Squamous Cell Carcinoma Of Tongue Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0349566
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Genes

381 genes associated with the disease Squamous Cell Carcinoma Of Tongue in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM10 ADAM metallopeptidase domain 10
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPTL4 angiopoietin-like 4
ANPEP alanyl (membrane) aminopeptidase
ANTXR2 anthrax toxin receptor 2
AP5B1 adaptor-related protein complex 5, beta 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP5 aquaporin 5
ARF6 ADP-ribosylation factor 6
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL4C ADP-ribosylation factor-like 4C
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASCC1 activating signal cointegrator 1 complex subunit 1
ATF3 activating transcription factor 3
ATG4B autophagy related 4B, cysteine peptidase
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L12 BCL2-like 12 (proline rich)
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP1 bone morphogenetic protein 1
BRCA1 breast cancer 1, early onset
BRD4 bromodomain containing 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BSG basigin (Ok blood group)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBR1 carbonyl reductase 1
CBX3 chromobox homolog 3
CCK cholecystokinin
CCL20 chemokine (C-C motif) ligand 20
CCL22 chemokine (C-C motif) ligand 22
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD274 CD274 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD6 CD6 molecule
CD63 CD63 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDT1 chromatin licensing and DNA replication factor 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP135 centrosomal protein 135kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CKAP4 cytoskeleton-associated protein 4
CLDN1 claudin 1
CLDN7 claudin 7
CLOCK clock circadian regulator
CNOT7 CCR4-NOT transcription complex, subunit 7
CNOT8 CCR4-NOT transcription complex, subunit 8
CNTN1 contactin 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COX2
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CSDE1 cold shock domain containing E1, RNA-binding
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
CTRL chymotrypsin-like
CTSC cathepsin C
CTSK cathepsin K
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK1 death-associated protein kinase 1
DCTN6 dynactin 6
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DICER1 dicer 1, ribonuclease type III
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7
DND1 DND microRNA-mediated repression inhibitor 1
DNER delta/notch-like EGF repeat containing
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELP1 elongator acetyltransferase complex subunit 1
EPAS1 endothelial PAS domain protein 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHA8 EPH receptor A8
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERVH48-1 endogenous retrovirus group 48, member 1
ETV4 ets variant 4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FADD Fas (TNFRSF6)-associated via death domain
FBLIM1 filamin binding LIM protein 1
FBXO32 F-box protein 32
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FMNL3 formin-like 3
FNDC3B fibronectin type III domain containing 3B
FOSL2 FOS-like antigen 2
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FRMD4A FERM domain containing 4A
FSCN1 fascin actin-bundling protein 1
FZD2 frizzled class receptor 2
FZD7 frizzled class receptor 7
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GBP6 guanylate binding protein family, member 6
GEMIN2 gem (nuclear organelle) associated protein 2
GJA1 gap junction protein, alpha 1, 43kDa
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GOPC golgi-associated PDZ and coiled-coil motif containing
GORASP1 golgi reassembly stacking protein 1, 65kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2H5 general transcription factor IIH, polypeptide 5
GUK1 guanylate kinase 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HK2 hexokinase 2
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HOXD8 homeobox D8
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPG2 heparan sulfate proteoglycan 2
IFI27 interferon, alpha-inducible protein 27
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL10 interleukin 10
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL33 interleukin 33
ING5 inhibitor of growth family, member 5
INSR insulin receptor
IRX1 iroquois homeobox 1
IRX5 iroquois homeobox 5
ISYNA1 inositol-3-phosphate synthase 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA7 integrin, alpha 7
ITGB5 integrin, beta 5
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAK3 Janus kinase 3
KAT2B K(lysine) acetyltransferase 2B
KAT6B K(lysine) acetyltransferase 6B
KDM1A lysine (K)-specific demethylase 1A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LAMC2 laminin, gamma 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LINC00961 long intergenic non-protein coding RNA 961
LOXL2 lysyl oxidase-like 2
LPA lipoprotein, Lp(a)
LRP6 low density lipoprotein receptor-related protein 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MACC1 metastasis associated in colon cancer 1
MAK16 MAK16 homolog (S. cerevisiae)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MARCHF1 membrane associated ring-CH-type finger 1
MAU2 MAU2 sister chromatid cohesion factor
MCM2 minichromosome maintenance complex component 2
MFAP5 microfibrillar associated protein 5
MFF mitochondrial fission factor
MGMT O-6-methylguanine-DNA methyltransferase
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTUS1 microtubule associated tumor suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBPAP MYCBP associated protein
MYO6 myosin VI
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 NME1-NME2 readthrough
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOP53 NOP53 ribosome biogenesis factor
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOX4 NADPH oxidase 4
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRP1 neuropilin 1
NRP2 neuropilin 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OLFM4 olfactomedin 4
OSR1 odd-skipped related transciption factor 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARVB parvin, beta
PAX6 paired box 6
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGPEP1 pyroglutamyl-peptidase I
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKM pyruvate kinase, muscle
PLAU plasminogen activator, urokinase
PLS3 plastin 3
PNO1 partner of NOB1 homolog (S. cerevisiae)
PODXL podocalyxin-like
POU5F1 POU class 5 homeobox 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDX1 peroxiredoxin 1
PRL prolactin
PROM1 prominin 1
PRR11 proline rich 11
PRRX1 paired related homeobox 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXN paxillin
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RBMS3 RNA binding motif, single stranded interacting protein 3
RBP1 retinol binding protein 1, cellular
RDX radixin
RECQL RecQ helicase-like
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RIPK4 receptor-interacting serine-threonine kinase 4
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS6 ribosomal protein S6
RSPO2 R-spondin 2
RUNX3 runt-related transcription factor 3
SATB1 SATB homeobox 1
SCAF11 SR-related CTD-associated factor 11
SDC1 syndecan 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SFRP1 secreted frizzled-related protein 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIX2 SIX homeobox 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI2 snail family zinc finger 2
SNIP1 Smad nuclear interacting protein 1
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SOX7 SRY (sex determining region Y)-box 7
SOX8 SRY (sex determining region Y)-box 8
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SPRR2A small proline-rich protein 2A
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM2 serine/arginine repetitive matrix 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIP1 stress-induced phosphoprotein 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYT1 synaptotagmin I
TAS2R13 taste receptor, type 2, member 13
TCF3 transcription factor 3
TERT telomerase reverse transcriptase
TFE3 transcription factor binding to IGHM enhancer 3
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TICAM2 toll-like receptor adaptor molecule 2
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM40 transmembrane protein 40
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRIB3 tribbles pseudokinase 3
TRIM14 tripartite motif containing 14
TUG1 taurine up-regulated 1 (non-protein coding)
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
TYMS thymidylate synthetase
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
WNK1 WNK lysine deficient protein kinase 1
WNT5A wingless-type MMTV integration site family, member 5A
WNT7A wingless-type MMTV integration site family, member 7A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPR1 xenotropic and polytropic retrovirus receptor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFX zinc finger protein, X-linked
ZNF471 zinc finger protein 471