
GRHL3 grainyhead-like 3 (Drosophila)
GRN granulin
HBEGF heparin-binding EGF-like growth factor
HDAC3 histone deacetylase 3
HDAC9 histone deacetylase 9
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HOXA9 homeobox A9
HOXB7 homeobox B7
HPGDS hematopoietic prostaglandin D synthase
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
IFI27 interferon, alpha-inducible protein 27
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL22 interleukin 22
IL6 interleukin 6
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IRF3 interferon regulatory factor 3
IRF4 interferon regulatory factor 4
ISG15 ISG15 ubiquitin-like modifier
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
IVL involucrin
JAK1 Janus kinase 1
KLF4 Kruppel-like factor 4 (gut)
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT7 keratin 7, type II
KRT72 keratin 72, type II
KRT8 keratin 8, type II
KTN1 kinectin 1 (kinesin receptor)
KYNU kynureninase
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LIMK1 LIM domain kinase 1
LMLN leishmanolysin-like (metallopeptidase M8 family)
LMNA lamin A/C
LPAR2 lysophosphatidic acid receptor 2
LPP LIM domain containing preferred translocation partner in lipoma
LZTS1 leucine zipper, putative tumor suppressor 1
MAGEA12 melanoma antigen family A12
MAL mal, T-cell differentiation protein
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
METTL3 methyltransferase like 3
MFAP1 microfibrillar-associated protein 1
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MMUT methylmalonyl-CoA mutase
MRGBP MRG/MORF4L binding protein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBPF1 neuroblastoma breakpoint family, member 1
NCAM1 neural cell adhesion molecule 1
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NET1 neuroepithelial cell transforming 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSD2 nuclear receptor binding SET domain protein 2
OCA2 oculocutaneous albinism II
OCLN occludin
ODC1 ornithine decarboxylase 1
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OSM oncostatin M
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARD3 par-3 family cell polarity regulator
PARK2 parkin RBR E3 ubiquitin protein ligase
PCBP1 poly(rC) binding protein 1
PCBP4 poly(rC) binding protein 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPN podoplanin
PEBP1 phosphatidylethanolamine binding protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
POLH polymerase (DNA directed), eta
POLQ polymerase (DNA directed), theta
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRAF2 PRA1 domain family, member 2
PRPF38B pre-mRNA processing factor 38B
PRSS55 protease, serine, 55
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTPRD protein tyrosine phosphatase, receptor type, D
RAB23 RAB23, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALY RALY heterogeneous nuclear ribonucleoprotein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBM45 RNA binding motif protein 45
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RET ret proto-oncogene
RHOBTB1 Rho-related BTB domain containing 1
RIPK4 receptor-interacting serine-threonine kinase 4
RMDN1 regulator of microtubule dynamics 1
RMDN2 regulator of microtubule dynamics 2
RMDN3 regulator of microtubule dynamics 3
RNF2 ring finger protein 2
RPE65 retinal pigment epithelium-specific protein 65kDa
RSPO1 R-spondin 1
RUNX1 runt-related transcription factor 1
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCLY selenocysteine lyase
SDC1 syndecan 1
SDC2 syndecan 2
SEC16A SEC16 homolog A (S. cerevisiae)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFRP1 secreted frizzled-related protein 1
SFRP5 secreted frizzled-related protein 5
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SIN3A SIN3 transcription regulator family member A
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC45A2 solute carrier family 45, member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMPX small muscle protein, X-linked
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOAT1 sterol O-acyltransferase 1
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SPHK2 sphingosine kinase 2
SPRR1A small proline-rich protein 1A
SPZ1 spermatogenic leucine zipper 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCIN1 SRC kinase signaling inhibitor 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SSTR4 somatostatin receptor 4
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK19 serine/threonine kinase 19
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYBU syntabulin (syntaxin-interacting)
SYT1 synaptotagmin I
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAL1 T-cell acute lymphocytic leukemia 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFEB transcription factor EB
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TICAM2 toll-like receptor adaptor molecule 2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TINCR tissue differentiation-inducing non-protein coding RNA
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TIPE2 TNF alpha induced protein 8 like 2
TLR4 toll-like receptor 4
TMC6 transmembrane channel-like 6
TMC8 transmembrane channel-like 8
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMPRSS13 transmembrane protease, serine 13
TNC tenascin C
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TP53 tumor protein p53
TP53RK TP53 regulating kinase
TP63 tumor protein p63
TP73 tumor protein p73
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM16 tripartite motif containing 16
TRIM32 tripartite motif containing 32
TRPS1 trichorhinophalangeal syndrome I
TSPAN1 tetraspanin 1
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYR tyrosinase
UBA5 ubiquitin-like modifier activating enzyme 5
USF1 upstream transcription factor 1
USP8 ubiquitin specific peptidase 8
UTRN utrophin
UVRAG UV radiation resistance associated
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
VSNL1 visinin-like 1
WNK1 WNK lysine deficient protein kinase 1
WNT1 wingless-type MMTV integration site family, member 1
WWOX WW domain containing oxidoreductase
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
ZEB1 zinc finger E-box binding homeobox 1
ZHX2 zinc fingers and homeoboxes 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF654 zinc finger protein 654